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Gene therapies and their potential application in Type 1 Diabetes
(Πανεπιστήμιο Κύπρου, Σχολή Θετικών και Εφαρμοσμένων Επιστημών / University of Cyprus, Faculty of Pure and Applied Sciences, 2021-05-14)
Type 1 diabetes (T1D) is an autoimmune metabolic disorder, that arises due to autoimmune destruction of the β-cells in the islets of Langerhans in the pancreas. As a result, there is insufficient insulin production and ...
The amyloid hypothesis of Alzheimer’s Disease and its current treatment
(Πανεπιστήμιο Κύπρου, Σχολή Θετικών και Εφαρμοσμένων Επιστημών / University of Cyprus, Faculty of Pure and Applied Sciences, 2020-12-14)
Alzheimer’s disease (AD), a progressive neurodegenerative disorder, is the commonest cause of dementia in the elderly population worldwide. It is a multifactorial disorder, characterized by extracellular β-amyloid peptide ...
The nexus between circRNA and prostate cancer from the complex interventions to treatment expectation
(Πανεπιστήμιο Κύπρου, Σχολή Θετικών και Εφαρμοσμένων Επιστημών / University of Cyprus, Faculty of Pure and Applied Sciences, 2022-05-20)
Circular RNAs (circRNAs) are a kind of RNA that results through a non-regular process known as alternative splicing. Because of their possible regulatory activities during gene expression, circRNAs have lately sparked ...
Molecular mechanisms that Hepatitis B virus uses to induce Hepatocellular Carcinoma
(Πανεπιστήμιο Κύπρου, Σχολή Θετικών και Εφαρμοσμένων Επιστημών / University of Cyprus, Faculty of Pure and Applied Sciences, 2020-12-07)
Hepatitis B is an infectious liver disease caused by the Hepatitis B virus (HBV). HBV is a small DNA virus that mainly affects hepatocytes, which are the main liver cells, and it has the ability to replicate by reverse ...
Adherens Junctions spatially guide ECM deposition by stimulating integrin activation and clustering
(Πανεπιστήμιο Κύπρου, Σχολή Θετικών και Εφαρμοσμένων Επιστημών / University of Cyprus, Faculty of Pure and Applied Sciences, 2022-05-20)
The extracellular matrix (ECM) plays an essential role in all multicellular organisms as a substrate for cell anchorage and tissue scaffolding. It is involved in diverse processes such as cell proliferation and survival, ...