Ιατρική Σχολή / Medical School: Recent submissions
Now showing items 821-840 of 1246
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Article
Molecular subtypes of gastrointestinal stromal tumors and their prognostic and therapeutic implications
(2017)Gastrointestinal stromal tumors (GISTs) are composed of various molecular subtypes, with differing prognostic and predictive relevance. Previously, tumors lacking mutations in the KIT and PDGFRA genes have been designated ...
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Clinicopathological features and management of hepatic vascular tumors. A 20-year experience in a Greek University Hospital
(2013)Purpose: The aim of this study was to review the clini cal features, diagnostic modalities, treatment options anc pathological characteristics of various types of hepatic vascular tumors treated in our Institution over the ...
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Article
Does psychological distress vary between younger and older adults in health and disease?
(2012)Objective: The effect of age on psychological distress remains controversial and it is unclear how a chronic medical illness influences this association. We aimed to compare the level of psychological distress between ...
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Docetaxel (Taxotere™), a novel taxoid, in the treatment of advanced colorectal carcinoma: An EORTC Early Clinical Trials Group Study
(1994)Docetaxel (Taxotere), a new semisynthetic taxoid, is a potentially important chemotherapeutic agent for the treatment of cancer. Forty patients with bidimensionally measurable advanced adenocarcinoma of the colon were ...
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Multifocal retroperitoneal sarcoma
(2013)Introduction. Retroperitoneal sarcomas comprise a small proportion of all soft tissue sarcomas, and multiple factors influence their clinical behavior. Histopathological type and grade as well as complete surgical resection ...
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[Testicular microlithiasis and Leydig cell proliferation in Wistar rats underwent Fowler-Stephens procedure].
(2012)The present study investigates the outcome of Fowler-Stephens operation in prepubertal Wistar rats focused on microlithiasis and Leydig cell hyperplasia development. Thirty-eight (38) animals underwent laparoscopic ...
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A novel laparoscopic pulse oximeter device. An easy, efficient and cost-effective way of detecting arterial structures
(2010)The introduction of laparoscopy has revolutionized surgery. However, these new techniques have brought new problems into the surgical field. Due to the loss of depth and tactile sensation, time-consuming efforts must bemade ...
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p53/MDM-2 immunohistochemical expression correlated with proliferative activity in different subtypes of human sarcomas: A ten-year follow-up study
(1998)The aim of this study was the evaluation of p53/MDM-2 protein overexpression in different subtypes of human sarcomas, and their correlation with proliferative activity and patient outcome. We selected 40 cases of human ...
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Promising novel therapeutic approaches in the management of gastrointestinal stromal tumors
(2017)Primary and secondary resistance to currently available licensed tyrosine kinase inhibitors poses a real clinical challenge in the management of advanced gastrointestinal stromal tumors. Within the frame of early phase ...
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Neuroendocrine carcinoma of unknown primary: A systematic review of the literature and a comparative study with other neuroendocrine tumors
(2011)Introduction: Neuroendocrine carcinomas of unknown primary (NCUP) represent a specific subset with relatively favorable prognosis. Data on biology, management and outcome of NCUP patients have not been systematically ...
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Insights into the epithelial mesenchymal transition phenotype in cancer of unknown primary from a global microRNA profiling study
(2014)Purpose: We sought to study the microRNA regulation of epithelial mesenchymal transition (EMT), the acquisition of migratory, mesenchymal-like properties of epithelial cells, in cancer of unknown primary (CUP). Patients ...
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Bilateral intralobar pulmonary sequestration in a newborn, case report and review of the literature on bilateral pulmonary sequestrations
(2007)We describe a rare case of bilateral intralobar pulmonary sequestration in a newborn with both sequestrations vascularized from a vessel arising from the celiac trunk of the abdominal aorta. The larger sequestration on the ...
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Outcome of Fowler-Stephens operation for undescended testes: An experimental study
(2007)The aim of this study was the outcome of Fowler-Stephens (FS) operations in prepubertal Wistar rats. Thirty-two 30-day-old rats underwent laparoscopic FS procedures on the right testicles (8 of them formed the control ...
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Survival and disease-progression benefits with treatment regimens for advanced colorectal cancer: a meta-analysis
(2007)Background: Many randomised trials have compared different systemic treatment regimens in patients with advanced colorectal cancer. While survival advances have apparently been achieved, the magnitude of these incremental ...
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Endometrioid Carcinoma of the Prostate. The Diagnostic Value of Leu7 and Prostatic Specific Antigen
(1993)Summary— In a case of endometrioid carcinoma of the prostate the expression of Leu7 and prostatic specific antigen (PSA) was studied immunohistochemically on paraffin sections. The same markers were studied in 14 cases of ...
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Rapid Decline in HIV Incidence among Persons Who Inject Drugs during a Fast-Track Combination Prevention Program after an HIV Outbreak in Athens
(2017)Background. A "seek-test-treat" intervention (ARISTOTLE) was implemented in response to an outbreak of human immunodeficiency virus (HIV) infection among persons who inject drugs (PWID) in Athens. We assess trends in HIV ...
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Management of retroperitoneal sarcomas: Main prognostic factors for local recurrence and survival
(2012)Purpose: Retroperitoneal sarcomas (RPs) are characterized by slow indolent growth and metastasize at a late point in their natural course. The purpose of this study was to review our experience in the management of RSs and ...
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Fertility in female patients with thalassemia
(1998)With recent therapeutic advances, thalassemic patients can now reach adulthood and attain reproductive capacity. Endocrine complications due to hemosiderosis and especially hypogonatotropic hypogonadism, which present ...