• Article  

      The effect of the plasminogen activator inhibitor-1 4G/5G polymorphism on the thrombotic risk 

      Tsantes, Argirio E.; Nikolopoulos, Georgios K.; Bagos, Pantelis G.; Bonovas, Stefanos; Kopterides, Petros; Vaiopoulos, G. (2008)
      Plasminogen activator inhibitor (PAI-1), is the central component of the fibrinolytic system. A deletion/insertion (4G/5G) polymorphism in the promoter region of the PAI-1 gene has been correlated with levels of plasma ...
    • Article  

      Media thickness measurement of the common carotid artery. 

      Loizou, Christos P.; Pattichis, Constantinos S.; Pantzaris, Marios C.; Nicolaïdes, Andrew N.; Georgiou, Niki; Kyriacou, Efthyvoulos C. (2007)
      The intima-media thickness (IMT) of the common carotid artery (CCA) is widely used as an early indicator of the development of cardiovascular disease (CVD). It was proposed but not thoroughly investigated that the media ...
    • Article  

      Metabolic syndrome and its components as predictors of ischemic stroke in type 2 diabetic patients 

      Protopsaltis, I. D.; Korantzopoulos, Panagiotis; Milionis, Haralampos J.; Koutsovasilis, Anastasios; Nikolopoulos, Georgios K.; Dimou, Eftihia; Kokkoris, Stelios; Brestas, Paris; Elisaf, Moses S.; Melidonis, Andreas (2008)
      BACKGROUND AND PURPOSE - The available data regarding the association between metabolic syndrome (MS) or MS components and ischemic stroke in type 2 diabetics are limited and inconsistent. This study aimed to investigate ...
    • Article  

      Plasminogen activator inhibitor-1 4G/5G polymorphism and risk of ischemic stroke: A meta-analysis 

      Tsantes, Argirio E.; Nikolopoulos, Georgios K.; Bagos, Pantelis G.; Tsiara, Chrissa G.; Kapsimali, Violetta; Travlou, Anthi S.; Vaiopoulos, G. (2007)
      This study investigated the hypothesis that the insertion/deletion (4G/5G) polymorphism of the plasminogen activator inhibitor type-1 gene affects the risk for ischemic stroke, since results concerning this association ...
    • Article  

      Prediction of high-risk asymptomatic carotid plaques based on ultrasonic image features 

      Kyriacou, Efthyvoulos C.; Petroudi, Styliani; Pattichis, Constantinos S.; Pattichis, Marios S.; Griffin, Maura B.; Kakkos, Stavros K.; Nicolaïdes, Andrew N. (2012)
      Carotid plaques have been associated with ipsilateral neurological symptoms. High-resolution ultrasound can provide information not only on the degree of carotid artery stenosis but also on the characteristics of the ...
    • Conference Object  

      Prediction of the time period of stroke based on ultrasound image analysis of initially asymptomatic carotid plaques 

      Kyriacou, Efthyvoulos C.; Vogazianos, Paris; Christodoulou, Chris C.; Loizou, Christos P.; Panayides, Andreas S.; Petroudi, Styliani; Pattichis, Marios S.; Pantzaris, Marios C.; Nicolaïdes, Andrew N.; Pattichis, Constantinos S. (Institute of Electrical and Electronics Engineers Inc., 2015)
      Non-invasive ultrasound imaging of carotid plaques can provide information on the characteristics of the arterial wall including the size, morphology and texture of the atherosclerotic plaques. Several studies were carried ...
    • Article  

      Serotonin reuptake inhibitor antidepressants (SSRIs) against atherosclerosis 

      Wozniak, Greta; Toska, Aikaterini; Saridi, Maria; Mouzas, Odysseas (2011)
      Selective serotonin reuptake inhibitors (SSRIs) are a class of drug widely used for treatment of mood disorders, including depression and cardiovascular disease. A search for related articles in the PubMed database was ...
    • Article  

      SPECT imaging and cerebrovascular disease 

      Valotassiou, Varvara; Wozniak, Greta; Sifakis, N.; Iliadis, Charalambos; Georgoulias, Panagiotis (2007)
      Many studies promote both diagnostic and prognostic roles for single photon emission computed tomography (SPECT) functional brain imaging in patients with cerebrovascular disease (CVD). SPECT allows in vivo non-invasive ...
    • Article  

      Ultrasound image texture analysis of the intima and media layers of the common carotid artery and its correlation with age and gender 

      Loizou, Christos P.; Pantzaris, Marios C.; Pattichis, Marios S.; Kyriacou, Efthyvoulos C.; Pattichis, Constantinos S. (2009)
      The intima-media thickness (IMT) of the common carotid artery (CCA) is widely used as an early indicator of cardiovascular disease (CVD). It was proposed but not thoroughly investigated that the composition and texture of ...
    • Article  

      Ultrasound imaging in the analysis of carotid plaque morphology for the assessment of stroke 

      Kyriacou, Efthyvoulos C.; Pattichis, Marios S.; Christodoulou, Christodoulos I.; Pattichis, Constantinos S.; Kakkos, Stavros K.; Griffin, Maura B.; Nicolaïdes, Andrew N. (2005)
      The aim of this chapter is to summarise the recent advances in ultrasonic plaque characterisation and to evaluate the efficacy of computer aided diagnosis based on neural and statistical classifiers using as input texture ...