Browsing Ιατρική Σχολή / Medical School by Submit Date

Article

Kidney transplantation by use of splenectomy and transfusions, cadaver haplotype matching, suppressor cell assays, and T-cell monitoring

Severyn, W.; Kyriakides, George K.; Fuller, L.; Esquenazi, V.; Flaa, C.; Olson, L.; Goldsmith, C.; Miller, Jody C. (1981)

We attempted to modulate several determinants of the host immunologic profile to improve kidney transplant survival: (1) genotype matching of the cadaver donor with the recipient, (2) assessment in recipients of living ...

Article

[Testicular microlithiasis and Leydig cell proliferation in Wistar rats underwent Fowler-Stephens procedure].

Gougoudi, Evagelia; Zachariou, Zacharias; Kogia, E.; Zavitsanakis, A. (2012)

The present study investigates the outcome of Fowler-Stephens operation in prepubertal Wistar rats focused on microlithiasis and Leydig cell hyperplasia development. Thirty-eight (38) animals underwent laparoscopic ...

Article

Phase I study of etoposide, cisplatin and irinotecan triplet in patients with advanced-stage small-cell lung cancer

Briassoulis, E. Ch; Samantas, E.; Kalofonos, H. P.; Skarlos, Dimosthenis V.; Makatsoris, T.; Christodoulou, C.; Fountzilas, George; Bamias, A. T.; Dimopoulos, M. A.; Kosmidis, Paraskevas A.; Pavlidis, Nicholas (2005)

The irinotecan-cisplatin combination has emerged as a new standard for the treatment of advanced-stage small-cell lung cancer (AS-SCLC). To move forward we developed a 3-day regimen of cisplatin, etoposide and irinotecan. ...

Article

Human immunodeficiency virus in injecting drug users in Europe following a reported increase of cases in Greece and Romania, 2011

Pharris, Anastasia; Wiessing, L.; Sfetcu, O.; Hedrich, D.; Botescu, A.; Fotiou, Anastasios; Nikolopoulos, Georgios K.; Malliori-Minerva, Melpomeni; Salminen, M.; Suk, J. E.; Griffiths, P.; Laar, M. J. van de (2011)

Greece and Romania reported an increased number of HIV cases among injecting drug users (IDUs) during 2011. Most European countries reported no changes in the rate of newly diagnosed cases of HIV or HIV prevalence in IDUs; ...

Article

Pharmacodynamics of non-break weekly paclitaxel (Taxol) and pharmacokinetics of Cremophor-EL vehicle: Results of a dose-escalation study

Briassoulis, E. Ch; Karavasilis, V.; Tzamakou, E.; Haidou, C.; Piperidou, C.; Pavlidis, Nicholas (2002)

We characterized the toxicity and determined the maximum tolerated dose of non-break weekly paclitaxel (Taxol) in chemotherapy-naive cancer patients, and studied pharmacokinetics of the formulation vehicle Cremophor-EL ...

Article

Validation study of a conventional enzyme immunoassay to detect HIV antibodies in oral fluid

Staneková, D.; Mirandola, M.; Gios, L.; Botsi, Chryssoula; Habekova, M.; Gonzales-Soler, V.; Nikolopoulos, Georgios K. (2016)

OBJECTIVES: The aim of our study was to validate the Genscreen HIV 1/2 version 2 (BIO-RAD) for detecting HIV antibodies in oral fluid specimens (OF). BACKGROUND: The advantage of assays to detect HIV infection in OF lies ...

Conference Object

Symptoms of peripheral neuropathy in Idiopathic Parkinson s Disease: prevalence and impact on quality of life

Unknown author

Article

Near-absolute expression of the bcl-2 protein identifies a subgroup of stage II breast cancer patients with a most favorable outcome. Results of a clinicopathological study

Briassoulis, E. Ch; Agnantis, Niki J.; Zagorianakou, P.; Kamina, S.; Gorezi, M.; Pavlidis, Nicholas; Bai, M. C. (2001)

The clinical relevance of quantitative assessment of tumor-tissue expression of the bcl-2 protein in operated stage II breast cancer was investigated in this study. Thirty-five cases were studied by immunohistochemistry ...

Article

Gemcitabine plus pegylated liposomal doxorubicin in patients with advanced epithelial ovarian cancer resistant/refractory to platinum and/or taxanes. A HeCOG phase II study

Skarlos, Dimosthenis V.; Kalofonos, H. P.; Fountzilas, George; Dimopoulos, M. A.; Pavlidis, Nicholas; Razi, E. D.; Economopoulos, T.; Pectasides, Dimitrios; Gogas, H.; Kosmidis, Paraskevas A.; Bafaloukos, Dimitrios; Klouvas, G. D.; Kyratzis, G.; Aravantinos, Gerasimos (2005)

Background: A phase II study was conducted to evaluate the efficacy and toxicity of the combination of gemcitabine (GEM) and pegylated liposomal doxorubicin (PLD) in patients with platinum- and/or taxane-resistant/refractory ...

Article

A retrospective analysis of serum CA 15-3 concentrations in patients with localised or metastatic renal cancer and its impact on prognosis and follow-up. A single-centre experience

Briassoulis, E. Ch; Pentheroudakis, George; Letsa, I.; Pavlidis, Nicholas (2002)

Background. Monitoring patients with renal cancer for recurrence or progression is ineffective, inconvenient and costly. We conducted a retrospective analysis of serum CA 15-3 concentrations in a single-centre patient ...

Article

The fate of new fosfamides in phase III studies in advanced soft tissue sarcoma

Constantinidou, Anastasia; Graaf, W. T. A. van der (2017)

For decades, doxorubicin alone or in combination with ifosfamide has been used in advanced soft tissue sarcoma (STS). In 2014, a comparison of doxorubicin alone versus the combination with ifosfamide (in the randomised ...

Article

Anthracycline-based chemotherapy of primary non-Hodgkin's lymphoma of the testis: The Hellenic Cooperative Oncology Group experience

Pectasides, Dimitrios; Economopoulos, T.; Kouvatseas, G.; Antoniou, A.; Zoumbos, Z.; Aravantinos, Gerasimos; Tsatalas, C.; Halikia, A.; Nikolaides, C.; Kiamouris, Ch; Pappa, E.; Pavlidis, Nicholas; Skarlos, Dimosthenis V.; Fountzilas, George; Dimopoulos, M. A. (2000)

Testicular non-Hodgkin's lymphoma is an uncommon disease and its outcome following chemotherapy and/or radiotherapy has been variable. A retrospective analysis was performed on 26 patients with primary testicular lymphoma ...

Article

Advanced stage clear-cell epithelial ovarian cancer: The Hellenic cooperative oncology group experience

Pectasides, Dimitrios; Fountzilas, George; Aravantinos, Gerasimos; Kalofonos, H. P.; Efstathiou, E.; Farmakis, D.; Skarlos, Dimosthenis V.; Pavlidis, Nicholas; Economopoulos, T.; Dimopoulos, M. A. (2006)

Purpose.: Ovarian clear-cell carcinomas (OCCC) are known to be possibly resistant to platinum-based chemotherapy and to have a poorer prognosis with respect to other subtypes of epithelial ovarian cancer (EOC). This study ...

Article

Cancer of unknown primary origin

Briassoulis, E. Ch; Pavlidis, Nicholas (1997)

About 3 % of all cancer patients suffer from cancer of unknown primary origin. These patients present with metastatic disease for which a primary site cannot be detected at the time of diagnosis. Sophisticated diagnostic ...

Article

Megestrol acetate in cancer patients with anorexia and weight loss a hellenic co-operative oncology group (heCOG) study

Skarlos, Dimosthenis V.; Fountzilas, George; Pavlidis, Nicholas; Beer, M.; Makrantonakis, P.; Aravantinos, Gerasimos; Pantelakos, P.; Tsavaris, N.; Karpasitis, N.; Kosmidis, Paraskevas A. (1993)

Fifty-two patients with hormone-independent cancer, who complained of anorexia and of weight loss with at least 10% received megestrol acetate (MA), 480 mg daily, during 1-21 weeks. of the 41 patients treated during 4 weeks ...

Article

Systemic therapy in clear cell sarcoma.

Constantinidou, Anastasia; Jones, Robin Lewis; Al-Muderis, Omar; Thway, K.; Ashley, Sue; Scurr, Michelle R.; D'Adamo, David R.; Keohan, Mary Louise; Maki, Robert G.; Judson, Ian Robert (2010)

Article

Glufosfamide administered using a 1-hour infusion given as first-line treatment for advanced pancreatic cancer. A phase II trial of the EORTC-new drug development group

Briassoulis, E. Ch; Pavlidis, Nicholas; Terret, C.; Bauer, J.; Fiedler, W.; Schöffski, P.; Raoul, J. L.; Hess, D.; Selvais, R.; Lacombe, D.; Bachmann, P.; Fumoleau, P. (2003)

The activity of glufosfamide (β-D-glucopyranosyl-N,N′ -di-(2-chloroethyl)-phosphoric acid diamide) against pancreatic cancer was investigated in a multicentre, phase II clinical study. Chemotherapy-naïve patients with ...

Article

Host immune response in sepsis due to ventilator-associated pneumonia: How is it different?

Christaki, Eirini (2009)

Current evidence regarding potentially different host response mechanisms in sepsis according to the type of initiating infection is sporadic. It is possible that alterations in cell populations, variations in effector ...

Article

Informational needs of patients with melanoma and their views on the utility of investigative tests

Constantinidou, Anastasia; Afuwape, S. A.; Linsell, L.; Hung, T.; Acland, Katharine M.; Healy, Ciaran; Ramirez, A. J.; Harries, Mark (2009)

Background: The aim of the study was to identify the informational needs of patients with melanoma on disease status and prognosis, and to ascertain their views on the utility of positron emission tomography (PET) and ...

Book Chapter

Clinical presentation of desmoid tumors

Constantinidou, Anastasia; Scurr, Michelle R.; Judson, Ian Robert; Litchman, C. (Springer, 2012)

Desmoid tumors (DT) constitute a rare fibroblastic proliferative disease. They present sporadically or as a manifestation of a hereditary syndrome such as Familial Adenomatous Polyposis (FAP). Despite the absence of ...