Browsing Τμήμα Μηχανικών Μηχανολογίας και Κατασκευαστικής / Department of Mechanical and Manufacturing Engineering by Author "Baish, J. W."

Now showing items 1-3 of 3

    • Article  

      Role of vascular normalization in benefit from metronomic chemotherapy 

      Mpekris, F.; Baish, J. W.; Stylianopoulos, T.; Jain, R. K. (2017)
      Metronomic dosing of chemotherapy - defined as frequent administration at lower doses - has been shown to be more efficacious than maximum tolerated dose treatment in preclinical studies, and is currently being tested in ...
    • Article  

      Scaling rules for diffusive drug delivery in tumor and normal tissues 

      Baish, J. W.; Stylianopoulos, T.; Lanning, R. M.; Kamoun, W. S.; Fukumura, D.; Munn, L. L.; Jain, R. K. (2011)
      Delivery of blood-borne molecules and nanoparticles from the vasculature to cells in the tissue differs dramatically between tumor and normal tissues due to differences in their vascular architectures. Here we show that ...
    • Article  

      Towards Optimal Design of Cancer Nanomedicines: Multi-stage Nanoparticles for the Treatment of Solid Tumors 

      Stylianopoulos, T.; Economides, E. A.; Baish, J. W.; Fukumura, D.; Jain, R. K. (2015)
      Conventional drug delivery systems for solid tumors are composed of a nano-carrier that releases its therapeutic load. These two-stage nanoparticles utilize the enhanced permeability and retention (EPR) effect to enable ...