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The Solid Mechanics of Cancer and Strategies for Improved Therapy
(2017)
Tumor progression and response to treatment is determined in large part by the generation of mechanical stresses that stem from both the solid and the fluid phase of the tumor. Furthermore, elevated solid stress levels can ...
Mechanical stress regulates tissue oxygenation, cancer cell proliferation and drug delivery during progression of solid tumors
(Springer Verlag, 2016)
Oxygen supply plays a central role in cancer cell proliferation. While vascular density increases at the early stages of carcinogenesis, mechanical solid stresses developed during growth compress tumor blood vessels and, ...
Stress-mediated progression of solid tumors: effect of mechanical stress on tissue oxygenation, cancer cell proliferation, and drug delivery
(2015)
Oxygen supply plays a central role in cancer cell proliferation. While vascular density increases at the early stages of carcinogenesis, mechanical solid stresses developed during growth compress tumor blood vessels and, ...
Evolution of osmotic pressure in solid tumors
(2014)
The mechanical microenvironment of solid tumors includes both fluid and solid stresses. These stresses play a crucial role in cancer progression and treatment and have been analyzed rigorously both mathematically and ...
Rapid shear of initially anisotropic turbulence in a rotating frame?
(2007)
In the present study, we investigate, using inviscid rapid distortion theory, the evolution of sheared turbulence in a rotating frame as a function of the rotation rate (including stable, transitional, and unstable regimes), ...
Numerical simulation of injection mold filling for semi-solid materials
(ASME, 1995)
Processing of metals and metal matrix composites in the semi-solid state is an emerging new technology and is becoming increasingly popular. This method provides several advantages over the traditional liquid state processing ...