Prognostic variables in Greek patients with stage II breast cancer: A Hellenic Cooperative Oncology Group Study
Date
1997Author
Fountzilas, GeorgeVasilaros, S.
Koukouras, D.
Malamos, N.
Pectasides, Dimitrios
Adamou, A.
Nenopoulou, E.
Kiriakou, K.
Zouvani, I.
Katsohis, C.
Kappas, A. M.
Skopa, C.
Semoglou, C.
Fahantidis, E.
Konstantaras, C.
Vasilaki, E.
Economopoulos, T.
Bacoyiannis, Charalambos
Bafaloukos, Dimitrios
Razi, E. D.
Polichrnis, A.
Androulakis, G.
Papaioannou, T.
Pavlidis, Nicholas
Skarlos, Dimosthenis V.
Kosmidis, Paraskevas A.
Source
Anticancer ResearchVolume
17Issue
6 DPages
4681-4689Google Scholar check
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Show full item recordAbstract
The independent effects of several patient, tumor and treatment-related prognostic factors on relapse-free survival (RFS) and overall survival (OS) were assessed by Cox multivariate regression analysis in 988 Greek patients with stage II breast cancer. At a median follow-up time of 83 (range 3.3-131+) months and after the evaluation of all patients together, the number of positive axillary nodes (p < 0.0001), tumor size (p = 0.0024) and tumor grade (p = 0.0008) were identified as significant prognostic factors for RFS. Also, the number of positive nodes (p < 0.0001), tumor size (p = 0.0002) and ER status (p = 0.0001) were found to be significant for OS. These short-term prognostic variables are similar to those reported for this group of patients in other European countries and in the USA.