A correlative study of quantitative EMG and biopsy findings in 31 patients with myopathies
Ημερομηνία
2011Συγγραφέας
Dardiotis, EfthymiosPapathanasiou, Eleftherios Stelios
Vonta, Filia
Hadjigeorgiou, Georgios M.
Zamba-Papanicolaou, Eleni
Kyriakides, Theodoros
ISSN
1128-2460Source
Acta MyologicaVolume
30Issue
JUNEPages
37-41Google Scholar check
Keyword(s):
Metadata
Εμφάνιση πλήρους εγγραφήςΕπιτομή
A direct correlation of QEMG with muscle biopsy findings might help delineate the sensitivity of QEMG in identifying muscle pathology as well as provide information on electrophysiological-histological correlations. In a study of 31 patients with a variety of myopathies we found that the sensitivity of QEMG was between 24 to 69% depending of the specific method of signal analysis. The positive predictive value of abnormal QEMG was more than 90% while its negative predictive value was only about 20%. Amplitude outlier analysis was superior especially in minimally weak muscles (MRC > 4) and was particularly sensitive at detecting increased variability in fiber size and more subtle myopathic changes.