Browsing Τμήμα Μηχανικών Μηχανολογίας και Κατασκευαστικής / Department of Mechanical and Manufacturing Engineering by Author "Leen, Edward"
Now showing items 1-9 of 9
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Automatic respiratory gating for contrast ultrasound evaluation of liver lesions
Christofides, Damianos; Leen, Edward; Averkiou, Michalakis A. (2014)Dynamic contrast-enhanced ultrasound (DCEUS) has been used in radiology for many years for lesion detection and characterization. In recent years, more emphasis has been placed on tumor perfusion quantification with DCEUS. ...
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Automatic respiratory gating for perfusion quantification of DCEUS
Christofides, Damianos; AVERKIOU, MICHALAKIS A.; Leen, Edward (2013)A novel automatic respiratory gating (ARG) algorithm for ultrasound is presented. The ARG algorithm was applied on dual contrast imaging (contrast/tissue) loops in order to remove respiratory motion artifacts from dynamic ...
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Article
Contrast-enhanced 3D ultrasound in the radiofrequency ablation of liver tumors
Leen, Edward; Kumar, Senthil; Khan, Shahid A.; Low, Gavin; Ong, Keh Oon; Tait, Paul; AVERKIOU, MICHALAKIS A. (2008)Liver metastases and hepatocellular carcinomas are two of the most common causes of cancer deaths in the world. Radiofrequency ablation (RFA) is a well recognized, effective and minimally invasive means of treating malignant ...
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Article
Dynamic contrast enhanced ultrasound assessment of the vascular effects of novel therapeutics in early stage trials
Leen, Edward; AVERKIOU, MICHALAKIS A.; Arditi, Marcel; Burns, Peter; Bokor, Daniela; Gauthier, Thomas; Kono, Yuko; Lucidarme, Olivier (2012)Imaging is key in the accurate monitoring of response to cancer therapies targeting tumour vascularity to inhibit its growth and dissemination. Dynamic contrast enhanced ultrasound (DCE ultrasound) is a quantitative method ...
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Article
Evaluation of Perfusion Quantification Methods with Ultrasound Contrast Agents in a Machine-Perfused Pig Liver
Averkiou, Michalakis; Keravnou, Christina P.; Izamis, Maria Louisa; Leen, Edward (2018)Purpose To evaluate dynamic contrast-enhanced ultrasound (DCEUS) as a tool for measuring blood flow in the macro- and microcirculation of an ex-vivo machine-perfused pig liver and to confirm the ability of DCEUS to accurately ...
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Evaluation of the Accuracy of Liver Lesion DCEUS Quantification With Respiratory Gating
Christofides, Damianos; Leen, Edward; AVERKIOU, MICHALAKIS A. (2016)Confidence in the accuracy of dynamic contrast enhanced ultrasound (DCEUS) quantification parameters is imperative for the correct diagnosis of liver lesion perfusion characteristics. An important source of uncertainty in ...
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Article
Improvement of the accuracy of liver lesion DCEUS quantification with the use of automatic respiratory gating
Christofides, Damianos; Leen, Edward; Averkiou, Michalakis A.; Leen, Edward L. S.; Averkiou, Michalakis A. (2016)Objectives: To evaluate the efficiency of automatic respiratory gating (ARG) in reducing respiratory motion-induced artefacts from dynamic contrast-enhanced ultrasound (DCEUS) acquisitions and to assess the impact of ARG ...
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Original Contribution: Quantification of Tumor Microvascularity with Respiratory Gated Contrast Enhanced Ultrasound for Monitoring Therapy
Averkiou, Michalakis A.; Lampaskis, Marios; Kyriakopoulou, Konstantina; Skarlos, Dimosthenis; Klouvas, Georgios; Strouthos, Costas; Leen, Edward (2010)The aim of this feasibility study was to evaluate the response to cytotoxic and antiangiogenic treatment of colorectal liver metastasis using respiratory gated contrast enhanced ultrasonography. Seven patients were monitored ...
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Article
Quantification of Tumor Microvascularity with Respiratory Gated Contrast Enhanced Ultrasound for Monitoring Therapy
Averkiou, Michalakis A.; Lampaskis, Marios; Kyriakopoulou, Konstantina; Skarlos, Dimosthenis; Klouvas, Georgios; Strouthos, Costas; Leen, Edward (2010)Abstract: The aim of this feasibility study was to evaluate the response to cytotoxic and antiangiogenic treatment of colorectal liver metastasis using respiratory gated contrast enhanced ultrasonography. Seven patients ...