dc.contributor.author | Michaelidou, Sophia S. | en |
dc.contributor.author | Koutentis, Panayiotis Andreas | en |
dc.creator | Michaelidou, Sophia S. | en |
dc.creator | Koutentis, Panayiotis Andreas | en |
dc.date.accessioned | 2019-11-21T06:21:28Z | |
dc.date.available | 2019-11-21T06:21:28Z | |
dc.date.issued | 2009 | |
dc.identifier.uri | http://gnosis.library.ucy.ac.cy/handle/7/55852 | |
dc.description.abstract | 2-(4-Chloro-5H-1,2,3-dithiazolylideneamino)benzonitrile 1a reacts with triphenylphosphine (4 equiv) in the presence of water (2 equiv) to afford anthranilonitrile 2a, 3-aminoindole-2-carbonitrile 3a and (2-cyanoindol-3-yl)iminotriphenylphosphorane 4a, together with triphenylphosphine sulfide and oxide. The use of polymer bound triphenylphosphine provides cleaner reaction mixtures. 2-(4-Chloro-5H-1,2,3-dithiazolylideneamino)-4,5-dimethoxybenzonitrile 1h does not give the corresponding indole on treatment with triphenylphosphine but gives 6,7-dimethoxyquinazoline-2-carbonitrile 5 (15%) and 2-cyano-4,5-dimethoxy cyanothioformanilide 6 (36%). A total of seven new 3-aminoindole-2-carbonitriles 3a-g are prepared and fully characterised. © 2009 Elsevier Ltd. All rights reserved. | en |
dc.source | Tetrahedron | en |
dc.source.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-69249173341&doi=10.1016%2fj.tet.2009.07.064&partnerID=40&md5=e82fd38a27ae900303d02a097b5e9544 | |
dc.subject | article | en |
dc.subject | priority journal | en |
dc.subject | unclassified drug | en |
dc.subject | nitrile | en |
dc.subject | oxide | en |
dc.subject | chemical reaction | en |
dc.subject | proton nuclear magnetic resonance | en |
dc.subject | water | en |
dc.subject | indole derivative | en |
dc.subject | mass spectrometry | en |
dc.subject | carbon nuclear magnetic resonance | en |
dc.subject | thiazole derivative | en |
dc.subject | triphenylphosphine | en |
dc.subject | cyanide | en |
dc.subject | (2 cyanoindol 3 yl)iminotriphenylphosphorane | en |
dc.subject | 3 aminoindole 2 carbonitrile derivative | en |
dc.subject | 6,7 dimethoxyquinazoline 2 carbonitrile | en |
dc.subject | anthranilonitrile | en |
dc.subject | benzonitrile | en |
dc.subject | 2 (4 chloro 5h 1,2,3 dithiazolylideneamino)benzonitrile | en |
dc.subject | 2 cyano 4,5 dimethoxycyanothioformanilide | en |
dc.subject | microanalysis | en |
dc.subject | phosphorane derivative | en |
dc.subject | phosphorus nuclear magnetic resonance | en |
dc.subject | quinazoline derivative | en |
dc.title | The conversion of 2-(4-chloro-5H-1,2,3-dithiazolylideneamino)benzonitriles into 3-aminoindole-2-carbonitriles using triphenylphosphine | en |
dc.type | info:eu-repo/semantics/article | |
dc.identifier.doi | 10.1016/j.tet.2009.07.064 | |
dc.description.volume | 65 | |
dc.description.issue | 40 | |
dc.description.startingpage | 8428 | |
dc.description.endingpage | 8433 | |
dc.author.faculty | 002 Σχολή Θετικών και Εφαρμοσμένων Επιστημών / Faculty of Pure and Applied Sciences | |
dc.author.department | Τμήμα Χημείας / Department of Chemistry | |
dc.type.uhtype | Article | en |
dc.description.notes | <p>Cited By :15</p> | en |
dc.source.abbreviation | Tetrahedron | en |
dc.contributor.orcid | Koutentis, Panayiotis Andreas [0000-0002-4652-7567] | |
dc.gnosis.orcid | 0000-0002-4652-7567 | |