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Browsing by Subject "buffer"

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    • Article  

      Analysis of polyphenols using capillary zone electrophoresis - Determination of the most effective wine sample pre-treatment method 

      Nicolaou, I. N.; Kapnissi‐Christodoulou, Constantina P. (2010)
      A simple CZE method has been developed for the simultaneous determination of eight polyphenolic compounds. The influence of several experimental conditions such as buffer (concentration and pH) and temperature were studied. ...

    • Article  

      Attenuation of drug-stimulated topoisomerase II-DNA cleavable complex formation in wild-type HL-60 cells treated with an intracellular calcium buffer is correlated with decreased cytotoxicity and site-specific hypophosphorylation of topoisomerase IIα 

      Aoyama, M.; Grabowski, D. R.; Dubyak, G. R.; Constantinou, Andreas I.; Rybicki, L. A.; Bukowski, R. M.; Ganapathi, M. K.; Hickson, I. D.; Ganapathi, R. (1998)
      Topoisomerase II (topo II), an essential enzyme for cell viability, is also the target for clinically important anti-neoplastic agents that stimulate topo II-mediated DNA scission. The role of alterations in topo IIα ...

    • Article  

      Evaluation of amino acid ester-based ionic liquids as buffer additives in CE for the separation of 2-arylpropionic acids nonsteroidal anti-inflammatory drugs 

      Mavroudi, Maria C.; Kapnissi‐Christodoulou, Constantina P. (2014)
      The aim of the present study is the CE performance evaluation for the separation of 2-arylpropionic acid nonsteroidal anti-inflammatory drugs. In particular, the separation of indoprofen, carprofen, ketoprofen, ibuprofen, ...

    • Article  

      Molecular factors affecting the complex formation between deferiprone (L1) and Cu(II): Possible implications on efficacy and toxicity 

      Pashalidis, Ioannis; Kontoghiorghes, G. J. (2001)
      Deferiprone (1,2-dimethyl-3-hydroxypyrid-4-one, L1, CAS 30652-11-0) is a new chelating drug used worldwide for the treatment of iron overloading conditions. Spectrophotometric and potentiometric measurements were carried ...

    • Article  

      Open-tubular capillary electrochromatography/electrospray ionization-mass spectrometry using polymeric surfactant as a stationary phase coating 

      Zhu, X.; Kamande, M. W.; Thiam, S.; Kapnissi‐Christodoulou, Constantina P.; Mwongela, S. M.; Warner, I. M. (2004)
      We describe the use of the polymeric surfactant poly(sodium undecylenic sulfate) (poly-SUS) as a stationary phase coating in open-tubular capillary electrochromatog raphy (OT-CEC) coupled with electrospray ionization-mass ...

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