dc.contributor.author | Zissimou, Georgia A. | en |
dc.contributor.author | Kourtellaris, Andreas | en |
dc.contributor.author | Koutentis, Panayiotis A. | en |
dc.creator | Zissimou, Georgia A. | en |
dc.creator | Kourtellaris, Andreas | en |
dc.creator | Koutentis, Panayiotis A. | en |
dc.date.accessioned | 2021-01-25T09:44:46Z | |
dc.date.available | 2021-01-25T09:44:46Z | |
dc.date.issued | 2018 | |
dc.identifier.uri | http://gnosis.library.ucy.ac.cy/handle/7/63017 | |
dc.description.abstract | Treating 1-fluoro-2-nitrobenzene (6) with N′-pentafluorophenylbenzohydrazide (7) and K2CO3 (1.1 equiv) in EtOH at ca. 110 °C (sealed tube) for 24 h affords 5,6,7,8-tetrafluoro-1-(2-nitrophenyl)-3-phenyl-1H-benzo[e][1,3,4]oxadiazine (5) (36%) and N′-(2-nitrophenyl)-N′-(perfluorophenyl)benzohydrazide (3) (37%). The X-ray crystallography of 5,6,7,8-tetrafluoro-1-(2-nitrophenyl)-3-phenyl-1H-benzo[e][1,3,4]oxadiazine (5) is provided. Microwave irradiation (100 W) of perfluorophenylbenzohydrazide 3 with K2CO3 (1.1 equiv) in THF at ca. 120 °C (sealed tube, 80 PSI) for 3 h gives oxadiazine 5 (85%), while reduction of the nitro group using Sn (4 equiv) in glacial acetic acid at ca. 20 °C for 30 min, followed by cyclodehydration at ca. 118 °C for 20 min and treatment with 2 M NaOH for 24 h resulted in 1-(perfluorophenyl)-3-phenyl-1,2,4-benzotriazin-4-yl (4) with 93% yield. | en |
dc.language.iso | en | en |
dc.source | Molbank | en |
dc.source.uri | https://www.mdpi.com/1422-8599/2018/2/M997 | |
dc.title | 5,6,7,8-Tetrafluoro-1-(2-nitrophenyl)-3-phenyl-1H-benzo[e][1,3,4]oxadiazine | en |
dc.type | info:eu-repo/semantics/article | |
dc.identifier.doi | 10.3390/M997 | |
dc.description.volume | 2018 | |
dc.description.issue | 2 | |
dc.author.faculty | 002 Σχολή Θετικών και Εφαρμοσμένων Επιστημών / Faculty of Pure and Applied Sciences | |
dc.author.department | Τμήμα Χημείας / Department of Chemistry | |
dc.type.uhtype | Article | en |
dc.contributor.orcid | Zissimou, Georgia A. [0000-0003-4821-9469] | |
dc.contributor.orcid | Koutentis, Panayiotis A. [0000-0002-4652-7567] | |
dc.gnosis.orcid | 0000-0003-4821-9469 | |
dc.gnosis.orcid | 0000-0002-4652-7567 | |