Browsing Τμήμα Μηχανικών Μηχανολογίας και Κατασκευαστικής / Department of Mechanical and Manufacturing Engineering by Author "Papageorgis, Panagiotis"

Now showing items 1-6 of 6

    • Article  

      Activin A Signaling Regulates IL13Rα2 Expression to Promote Breast Cancer Metastasis 

      Kalli, Maria; Mpekris, Fotios; Wong, Chen K.; Panagi, Myrofora; Ozturk, Sait; Thiagalingam, Sam; Stylianopoulos, Triantafyllos; Papageorgis, Panagiotis (2019)
      Metastatic dissemination of cancer cells to distal organs is the major cause of death for patients suffering from the aggressive basal-like breast cancer (BLBC) subtype. Recently, we have shown that interleukin 13 receptor ...
    • Article  

      Depletion of Ras Suppressor-1 (RSU-1) promotes cell invasion of breast cancer cells through a compensatory upregulation of a truncated isoform 

      Gkretsi, Vasiliki; Kalli, Maria; Efstathiades, Christodoulos; Papageorgis, Panagiotis; Papanikolaou, Vassilios; Zacharia, Lefteris C.; Tsezou, Aspasia; Athanassiou, Evangelos; Stylianopoulos, Triantafyllos (2019)
      Extracellular matrix (ECM)-adhesion proteins and actin cytoskeleton are pivotal in cancer cell invasion. Ras Suppressor-1 (RSU-1), a cell-ECM adhesion protein that interacts with PINCH-1, thus being connected to Integrin ...
    • Article  

      Dexamethasone Increases Cisplatin-Loaded Nanocarrier Delivery and Efficacy in Metastatic Breast Cancer by Normalizing the Tumor Microenvironment 

      Martin, John D.; Panagi, Myrofora; Wang, Chenyu; Khan, Thahomina T.; Martin, Margaret R.; Voutouri, Chrysovalantis; Toh, Kazuko; Papageorgis, Panagiotis; Mpekris, Fotios; Polydorou, Christiana; Ishii, Genichiro; Takahashi, Shinichiro; Gotohda, Naoto; Suzuki, Toshiyuki; Wilhelm, Matthew E.; Melo, Vinicio Alejandro; Quader, Sabina; Norimatsu, Jumpei; Lanning, Ryan M.; Kojima, Motohiro; Stuber, Matthew David; Stylianopoulos, Triantafyllos; Kataoka, Kazunori; Cabral, Horacio (2019)
      Dexamethasone is a glucocorticoid steroid with anti-inflammatory properties used to treat many diseases, including cancer, in which it helps manage various side effects of chemo-, radio-, and immunotherapies. Here, we ...
    • Article  

      NAA40 contributes to colorectal cancer growth by controlling PRMT5 expression 

      Demetriadou, Christina; Pavlou, Demetria; Mpekris, Fotios; Achilleos, Charis; Stylianopoulos, Triantafyllos; Zaravinos, Apostolos; Papageorgis, Panagiotis; Kirmizis, Antonis (2019)
      N-alpha-acetyltransferase 40 (NAA40) catalyzes the transfer of an acetyl moiety to the alpha-amino group of serine 1 (S1) on histones H4 and H2A. Our previous studies linked NAA40 and its corresponding N-terminal acetylation ...
    • Article  

      Solid Stress Facilitates Fibroblasts Activation to Promote Pancreatic Cancer Cell Migration 

      Kalli, Maria; Papageorgis, Panagiotis; Gkretsi, Vasiliki; Stylianopoulos, Triantafyllos (2018)
      Pancreatic fibroblasts are continuously gaining ground as an important component of tumor microenvironment that dynamically interact with cancer cells to promote tumor progression. In addition, these tumor-infiltrated ...
    • Article  

      Stress alleviation strategy in cancer treatment: Insights from a mathematical model 

      Mpekris, Fotios; Voutouri, Chrysovalantis; Papageorgis, Panagiotis; Stylianopoulos, Triantafyllos (2018)
      Tumors generate mechanical forces during growth and progression, which are able to compress blood and lymphatic vessels, reducing perfusion rates and creating hypoxia. Tumor vessels—while nourishing the tumor—are usually ...