dc.contributor.author | Batsala, G. K. | en |
dc.contributor.author | Dokorou, Vaso N. | en |
dc.contributor.author | Kourkoumelis, Nikolaos | en |
dc.contributor.author | Manos, Manolis J. | en |
dc.contributor.author | Tasiopoulos, Anastasios J. | en |
dc.contributor.author | Mavromoustakos, Thomas M. | en |
dc.contributor.author | Simčič, M. | en |
dc.contributor.author | Golič-Grdadolnik, S. | en |
dc.contributor.author | Hadjikakou, Sotiris K. | en |
dc.creator | Batsala, G. K. | en |
dc.creator | Dokorou, Vaso N. | en |
dc.creator | Kourkoumelis, Nikolaos | en |
dc.creator | Manos, Manolis J. | en |
dc.creator | Tasiopoulos, Anastasios J. | en |
dc.creator | Mavromoustakos, Thomas M. | en |
dc.creator | Simčič, M. | en |
dc.creator | Golič-Grdadolnik, S. | en |
dc.creator | Hadjikakou, Sotiris K. | en |
dc.date.accessioned | 2019-11-21T06:16:49Z | |
dc.date.available | 2019-11-21T06:16:49Z | |
dc.date.issued | 2012 | |
dc.identifier.uri | http://gnosis.library.ucy.ac.cy/handle/7/55284 | |
dc.description.abstract | Direct reaction of copper(I) chloride with 2-mercaptopyrimidine (pmtH) in the presence of the triphenylphosphine (tpp) in 1:1:2 M ratio forms the mixed ligand Cu(I) complex with formula [CuCl(tpp) 2(pmtH)] (1). The dimeric {[Cu(tpp)(pmt)] 2 0.5(MeOH)} (2) complex was derived from the reaction of 1 with twofold molar amount of sodium hydroxide. However, the reaction of copper(II) sulfate or nitrate with pmtH and tpp in 1:2:2 M ratio, unexpectedly results in the formation of the [CuSH(tpp) 2(pmtH)] (3) complex. Further studies have shown that the [Cu(tpp) 2(pmt)] (4) complex is formed by reacting copper(II) acetate with pmtH in the presence of tpp in 1:2:2 M ratio, while in the absent of tpp, the Cu(CH 3COO) 2 or CuSO 4 is found to oxidizes pmtH to its corresponding disulfide (pmt) 2. For comparison the mixed ligand silver(I) chloride or nitrate complexes with formula [AgCl(tpp) 2(pmtH)] (5) or [Ag(NO 3)(tpp) 2(pmtH)] (6) are also synthesized by reacting of the AgCl or AgNO 3 with pmtH and tpp in 1:2:2 M ratio. The complexes have been characterized by elemental analyses, m.p., vibrational spectroscopy (mid-, far-FT-IR and Raman), 1H NMR, UV-Vis, ESI-MS, TG-DTA spectroscopic techniques and single crystal X-ray crystallography at ambient conditions. Photolysis of 1-6, was also studied and the results showed formation of triphenylphosphine oxide. The complexes 1-6, were used to study their influence upon the catalytic peroxidation of the linoleic acid by the enzyme lipoxygenase (LOX) experimentally and theoretically. The binding of 1-4 with LOX was also investigated by saturation transfer difference 1H NMR experiments (STD). © 2011 Elsevier B.V. All rights reserved. | en |
dc.source | Inorganica Chimica Acta | en |
dc.source.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84857065273&doi=10.1016%2fj.ica.2011.10.024&partnerID=40&md5=8fd7d1e3c39ae7993b7063e911000c12 | |
dc.subject | Photolysis | en |
dc.subject | Crystal structures | en |
dc.subject | Bioinorganic chemistry | en |
dc.subject | Copper(I) complexes | en |
dc.subject | Silver(I) complexes | en |
dc.title | Copper(I)/(II) or silver(I) ions towards 2-mercaptopyrimidine: An exploration of a chemical variability with possible biological implication | en |
dc.type | info:eu-repo/semantics/article | |
dc.identifier.doi | 10.1016/j.ica.2011.10.024 | |
dc.description.volume | 382 | |
dc.description.issue | 1 | |
dc.description.startingpage | 146 | |
dc.description.endingpage | 157 | |
dc.author.faculty | 002 Σχολή Θετικών και Εφαρμοσμένων Επιστημών / Faculty of Pure and Applied Sciences | |
dc.author.department | Τμήμα Χημείας / Department of Chemistry | |
dc.type.uhtype | Article | en |
dc.description.notes | <p>Cited By :15</p> | en |
dc.source.abbreviation | Inorg.Chim.Acta | en |
dc.contributor.orcid | Tasiopoulos, Anastasios J. [0000-0002-4804-3822] | |
dc.contributor.orcid | Hadjikakou, Sotiris K. [0000-0001-9556-6266] | |
dc.contributor.orcid | Mavromoustakos, Thomas M. [0000-0001-5309-992X] | |
dc.gnosis.orcid | 0000-0002-4804-3822 | |
dc.gnosis.orcid | 0000-0001-9556-6266 | |
dc.gnosis.orcid | 0000-0001-5309-992X | |