dc.contributor.author | Emayan, K. | en |
dc.contributor.author | English, R. F. | en |
dc.contributor.author | Koutentis, Panayiotis Andreas | en |
dc.contributor.author | Rees, C. W. | en |
dc.creator | Emayan, K. | en |
dc.creator | English, R. F. | en |
dc.creator | Koutentis, Panayiotis Andreas | en |
dc.creator | Rees, C. W. | en |
dc.date.accessioned | 2019-11-21T06:18:59Z | |
dc.date.available | 2019-11-21T06:18:59Z | |
dc.date.issued | 1997 | |
dc.identifier.issn | 0300-922X | |
dc.identifier.uri | http://gnosis.library.ucy.ac.cy/handle/7/55471 | |
dc.description.abstract | 4,5-Dichloro-1,2,3-dithiazolium chloride 1 condenses with active methylene compounds, such as malononitrile, barbituric acid and Meldrum's acid, to give the dithiazol-5-ylidene derivatives, such as 3,4 and 5, in modest yields. Better yields are obtained from 4-chloro-1,2,3-dithiazole-5-thione 6. Thus the thione 6 condenses with diphenyldiazomethane in a very mild version of the Barton double extrusion synthesis of hindered alkenes | en |
dc.description.abstract | this requires neither heat to extrude nitrogen nor a phosphine to abstract sulfur, to give the alkene 7 (83%) (Scheme 1). This alkene rearranges at room temperature, with loss of hydrogen chloride and sulfur, to give the benzothiophene 13 (89%) in a new thiophene ring-forming reaction (Scheme 2). The thione 6 also condenses with tetracyanoethylene oxide to give a better yield of the dicyanomethylene compound 3 (70%) (Scheme 4). Compound 3, in turn, reacts with morpholine and with chloride ions (Scheme 5) to give 3-morpholino- 19 (60%) and 3-chloro- 20 (100%) isothiazole-4,5-dicarbonitrile, in a new isothiazole ring synthesis. Mechanisms are proposed for all of these reactions. | en |
dc.source | Journal of the Chemical Society - Perkin Transactions 1 | en |
dc.source.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-33748737718&partnerID=40&md5=399b3dcb868d5617b5864ec1e805234a | |
dc.title | New routes to benzothiophenes, isothiazoles and 1,2,3-dithiazoles | en |
dc.type | info:eu-repo/semantics/article | |
dc.description.issue | 22 | |
dc.description.startingpage | 3345 | |
dc.description.endingpage | 3349 | |
dc.author.faculty | 002 Σχολή Θετικών και Εφαρμοσμένων Επιστημών / Faculty of Pure and Applied Sciences | |
dc.author.department | Τμήμα Χημείας / Department of Chemistry | |
dc.type.uhtype | Article | en |
dc.description.notes | <p>Cited By :37</p> | en |
dc.contributor.orcid | Koutentis, Panayiotis Andreas [0000-0002-4652-7567] | |
dc.gnosis.orcid | 0000-0002-4652-7567 | |