Addition of tetraethylthiuram disulfide to antimony(III) iodide
Synthesis, characterization and biological activity
dc.contributor.author | Urgut, O. S. | en |
dc.contributor.author | Ozturk, I. I. | en |
dc.contributor.author | Banti, Christina N. | en |
dc.contributor.author | Kourkoumelis, Nikolaos | en |
dc.contributor.author | Manoli, Maria | en |
dc.contributor.author | Tasiopoulos, Anastasios J. | en |
dc.contributor.author | Hadjikakou, Sotiris K. | en |
dc.creator | Urgut, O. S. | en |
dc.creator | Ozturk, I. I. | en |
dc.creator | Banti, Christina N. | en |
dc.creator | Kourkoumelis, Nikolaos | en |
dc.creator | Manoli, Maria | en |
dc.creator | Tasiopoulos, Anastasios J. | en |
dc.creator | Hadjikakou, Sotiris K. | en |
dc.date.accessioned | 2019-11-21T06:23:26Z | |
dc.date.available | 2019-11-21T06:23:26Z | |
dc.date.issued | 2016 | |
dc.identifier.uri | http://gnosis.library.ucy.ac.cy/handle/7/56265 | |
dc.description.abstract | Three new antimony(III) iodide complexes with the N,N-diethylcarbamodithioic acid of formulae {[(SbI(Et2DTC)2)(I2)]n} (1), {[(Sb(Et2DTC)2)4 (SbI6) (I3)]n} (2) and {[SbI(Et2DTC)2]2} (3), (Et2DTCH: N,N-diethylcarbamodithioic acid, C5H11NS2) were synthesized from the reaction of antimony(III) iodide with tetraethylthiuram disulfide in 1:1 stoichiometry. The complexes 1-3 were characterized by melting point, elemental analysis, FT-IR spectroscopy, Raman spectroscopy, 1H, 13C NMR spectroscopy and Thermal Gravimetry-Differential Thermal Analysis (TG-DTA). Moreover, crystal structures of complexes 1-3 were determinated with single crystal X-ray diffraction analysis. Complexes 1-3 derived from ligand reduction with concomitant degradation of the tetraethylthiuram disulfide to dithiocarbamates. Complexes 1 and 2 are polymer but complex 3 is dimmer. Complex 1 consists of two residues, [SbI(Et2DTC)2] and [I2], while 2 consists of three residues, four cationic [Sb(Et2dtc)2]+, one [SbI6]3- and one [I3]- counter anion. Complexes 1-3 were evaluated for their in vitro cytotoxic activity against human breast adenocarcinoma (MCF-7) and human cervix adenocarcinoma (HeLa) cells. Structure Activity Relationship (SAR) studies reveal that the high activity of the complexes is positively correlated with the low H-all atoms intermolecular contacts. © 2016 Published by Elsevier B.V. | en |
dc.source | Inorganica Chimica Acta | en |
dc.source.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84954475947&doi=10.1016%2fj.ica.2015.12.028&partnerID=40&md5=32dcef99223e5186e37728a041224457 | |
dc.subject | Cytotoxicity | en |
dc.subject | Crystal structures | en |
dc.subject | Antimony(III) complexes | en |
dc.subject | N,N-diethylcarbamodithioic acid | en |
dc.subject | Structure Activity Relationship (SAR) | en |
dc.title | Addition of tetraethylthiuram disulfide to antimony(III) iodide | en |
dc.title | Synthesis, characterization and biological activity | en |
dc.type | info:eu-repo/semantics/article | |
dc.identifier.doi | 10.1016/j.ica.2015.12.028 | |
dc.description.volume | 443 | |
dc.description.startingpage | 141 | |
dc.description.endingpage | 150 | |
dc.author.faculty | 002 Σχολή Θετικών και Εφαρμοσμένων Επιστημών / Faculty of Pure and Applied Sciences | |
dc.author.department | Τμήμα Χημείας / Department of Chemistry | |
dc.type.uhtype | Article | en |
dc.description.notes | <p>Cited By :2</p> | en |
dc.source.abbreviation | Inorg.Chim.Acta | en |
dc.contributor.orcid | Tasiopoulos, Anastasios J. [0000-0002-4804-3822] | |
dc.contributor.orcid | Hadjikakou, Sotiris K. [0000-0001-9556-6266] | |
dc.gnosis.orcid | 0000-0002-4804-3822 | |
dc.gnosis.orcid | 0000-0001-9556-6266 |
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