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dc.contributor.authorNikolopoulos, Georgios K.en
dc.contributor.authorBagos, Pantelis G.en
dc.contributor.authorLytras, Theodorosen
dc.contributor.authorBonovas, Stefanosen
dc.creatorNikolopoulos, Georgios K.en
dc.creatorBagos, Pantelis G.en
dc.creatorLytras, Theodorosen
dc.creatorBonovas, Stefanosen
dc.date.accessioned2018-06-22T09:54:07Z
dc.date.available2018-06-22T09:54:07Z
dc.date.issued2011
dc.identifier.urihttps://gnosis.library.ucy.ac.cy/handle/7/42198
dc.description.abstractBackground: Pandemic A (H1N1) 2009 mortality rates varied widely from one country to another. Our aim was to identify potential socioeconomic determinants of pandemic mortality and explain between-country variation. Methodology: Based on data from a total of 30 European countries, we applied random-effects Poisson regression models to study the relationship between pandemic mortality rates (May 2009 to May 2010) and a set of representative environmental, health care-associated, economic and demographic country-level parameters. The study was completed by June 2010. Principal Findings: Most regression approaches indicated a consistent, statistically significant inverse association between pandemic influenza-related mortality and per capita government expenditure on health. The findings were similar in univariable [coefficient: -0.00028, 95% Confidence Interval (CI): -0.00046, -0.00010, p = 0.002] and multivariable analyses (including all covariates, coefficient: -0.00107, 95% CI: -0.00196, -0.00018, p = 0.018). The estimate was barely insignificant when the multivariable model included only significant covariates from the univariate step (coefficient: -0.00046, 95% CI: -0.00095, 0.00003, p = 0.063). Conclusions: Our findings imply a significant inverse association between public spending on health and pandemic influenza mortality. In an attempt to interpret the estimated coefficient (-0.00028) for the per capita government expenditure on health, we observed that a rise of 100 international dollars was associated with a reduction in the pandemic influenza mortality rate by approximately 2.8%. However, further work needs to be done to unravel the mechanisms by which reduced government spending on health may have affected the 2009 pandemic influenza mortality. © 2011 Nikolopoulos et al.en
dc.language.isoengen
dc.sourcePLoS ONEen
dc.subjectEuropeen
dc.subjectRegression analysisen
dc.subjectArticleen
dc.subjectYoung adulten
dc.subjectHumanen
dc.subjectHumansen
dc.subjectAdulten
dc.subjectAgeden
dc.subjectFemaleen
dc.subjectMajor clinical studyen
dc.subjectAdolescenten
dc.subjectMaleen
dc.subjectMortalityen
dc.subjectHumanen
dc.subjectInfluenzaen
dc.subjectMiddle ageden
dc.subjectHealth care qualityen
dc.subjectSocioeconomicsen
dc.subjectInfluenzaen
dc.subjectHealth care costen
dc.subjectPoisson distributionen
dc.subject2009 h1n1 influenzaen
dc.subjectEconomic evaluationen
dc.subjectEnvironmental factoren
dc.subjectHealth care accessen
dc.titleAn ecological study of the determinants of differences in 2009 pandemic influenza mortality rates between countries in Europeen
dc.typeinfo:eu-repo/semantics/article
dc.identifier.doi10.1371/journal.pone.0019432
dc.description.volume6
dc.description.issue5
dc.author.facultyΙατρική Σχολή / Medical School
dc.author.departmentΙατρική Σχολή / Medical School
dc.type.uhtypeArticleen
dc.contributor.orcidNikolopoulos, Georgios K.[0000-0002-3307-0246]
dc.contributor.orcidBagos, Pantelis G. [0000-0003-4935-2325]
dc.contributor.orcidBonovas, Stefanos [0000-0001-6102-6579]
dc.gnosis.orcid0000-0002-3307-0246
dc.gnosis.orcid0000-0003-4935-2325
dc.gnosis.orcid0000-0001-6102-6579


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