| dc.contributor.author | Keramidas, Anastasios D. | en |
| dc.contributor.author | Maltezou, E. | en |
| dc.contributor.author | Stylianou, Marios | en |
| dc.contributor.author | Roy, S. | en |
| dc.contributor.author | Drouza, Chryssoula | en |
| dc.creator | Keramidas, Anastasios D. | en |
| dc.creator | Maltezou, E. | en |
| dc.creator | Stylianou, Marios | en |
| dc.creator | Roy, S. | en |
| dc.creator | Drouza, Chryssoula | en |
| dc.date.accessioned | 2019-11-21T06:19:53Z | |
| dc.date.available | 2019-11-21T06:19:53Z | |
| dc.date.issued | 2010 | |
| dc.identifier.issn | 1565-3633 | |
| dc.identifier.uri | http://gnosis.library.ucy.ac.cy/handle/7/55665 | |
| dc.description.abstract | Bisphosphonates are biologically relevant therapeutics for bone disorders and cancer. Reaction of γ-chlorobutyric acid, phosphorus acid, and phosphorus trichloride without the use of solvent gave the tetrahydrofuranyl-2, 2-bisphosphonate sodium salt (Na2H2L). The Na 2H2L was isolated, characterized in solution by 1H, 13C, and 31P NMR spectroscopy and in solid state by single X-Ray crystallography. The crystal structure showed that the Na2H2L forms in the crystal infinite two-dimensional sheets stacked one parallel to the other. A comparison of the chelating properties of H2L2- with similar hydroxyl bisphosphonate ligands shows that the strength of the NaO(furanyl/hydroxyl) bond is directly related to the total charge of the ligand anion. Copyright © 2010 Elena Maltezou et al. | en |
| dc.source | Bioinorganic Chemistry and Applications | en |
| dc.source.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-77953508425&doi=10.1155%2f2010%2f563875&partnerID=40&md5=55a338cf64f2de561d36445aa5660fc0 | |
| dc.title | Synthesis, solution, and structural characterization of tetrahydrofuranyl-2,2-bisphosphonic acid disodium salt | en |
| dc.type | info:eu-repo/semantics/article | |
| dc.identifier.doi | 10.1155/2010/563875 | |
| dc.description.volume | 2010 | |
| dc.author.faculty | 002 Σχολή Θετικών και Εφαρμοσμένων Επιστημών / Faculty of Pure and Applied Sciences | |
| dc.author.department | Τμήμα Χημείας / Department of Chemistry | |
| dc.type.uhtype | Article | en |
| dc.description.notes | <p>Cited By :2</p> | en |
| dc.source.abbreviation | Bioinorg.Chem.Appl. | en |
| dc.contributor.orcid | Keramidas, Anastasios D. [0000-0002-0446-8220] | |
| dc.contributor.orcid | Drouza, Chryssoula [0000-0002-2630-4323] | |
| dc.gnosis.orcid | 0000-0002-0446-8220 | |
| dc.gnosis.orcid | 0000-0002-2630-4323 | |
