Brain MR image normalization in texture analysis of multiple sclerosis
SourceFinal Program and Abstract Book - 9th International Conference on Information Technology and Applications in Biomedicine, ITAB 2009
9th International Conference on Information Technology and Applications in Biomedicine, ITAB 2009
Google Scholar check
MetadataShow full item record
A problem that occurs in texture analysis and quantitative analysis of magnetic resonance imaging (MRI), is that the extracted results are not comparable between consecutive or repeated scans or, within the same scan, between different anatomic regions. The reason is that there are intra-scan and inter-scan image intensity variations due to the MRI instrumentation. Therefore, image intensity normalization methods should be applied to magnetic resonance (MR) images prior to further image analysis. The objective of this work was to investigate six different MRI intensity normalization methods and propose the most appropriate for the pre-processing of brain T2-weighted MR images acquired from 22 symptomatic untreated multiple sclerosis (MS) subjects and 10 healthy volunteers. Following image normalization, texture analysis was carried out in original and normalized images for normal appearing white matter (NAMW) and MS lesions, detected in transverse T2weighted MR images. The best normalization method (Histogram Normalization (HN)) demonstrated a smaller Kullback Leibler divergence (0.05, 0.06) suggesting appropriateness for pre-processing MR images used in texture analysis of MS brain lesions. This is a prerequisite step in the assessment of texture features as surrogate markers of disease progression. ©2009 IEEE.
Showing items related by title, author, creator and subject.
Kaplanis, P. A.; Pattichis, Constantinos S.; Hadjileontiadis, L. J.; Roberts, V. C. (2009)The objective of this study was to compute reference SEMG values for normal subjects of 13 parameters extracted in the time, frequency and bispectrum domain, from the Biceps Brachii (BB) muscle generated under isometric ...
Aristokleous, Nicolas; Seimenis, Ioannis; Georgiou, Georgios C.; Nicolaïdes, Andrew N.; Anayiotos, Andreas S. (2015)The geometric and hemodynamic characteristics of the left and right vertebral arteries (LVA, RVA) of six healthy volunteers were investigated for the supine (S) and the prone position (P) a common sleeping posture with ...
Huang, M.; Caines, P. E.; Charalambous, Charalambos D.; Malhamé, R. P. (2001)This paper considers power control for log-normal fading channels. A rate based power set point control model and an associated performance measure are introduced. Within this framework, a unique stochastic optimal power ...