Browsing Τμήμα Μηχανικών Μηχανολογίας και Κατασκευαστικής / Department of Mechanical and Manufacturing Engineering by Author "Koullapis, P. G."
Now showing items 1-8 of 8
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Conference Object
Computational fluid dynamics (CFD) Simulations of aerosol deposition in the lungs
Koullapis, P. G.; Kassinos, Stavros C.; Lin, C.-L. (TSFP-9, 2015)In the current study, Large Eddy Simulations (LES) are used to investigate the transport and deposition of inhaled aerosol particles (dp = 0.1, 0.5, 1, 2.5, 5, 10 μm) in a realistic geometry of the human airways under ...
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Conference Object
The Effect of Flow Rate and Electrostatic Charge on Aerosol Deposition in a Realistic Lung Geometry
Koullapis, P. G.; Kassinos, Stavros C. (Springer International Publishing, 2018)To be able to predict the fate of therapeutic or pollutant xenobiotic inhaled particles in the human lungs, we need to understand the nature of airflow as it occurs throughout the entire respiratory tract.
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Article
The effect of flow rate and electrostatic charge on aerosol deposition in a realistic lung geometry
Koullapis, P. G.; Kassinos, Stavros C. (2018)To be able to predict the fate of therapeutic or pollutant xenobiotic inhaled particles in the human lungs, we need to understand the nature of airflow as it occurs throughout the entire respiratory tract. © 2018, Springer ...
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Article
An efficient computational fluid-particle dynamics method to predict deposition in a simplified approximation of the deep lung
Koullapis, P. G.; Hofemeier, P.; Sznitman, J.; Kassinos, Stavros C. (2018)High-fidelity simulations of the complete airway tree are still largely beyond current computational capabilities. Towards large-scale simulations of the human lung, the current study introduces a numerical methodology to ...
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Article
An efficient computational fluid-particle dynamics method to predict deposition in a simplified approximation of the deep lung
Koullapis, P. G.; Hofemeier, P.; Sznitman, J.; Kassinos, Stavros C. (2018)High-fidelity simulations of the complete airway tree are still largely beyond current computational capabilities. Towards large-scale simulations of the human lung, the current study introduces a numerical methodology to ...
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Article
In silico assessment of mouth-throat effects on regional deposition in the upper tracheobronchial airways
Koullapis, P. G.; Nicolaou, L.; Kassinos, Stavros C. (2018)Regional deposition of inhaled medicines is a valuable metric of effectiveness in drug delivery applications to the lung. In silico methods are now emerging as a valuable tool for the detailed description of localized ...
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Article
In silico assessment of mouth-throat effects on regional deposition in the upper tracheobronchial airways
Koullapis, P. G.; Nicolaou, L.; Kassinos, Stavros C. (2018)Regional deposition of inhaled medicines is a valuable metric of effectiveness in drug delivery applications to the lung. In silico methods are now emerging as a valuable tool for the detailed description of localized ...
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Article
Particle deposition in a realistic geometry of the human conducting airways: Effects of inlet velocity profile, inhalation flowrate and electrostatic charge
Koullapis, P. G.; Kassinos, Stavros C.; Bivolarova, M. P.; Melikov, A. K. (2016)Understanding the multitude of factors that control pulmonary deposition is important in assessing the therapeutic or toxic effects of inhaled particles. The use of increasingly sophisticated in silico models has improved ...