dc.contributor.author | Kalogirou, Andreas S. | en |
dc.contributor.author | Koutentis, Panayiotis Andreas | en |
dc.creator | Kalogirou, Andreas S. | en |
dc.creator | Koutentis, Panayiotis Andreas | en |
dc.date.accessioned | 2019-11-21T06:19:40Z | |
dc.date.available | 2019-11-21T06:19:40Z | |
dc.date.issued | 2016 | |
dc.identifier.uri | http://gnosis.library.ucy.ac.cy/handle/7/55617 | |
dc.description.abstract | The reactivity of 3,5-dichloro-4H-1,2,6-thiadiazine 4,4-ketals towards nucleophilic substitution or palladium-catalyzed C–C coupling at the C-3/5 positions led to seven new 3,5-disubstituted 4H-1,2,6-thiadiazine ethylene glycol 4,4-ketals and seven 3,5-disubstituted 4H-1,2,6-thiadiazine catechol 4,4-ketals in 83–98% yields. Furthermore, 3,5-diphenyl-4H-1,2,6-thiadiazine ethylene glycol and catechol 4,4-ketals were successfully hydrolysed in conc. H2SO4at 20 °C to afford 3,5-diphenyl-4H-1,2,6-thiadiazin-4-one in 74% and 89% yields. © 2016 Elsevier Ltd | en |
dc.source | Tetrahedron letters | en |
dc.source.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84976871374&doi=10.1016%2fj.tetlet.2016.06.055&partnerID=40&md5=95881af39ea006209365b81dc87a55b3 | |
dc.subject | unclassified drug | en |
dc.subject | Article | en |
dc.subject | chemical structure | en |
dc.subject | chemical bond | en |
dc.subject | catalyst | en |
dc.subject | palladium | en |
dc.subject | Nucleophilic aromatic substitution | en |
dc.subject | nucleophilicity | en |
dc.subject | substitution reaction | en |
dc.subject | hydrolysis | en |
dc.subject | thiadiazine derivative | en |
dc.subject | 3,5 dichloro 4h 1,2,6 thiadiazine 4,4 ketal | en |
dc.subject | 3,5 diphenyl 4h 1,2,6 thiadiazine ethylene glycol | en |
dc.subject | C–C coupling | en |
dc.subject | catechol | en |
dc.subject | catechol 4,4 ketal | en |
dc.subject | cross coupling reaction | en |
dc.subject | Heterocyclic chemistry | en |
dc.subject | Protecting groups | en |
dc.title | Substitution chemistry of 3,5-dichloro-4H-1,2,6-thiadiazine 4,4-ketals | en |
dc.type | info:eu-repo/semantics/article | |
dc.identifier.doi | 10.1016/j.tetlet.2016.06.055 | |
dc.description.volume | 57 | |
dc.description.issue | 30 | |
dc.description.startingpage | 3307 | |
dc.description.endingpage | 3310 | |
dc.author.faculty | 002 Σχολή Θετικών και Εφαρμοσμένων Επιστημών / Faculty of Pure and Applied Sciences | |
dc.author.department | Τμήμα Χημείας / Department of Chemistry | |
dc.type.uhtype | Article | en |
dc.description.notes | <p>Cited By :2</p> | en |
dc.source.abbreviation | Tetrahedron Lett. | en |
dc.contributor.orcid | Koutentis, Panayiotis Andreas [0000-0002-4652-7567] | |
dc.contributor.orcid | Kalogirou, Andreas S. [0000-0002-5476-5805] | |
dc.gnosis.orcid | 0000-0002-4652-7567 | |
dc.gnosis.orcid | 0000-0002-5476-5805 | |