Browsing by Subject "Cholesterol"
Now showing items 1-14 of 14
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Article
Are the effects of tamoxifen on the serum lipid profile modified by apolipoprotein E phenotypes?
(2002)Background: Tamoxifen has favorable effects on the serum lipid profile. It has been suggested that the apolipoprotein (Apo) E phenotype can influence serum lipid parameters; the ApoE allele 4 (ApoE4) is associated with ...
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Conference Object
Assessment of the risk of coronary heart event based on data mining
(2008)Coronary heart disease (CHD) is a major cause of morbidity and mortality in the western world. Although significant progress has been made in the diagnosis and treatment of CHD, further investigation is still needed. The ...
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Article
The association between plasminogen activator inhibitor type 1 (PAI-1) levels, PAI-1 4G/5G polymorphism, and myocardial infarction: A mendelian randomization meta-analysis
(2014)Background: The circulating levels of plasminogen activator inhibitor type 1 (PAI-1) are increased in individuals carrying the 4G allele at position -675 of the PAI-1 gene. In turn, overexpression of PAI-1 has been found ...
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Article
The beneficial effect of tamoxifen on serum lipoprotein-a levels: An additional anti-atherogenic property
(1996)It has recently been suggested that increased lipoprotein (a) levels are an independent risk factor for coronary heart disease. It has also been reported that tamoxifen can induce changes in blood lipid values. In this ...
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Development of a Reliable Analytical Protocol for the Isolation of Cholesterol Oxidation Products—a Comparison of Different Lipid Extraction and Saponification Methods
(2015)The main objectives of this study were (i) the optimization and the validation of a high performance liquid chromatographic method for the simultaneous determination of seven cholesterol oxidation products (COPs), (ii) the ...
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Article
Effect of letrozole on the lipid profile in postmenopausal women with breast cancer
(2001)Hormonal therapy plays a central role in the overall treatment of breast cancer. Aromatase inhibitors can inhibit the aromatase enzyme system resulting in a reduction of oestrogens. Letrozole is a non-steroidal aromatase ...
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Effects of hormonal treatment on lipids in patients with cancer
(2009)Patients with malignant disease may need hormonal therapy as primary or adjuvant treatment or for palliation. Oestrogens usually decrease serum levels of total cholesterol (TC) and low density lipoprotein cholesterol ...
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Article
Metabolic syndrome and its components as predictors of all-cause mortality and coronary heart disease in type 2 diabetic patients
(2007)Background: There is no consistent evidence regarding the prognostic value of metabolic syndrome (MS) in predicting all-cause mortality and coronary heart disease (CHD) risk among type 2 diabetic patients. We sought to ...
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Article
Sample preparation: A critical step in the analysis of cholesterol oxidation products
(2014)In recent years, cholesterol oxidation products (COPs) have drawn scientific interest, particularly due to their implications on human health. A big number of these compounds have been demonstrated to be cytotoxic, mutagenic, ...
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Article
Serotonin and neuron-specific enolase: Serum acute and mid-term levels and their association with posttraumatic depression
(2010)OBJECTIVES: To investigate the association between serotonin (SER), cholesterol, and neuron-specific enolase (NSE) serum levels with depression after traumatic brain injury (TBI). MATERIALS AND METHODS: Seventy-four patients ...
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Article
Tamoxifen-induced severe hypertriglyceridemia and pancreatitis
(2000)Tamoxifen exhibits favorable effects on the lipid and lipoprotein profile since it decreases the total and LDL cholesterol levels as well as the Lp(a) levels. Additionally, a small increase in serum triglycerides is commonly ...
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Doctoral Thesis Open Access
Προσδιορισμός των προϊόντων οξείδωσης της χοληστερόλης στα κυπριακά τρόφιμα με τη χρήση νέων βελτιωμένων αναλυτικών τεχνικών
(Πανεπιστήμιο Κύπρου, Σχολή Θετικών και Εφαρμοσμένων Επιστημών / University of Cyprus, Faculty of Pure and Applied Sciences, 2015-05)Tα προϊόντα οξείδωσης της χοληστερόλης (Cholesterol Oxidation Products, COPs) αποτελούν το ερευνητικό αντικείμενο της παρούσας εργασίας. Αρχικό κίνητρο για τη διενέργεια της συγκεκριμένης διδακτορικής διατριβής ήταν η ...