Ιατρική Σχολή / Medical School: Recent submissions

Αποτελέσματα 81-100 από 1246

    • Article  

      Restless legs syndrome in Multiple Sclerosis patients: a contributing factor for fatigue, impaired functional capacity, and diminished health-related quality of life 

      Giannaki, Christoforos D.; Aristotelous, Panagiotis; Stefanakis, Manos; Hadjigeorgiou, Georgios M.; Manconi, Mauro; Leonidou, Eleni; Sakkas, Giorgos K.; Pantzaris, Marios (2018)
      Objectives Restless legs syndrome (RLS) symptoms are common in Multiple Sclerosis (MS) patients. The aim of the current study was to examine for the first time whether RLS could affect the functional capacity and various ...
    • Article  

      Adherence to Mediterranean Diet Reduces Incident Frailty Risk: Systematic Review and Meta-Analysis 

      Kojima, Gotaro; Avgerinou, Christina; Iliffe, Steve; Walters, Kate (2018)
      OBJECTIVES: To conduct a systematic review of the literature on prospective cohort studies examining associations between adherence to a Mediterranean diet and incident frailty and to perform a meta-analysis to synthesize ...
    • Article  

      CpG Island Methylation Patterns in Relapsing-Remitting Multiple Sclerosis 

      Sokratous, Maria; Dardiotis, Efthimios; Bellou, Eleni; Tsouris, Zisis; Michalopoulou, Amalia; Dardioti, Maria; Siokas, Vasileios; Rikos, Dimitrios; Tsatsakis, Aristidis; Kovatsi, Leda; Bogdanos, Dimitrios P.; Hadjigeorgiou, Georgios M. (2018)
      DNA methylation may predispose to multiple sclerosis (MS), as aberrant methylation in the promoter regions across the genome seems to underlie several processes of MS. We have currently determined the methylation status ...
    • Article  

      Associations between the Mediterranean diet and sleep in the elderly 

      Mamalaki, Eirini; Anastasiou, Costas; Kosmidis, Mary; Dardiotis, Efthimios; Hadjigeorgiou, Giorgos; Sakka, Paraskevi; Scarmeas, Nikolaos; Yannakoulia, Mary (2018)
    • Article  

      The cortical excitability profile of patients with the G209A SNCA mutation versus patients with sporadic Parkinson's disease: A transcranial magnetic stimulation study 

      Kimiskidis, Vasilios K.; Papayiannopoulos, Sotirios; Sotirakoglou, Kyriaki; Karakasis, Haralambos; Katsarou, Zoe; Kazis, Dimitrios A.; Papaliagkas, Vasileios; Gatzonis, Stylianos; Papadimitriou, Alexandros; Hadjigeorgiou, Georgios; Bostanjopoulou, Sevasti (2018)
      Mutations in the α-synuclein gene are a rare cause of Parkinson's disease. We investigated, by single-pulse TMS, the cortical excitability profile of nine α-synuclein patients in comparison with 24 idiopathic PD patients, ...
    • Article  

      Intravenous thrombolysis for acute ischemic stroke in Greece: the Safe Implementation of Thrombolysis in Stroke registry 15-year experience: 

      Tsivgoulis, Georgios; Kargiotis, Odysseas; Rudolf, Jobst; Komnos, Apostolos; Tavernarakis, Antonios; Karapanayiotides, Theodoros; Ellul, John; Katsanos, Aristeidis H.; Giannopoulos, Sotirios; Gryllia, Maria; Safouris, Apostolos; Papamichalis, Panagiotis; Vadikolias, Konstantinos; Mitsias, Panayiotis; Hadjigeorgiou, Georgios (2018)
      Background: Intravenous thrombolysis (IVT) remains the only approved systemic reperfusion treatment for acute ischemic stroke (AIS), however there are scarce da...
    • Article  

      Genetic polymorphisms in amyotrophic lateral sclerosis: Evidence for implication in detoxification pathways of environmental toxicants 

      Dardiotis, Efthimios; Siokas, Vasileios; Sokratous, Maria; Tsouris, Zisis; Michalopoulou, Amalia; Andravizou, Athina; Dastamani, Metaxia; Ralli, Styliani; Vinceti, Marco; Tsatsakis, Aristidis; Hadjigeorgiou, Georgios M. (2018)
    • Article  

      Differential effects of completed and incomplete pregnancies on the risk of Alzheimer disease 

      Jang, Hyesue; Bae, Jong Bin; Dardiotis, Efthimios; Scarmeas, Nikolaos; Sachdev, Perminder S.; Lipnicki, Darren M.; Han, Ji Won; Kim, Tae Hui; Kwak, Kyung Phil; Kim, Bong Jo; Kim, Shin Gyeom; Kim, Jeong Lan; Moon, Seok Woo; Park, Joon Hyuk; Ryu, Seung-Ho; Youn, Jong Chul; Lee, Dong Young; Lee, Dong Woo; Lee, Seok Bum; Lee, Jung Jae; Jhoo, Jin Hyeong; Yannakoulia, Mary; Kosmidis, Mary H.; Hadjigeorgiou, Giorgos M.; Sakka, Paraskevi; Kim, Ki Woong (2018)
      OBJECTIVE: To investigate the effects of completed pregnancy with childbirth and incomplete pregnancy without childbirth on the late-life cognition and the risk of Alzheimer disease (AD) in women. METHODS: Using the pooled ...
    • Article  

      Percutaneous patent foramen ovale closure for secondary stroke prevention: Network meta-analysis 

      Tsivgoulis, Georgios; Katsanos, Aristeidis H.; Mavridis, Dimitris; Frogoudaki, Alexandra; Vrettou, Agathi-Rosa; Ikonomidis, Ignatios; Parissis, John; Deftereos, Spyridon; Karapanayiotides, Theodore; Palaiodimou, Lina; Filippatou, Angeliki; Perren, Fabienne; Hadjigeorgiou, Georgios; Alexandrov, Anne W.; Mitsias, Panayiotis D.; Alexandrov, Andrei V. (2018)
      OBJECTIVE: Current guidelines report no benefit for patent foramen ovale (PFO) closure compared to medical treatment in patients with cryptogenic ischemic stroke (IS) or TIA. Two recent randomized controlled clinical trials ...
    • Article  

      SPECT and PET imaging in Alzheimer's disease 

      Valotassiou, Varvara; Malamitsi, Julia; Papatriantafyllou, John; Dardiotis, Efthimios; Tsougos, Ioannis; Psimadas, Dimitrios; Alexiou, Sotiria; Hadjigeorgiou, George; Georgoulias, Panagiotis (2018)
      Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the most common cause of dementia. Beta-amyloid (Aβ) deposition and neurofibrillary tangles (NFTs) of abnormal hyperphosphorylated tau protein are ...
    • Article  

      Commentary on: Comparing the efficacy of disease-modifying therapies in multiple sclerosis 

      Tsivgoulis, Georgios; Katsanos, Aristeidis H.; Voumvourakis, Konstantinos; Hadjigeorgiou, Georgios M.; Heliopoulos, Ioannis; Karapanayiotides, Theodore; Papathanasopoulos, Panagiotis; Kilidireas, Constantinos; Grigoriadis, Nikolaos (2018)
    • Article  

      Associations between the mediterranean diet and sleep in older adults: Results from the hellenic longitudinal investigation of aging and diet study 

      Mamalaki, Eirini; Anastasiou, Costas A.; Ntanasi, Eva; Tsapanou, Angeliki; Kosmidis, Mary H.; Dardiotis, Efthimios; Hadjigeorgiou, Giorgos M.; Sakka, Paraskevi; Scarmeas, Nikolaos; Yannakoulia, Mary (2018)
      18: 1543-1548.
    • Article  

      Prevalence and Risk Factors of Frailty in a Community-Dwelling Population: The HELIAD Study 

      Ntanasi, E.; Yannakoulia, M.; Mourtzi, N.; Vlachos, G. S.; Kosmidis, M. H.; Anastasiou, C. A.; Dardiotis, E.; Hadjigeorgiou, Georgios; Megalou, M.; Sakka, P.; Scarmeas, N. (2020)
      Objective: To estimate the prevalence of frailty using five different instruments in a cohort of older adults and explore the association between frailty and various risk factors. Method: 1,867 participants aged 65 years ...
    • Article  

      Neuroimaging and clinical outcomes of oral anticoagulant-associated intracerebral hemorrhage 

      von der Brelie, Christian; Hadjigeorgiou, Georgios (2018)
      84:702-712.
    • Article  

      Sleep and subjective cognitive decline in cognitively healthy elderly: Results from two cohorts 

      Tsapanou, Angeliki; Vlachos, Georgios S.; Cosentino, Stephanie; Gu, Yian; Manly, Jennifer J.; Brickman, Adam M.; Schupf, Nicole; Zimmerman, Molly E.; Yannakoulia, Mary; Kosmidis, Mary H.; Dardiotis, Efthimios; Hadjigeorgiou, Georgios; Sakka, Paraskevi; Stern, Yaakov; Scarmeas, Nikolaos; Mayeux, Richard (2019)
      Subjective cognitive decline may reflect a dementia prodrome or modifiable risk factor such as sleep disturbance. What is the association between sleep and subjective cognitive decline? Cross-sectional design, from two ...
    • Article  

      Mediterranean diet adherence is related to reduced probability of prodromal Parkinson's disease 

      Maraki, Maria I.; Yannakoulia, Mary; Stamelou, Maria; Stefanis, Leonidas; Xiromerisiou, Georgia; Kosmidis, Mary H.; Dardiotis, Efthimios; Hadjigeorgiou, Georgios M.; Sakka, Paraskevi; Anastasiou, Costas A.; Simopoulou, Eleni; Scarmeas, Nikolaos (2019)
      Background The International Parkinson and Movement Disorder Society recently introduced a methodology for probability score calculation for prodromal PD. Objectives To assess the probability of prodromal PD in an older ...
    • Article  

      Long-term effects of prolonged-release fampridine in cognitive function, fatigue, mood and quality of life of MS patients: The IGNITE study 

      Bakirtzis, C.; Konstantinopoulou, E.; Langdon, D. W.; Grigoriadou, E.; Minti, F.; Nikolaidis, I.; Boziki, M. K.; Tatsi, T.; Ioannidis, P.; Karapanayiotides, T.; Afrantou, T.; Hadjigeorgiou, Georgios M.; Grigoriadis, N. (2018)
      BACKGROUND: Studies have reported conflicting results regarding the potential benefit of prolonged release (PR) fampridine in other domains besides walking. Moreover, only a small number of studies have explored long- term ...
    • Article  

      Low-Frequency and Rare-Coding Variation Contributes to Multiple Sclerosis Risk 

      International Multiple Sclerosis Genetics Consortium. Electronic address: chris.cotsapas@yale.edu; Hadjigeorgiou, Giorgos (2018)
      Multiple sclerosis is a complex neurological disease, with ∼20% of risk heritability attributable to common genetic variants, including >230 identified by genome-wide association studies. Multiple strands of evidence suggest ...
    • Article  

      AQP4 tag SNPs in patients with intracerebral hemorrhage in Greek and Polish population 

      Dardiotis, Efthimios; Siokas, Vasileios; Marogianni, Chrysa; Aloizou, Athina-Maria; Sokratous, Maria; Paterakis, Konstantinos; Dardioti, Maria; Grigoriadis, Savas; Brotis, Alexandros; Kapsalaki, Eftychia; Fountas, Kostas; Jagiella, Jeremiasz; Hadjigeorgiou, Georgios M. (2019)
      BACKROUND: A relatively small number of genetic variants are implicated to pathophysiology of intracerebral hemorrhage (ICH). Aquaporin-4 (AQP4) has been reported to be implicated in the pathophysiological processes of ICH ...
    • Article  

      BDNF rs6265 (Val66Met) Polymorphism as a Risk Factor for Blepharospasm 

      Siokas, Vasileios; Kardaras, Dimitrios; Aloizou, Athina-Maria; Asproudis, Ioannis; Boboridis, Konstadinos G.; Papageorgiou, Eleni; Hadjigeorgiou, Georgios M.; Tsironi, Evangelia E.; Dardiotis, Efthimios (2019)
      A few genetic variants are implicated in the development of blepharospasm (BSP). The precise role of the rs6265 on the brain-derived neurotrophic factor (BDNF) gene on BSP remains controversial. The effect of rs6265 on BSP ...