Search
Now showing items 271-280 of 284
Gamma radiation measurements and dose rates in commonly used building materials in Cyprus
(2010)
A first comprehensive study is presented on radioactivity concentrations and dose rates in 87 commonly used materials, manufactured or imported in Cyprus, for building purposes. The natural radioactivity of 40K, 232Th, ...
Dexter Energy transfer pathways
(2016)
Energy transfer with an associated spin change of the donor and acceptor, Dexter energy transfer, is critically important in solar energy harvesting assemblies, damage protection schemes of photobiology, and organometallic ...
Molecular Dynamics in Drug Design: New Generations of Compstatin Analogs
(2012)
We report the computational and rational design of new generations of potential peptide-based inhibitors of the complement protein C3 from the compstatin family. The binding efficacy of the peptides is tested by extensive ...
Design of a modified mouse protein with ligand binding properties of its human analog by molecular dynamics simulations: The case of C3 inhibition by compstatin
(2011)
The peptide compstatin and its derivatives inhibit the complement-component protein C3 in primate mammals and are potential therapeutic agents against the unregulated activation of complement in humans, but are inactive ...
Species specificity of the complement inhibitor compstatin investigated by all-atom molecular dynamics simulations
(2010)
The development of compounds to regulate the activation of the complement system in non-primate species is of profound interest because it can provide models for human diseases. The peptide compstatin inhibits protein C3 ...
Human papillomavirus association with head and neck cancers: Understanding virus biology and using it in the development of cancer diagnostics
(2008)
The link between human papillomaviruses (HPVs) and human cervical cancers has long been established. However, HPVs are now being detected in another type of cancer not previously associated with this virus, head and neck ...
Telomeres Acquire Embryonic Stem Cell Characteristics in Induced Pluripotent Stem Cells
(2009)
Telomere shortening is associated with organismal aging. iPS cells have been recently derived from old patients
The global spread of HIV-1 subtype B epidemic
(2016)
Human immunodeficiency virus type 1 (HIV-1) was discovered in the early 1980s when the virus had already established a pandemic. For at least three decades the epidemic in the Western World has been dominated by subtype B ...
Architectural insight into inovirus-associated vectors (IAVs) and development of IAV-based vaccines inducing humoral and cellular responses: Implications in HIV-1 vaccines
(2014)
Inovirus-associated vectors (IAVs) are engineered, non-lytic, filamentous bacteriophages that are assembled primarily from thousands of copies of the major coat protein gp8 and just five copies of each of the four minor ...
Autosomal-dominant medullary cystic kidney disease type 1: Clinical and molecular findings in six large Cypriot familiesAAA
(2002)
Background. Autosomal-dominant medullary cystic kidney disease (ADMCKD), a hereditary chronic interstitial nephropathy, recently attracted attention because of the cloning or mapping of certain gene loci, namely NPHP1, ...