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dc.contributor.authorPaika, V.en
dc.contributor.authorAlmyroudi, A.en
dc.contributor.authorTomenson, B.en
dc.contributor.authorCreed, F.en
dc.contributor.authorKampletsas, E. O.en
dc.contributor.authorSiafaka, V.en
dc.contributor.authorGkika, S.en
dc.contributor.authorMavreas, V.en
dc.contributor.authorPavlidis, Nicholasen
dc.contributor.authorHyphantis, T.en
dc.creatorPaika, V.en
dc.creatorAlmyroudi, A.en
dc.creatorTomenson, B.en
dc.creatorCreed, F.en
dc.creatorKampletsas, E. O.en
dc.creatorSiafaka, V.en
dc.creatorGkika, S.en
dc.creatorMavreas, V.en
dc.creatorPavlidis, Nicholasen
dc.creatorHyphantis, T.en
dc.date.accessioned2018-06-22T09:54:04Z
dc.date.available2018-06-22T09:54:04Z
dc.date.issued2010
dc.identifier.urihttps://gnosis.library.ucy.ac.cy/handle/7/42175
dc.description.abstractObjective: The aim of the present study was to test whether psychological distress and personality variables are independently associated with health-related quality of life (HRQOL) in colorectal cancer patients, after adjusting for age, gender, education and disease severity. Methods: In a cross-sectional study of 162 colorectal cancer patients (response rate 65.6%), the following self-report instruments were administered: the Symptom Distress Checklist-90-R, the Sense of Coherence scale, the Life Style Index and the Hostility and Direction of Hostility Questionnaire. The outcome measures were the four components of the WHO Quality of Life Instrument, Short Form. We used hierarchical regressions to determine whether psychological distress mediates the relationship of personality and disease parameters with HRQOL. Results: The overall proportion of the variance in the four components of HRQOL explained by our regression models ranged from 28.1 to 44.4%. Psychological distress was an independent correlate of HRQOL, associated with physical (p<0005), mental ( p<0.05) and social relationships HRQOL ( p<0.02). Personality variables were associated with HRQOL independent of psychological distress and disease severity. Sense of coherence and denial defense were positively associated with all aspects of HRQOL independent of psychological distress and disease parameters ( p-values ranging from p<0.05 to p<0.0005). Hostility (p<0.01) and repression defense ( p=0.024) were also independently but negatively associated with physical HRQOL. Conclusions: In colorectal cancer patients, psychological distress is associated with HRQOL independent of disease parameters but personality variables are also associated with HRQOL independent of disease severity and psychological distress, and this could be relevant to psychological interventions. Copyright © 2009 John Wiley & Sons, Ltd.en
dc.language.isoengen
dc.sourcePsycho-oncologyen
dc.subjectStatisticsen
dc.subjectAgeen
dc.subjectAge factorsen
dc.subjectArticleen
dc.subjectPersonalityen
dc.subjectPsychologicalen
dc.subjectGenderen
dc.subjectHumanen
dc.subjectWorld health organizationen
dc.subjectHumansen
dc.subjectAdulten
dc.subjectAgeden
dc.subjectCancer patienten
dc.subjectCross-sectional studiesen
dc.subjectFemaleen
dc.subjectMajor clinical studyen
dc.subjectRegression analysisen
dc.subjectMaleen
dc.subjectColorectal canceren
dc.subjectColorectal neoplasmsen
dc.subjectStressen
dc.subjectDisease severityen
dc.subjectSex factorsen
dc.subjectQuestionnaireen
dc.subjectOncologyen
dc.subjectDistress syndromeen
dc.subjectEducational statusen
dc.subjectHostilityen
dc.subjectSeverity of illness indexen
dc.subjectDefense mechanismsen
dc.subjectEgo mechanisms of defenseen
dc.subjectPsychological distressen
dc.subjectSense of coherenceen
dc.subjectQuality of lifeen
dc.subjectLifestyleen
dc.subjectDefensive behavioren
dc.subjectNonparametricen
dc.subjectPsychological testsen
dc.subjectSelf reporten
dc.titlePersonality variables are associated with colorectal cancer patients' quality of life independent of psychological distress and disease severityen
dc.typeinfo:eu-repo/semantics/article
dc.identifier.doi10.1002/pon.1563
dc.description.volume19
dc.description.issue3
dc.description.startingpage273
dc.description.endingpage282
dc.author.facultyΙατρική Σχολή / Medical School
dc.type.uhtypeArticleen
dc.contributor.orcidPavlidis, Nicholas [0000-0002-2195-9961]
dc.contributor.orcidHyphantis, T. [0000-0002-7647-4312]
dc.gnosis.orcid0000-0002-2195-9961
dc.gnosis.orcid0000-0002-7647-4312


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