Browsing Τμήμα Βιολογικών Επιστημών / Department of Biological Sciences by Title

Now showing items 316-335 of 677

    • Article  

      The impact of human allelic variation on HIV-1 disease. 

      Anastassopoulou, C. G.; Kostrikis, Leontios G. (2003)
      Human allelic variants influence the susceptibility to HIV-1 infection and/or the subsequent rates of disease progression towards AIDS that average ten years, although they vary greatly among infected subjects. In this ...
    • Article  

      Impact of inflammation on anti‐oxidative effects of vitamin E‐coated membrane dialyzer in patients on chronic hemodialysis 

      Kirmizis, Dimitrios; Papagianni, Aikaterini; Efstratiadis, Georgios; Memmos, Dimitrios (2014)
    • Article  

      Impact of natural chemokine receptor polymorphisms on perinatal transmission of human immunodeficiency virus type 1 

      Kostrikis, Leontios G. (2000)
    • Article  

      Implications of HIV-1 M group polymorphisms on integrase inhibitor efficacy and resistance: Genetic and structural in silico analyses 

      Loizidou, Eriketi Z.; Kousiappa, Ioanna; Zeinalipour-Yazdi, Constantinos D.; Van De Vijver, D. A. M. C.; Kostrikis, Leontios G. (2009)
      The extensive polymorphisms among HIV-1 subtypes have been implicated in drug resistance development. Integrase inhibitors represent the latest addition to the treatment of HIV-1, and their efficacy and resistance patterns ...
    • Article  

      An improved method for the identification of areas of endemism using species co-occurrences 

      Giokas, Sinos; Sfenthourakis, Spyros (2008)
      Aim: To develop a simple method that (1) combines the notions of biotic elements (groups of taxa with ranges significantly more similar to each other than to the ranges of other taxa) and of areas of endemism (AoE, areas ...
    • Article  

      In situ hybridization to determine the expression of peptide neurotransmitters. 

      Santama, Niovi (1997)
    • Article  

      In vitro antioxidant activity and phenolic content of Cedrus brevifolia bark 

      Cretu, E.; Salminen, J. -P; Karonen, M.; Miron, A.; Charalambous, Christina; Constantinou, Andreas I.; Aprotosoaie, A. C. (2014)
      A raw extract and four extractive fractions were obtained from Cedrus brevifolia (Cyprus cedar) bark. They were all studied regarding the phenolic content and profile using spectrophotometry and HPLC-DAD-ESI-MS. The ...
    • Article  

      In vitro study on the antioxidant activity of a polyphenol-rich extract from pinus brutia bark and its fractions 

      Cretu, E.; Karonen, M.; Salminen, J. -P; Mircea, C.; Trifan, A.; Charalambous, Christina; Constantinou, Andreas I.; Miron, A. (2013)
      A crude hydromethanolic extract from Pinus brutia bark and its fractions (diethyl ether, ethyl acetate, n-butanol, and aqueous fractions) were studied with regard to their phenolic content and antioxidant activities. The ...
    • Article  

      In vivo high-resolution magic angle spinning magnetic and electron paramagnetic resonance spectroscopic analysis of mitochondria-targeted peptide in Drosophila melanogaster with trauma-induced thoracic injury 

      Constantinou, Constantina; Apidianakis, Yiorgos; Psychogios, N.; Righi, V.; Mindrinos, M. N.; Khan, N.; Swartz, H. M.; Szeto, H. H.; Tompkins, R. G.; Rahme, L. G.; Aria Tzika, A. (2016)
      Trauma is the most common cause of mortality among individuals aged between 1 and 44 years and the third leading cause of mortality overall in the US. In this study, we examined the effects of trauma on the expression of ...
    • Article  

      In vivo high-resolution magic angle spinning magnetic resonance spectroscopy of Drosophila melanogaster at 14.1 T shows trauma in aging and in innate immune-deficiency is linked to reduced insulin signaling 

      Righi, V.; Apidianakis, Yiorgos; Mintzopoulos, D.; Astrakas, L.; Rahme, L. G.; Tzika, A. A. (2010)
      In vivo magnetic resonance spectroscopy (MRS), a non-destructive biochemical tool for investigating live organisms, has yet to be used in the fruit fly Drosophila melanogaster, a useful model organism for investigating ...
    • Article  

      In vivo high-resolution magic angle spinning proton NMR spectroscopy of Drosophila melanogaster flies as a model system to investigate mitochondrial dysfunction in Drosophila GST2 mutants 

      Righi, V.; Apidianakis, Yiorgos; Psychogios, N.; Rahme, L. G.; Tompkins, R. G.; Tzika, A. A. (2014)
      In vivo nuclear magnetic resonance spectroscopy (NMR), a non-destructive biochemical tool used for investigating live organisms, has recently been performed in studies of the fruit fly Drosophila melanogaster, a useful ...
    • Article  

      In vivo imaging of Drosophila melanogaster pupae with mesoscopic fluorescence tomography 

      Vinegoni, C.; Pitsouli, Chrysoula; Razansky, D.; Perrimon, N.; Ntziachristos, V. (2008)
      We report a technique for fluorescence tomography that operates beyond the penetration limits of tissue-sectioning fluorescence microscopy. The method uses multi-projection illumination and photon transport description in ...
    • Article  

      In vivo imaging of quantum dots encapsulated in phospholipid micelles 

      Dubertret, B.; Skourides, Paris A.; Norris, D. J.; Brivanlou, A. H.; Libchaber, A.; Noireaux, V. (2002)
      Fluorescent semiconductor nanocrystals (quantum dots) have the potential to revolutionize biological imaging, but their use has been limited by difficulties in obtaining nanocrystals that are biocompatible. To address this ...
    • Article  

      In vivo, site-specific, covalent conjugation of quantum dots to proteins via split-intein splicing 

      Charalambous, Anna; Andreou, Maria I.; Antoniades, Ioanna; Christodoulou, Neophytos; Skourides, Paris A. (2012)
      The ability to target proteins with nanostructures and/or nanodevices in vivo is important for understanding and controlling their biological function. Quantum dots (QDs) serve as an ideal model nanostructure due to their ...
    • Article  

      Increase in transmitted resistance to non-nucleoside reverse transcriptase inhibitors among newly diagnosed HIV-1 infections in Europe 

      Moutschen, M.; Frentz, D.; Van de Vijver, D. A. M. C.; Abecasis, A. B.; Albert, Jan; Hamouda, O.; Jørgensen, L. B.; Ku¨cherer, C.; Struck, D.; Schmit, J. -C; Vercauteren, J.; A˚sjo¨, B.; Balotta, Claudia; Beshkov, Danail; Camacho, Ricardo J.; Clotet, B.; Coughlan, S.; Griskevicius, A.; Grossman, Z.; Horban, A.; Kolupajeva, T.; Korn, K.; Kostrikis, Leontios G.; Liitsola, K.; Linka, M.; Nielsen, C.; Otelea, D.; Paraskevis, Dimitrios N.; Paredes, R.; Poljak, M.; Puchhammer, Stockl E.; So¨nnerborg, A.; Stanekova, D.; Stanojevic, M.; Van Wijngaerden, E.; Wensing, A. M. J.; Boucher, C. A. B.; Puchhammer, Stockl E.; Sarcletti, M.; Schmied, B.; Geit, M.; Balluch, G.; Vandamme, A. -M; Vercauteren, J.; Derdelinckx, I.; Sasse, A.; Bogaert, M.; Ceunen, H.; De Roo, A.; De Wit, S.; Echahidi, F.; Fransen, K.; Goffard, J. -C; Goubau, P.; Goudeseune, E.; Yombi, J. -C; Lacor, P.; Liesnard, C.; Pierard, D.; Rens, R.; Schrooten, Y.; Vaira, D.; Vandekerckhove, L. P. R.; Van den Heuvel, A.; Van Der Gucht, B.; Van Ranst, M.; Van Wijngaerden, E.; Vandercam, B.; Vekemans, M.; Verhofstede, C.; Clumeck, N.; Van Laethem, K.; Demetriades, Ioannis; Kousiappa, Ioanna; Demetriou, Victoria L.; Hezka, Johana; Bruckova, M.; Linka, M.; Machala, L.; Nielsen, C.; Jørgensen, L. B.; Gerstoft, J.; Mathiesen, L.; Pedersen, C.; Nielsen, H.; Laursen, A.; Kvinesdal, B.; Salminen, M.; Ristola, M.; Liitsola, K.; Suni, J.; Sutinen, J.; Korn, K.; Ku¨cherer, C.; Berg, T.; Braun, P.; Poggensee, G.; Da¨umer, M.; Eberle, J.; Heiken, H.; Kaiser, R.; Knechten, H.; Mu¨ller, H.; Neifer, S.; Schmidt, B.; Walter, H.; Gunsenheimer-Bartmeyer, B.; Harrer, T.; Paraskevis, Dimitrios N.; Hatzakis, Angelos E.; Magiorkinis, Emmanouil N.; Hatzitheodorou, Eleni; Haida, Catherine; Zavitsanou, Assimina; Magiorkinis, Gkikas; Lazanas, Marios C.; Chini, Maria C.; Magafas, N.; Tsogas, Nickolaos; Paparizos, Vassilios A.; Kourkounti, Sofia; Antoniadou, Anastasia C.; Papadopoulos, Antonios I.; Panagopoulos, Periklis; Poulakou, Garyphallia G.; Sakka, V.; Chryssos, Georgios; Drimis, Stylianos; Gargalianos, Panagiotis; Lelekis, Moyssis I.; Chilomenos, G.; Psichogiou, Mina A.; Daikos, George L.; Panos, George; Haratsis, G.; Kordossis, Theodore; Kontos, Athanasios N.; Koratzanis, Georgios; Theodoridou, Maria C.; Mostrou, Glykeria J.; Spoulou, Vana I.; Coughlan, S.; De Gascun, C.; Byrne, C.; Duffy, M.; Bergin, C.; Reidy, D.; Farrell, G.; Lambert, J.; O'Connor, E.; Rochford, A.; Low, J.; Coakely, P.; O'Dea, S.; Hall, W.; Grossman, Z.; Levi, I.; Chemtob, D.; Balotta, Claudia; Riva, C.; Mussini, C.; Caramma, I.; Capetti, A.; Colombo, M. C.; Rossi, C.; Prati, F.; Tramuto, F.; Vitale, F.; Ciccozzi, M.; Angarano, G.; Rezza, G.; Schmit, J. C.; Struck, D.; Hemmer, R.; Arendt, V.; Staub, T.; Schneider, F.; Roman, F.; Wensing, A. M. J.; Boucher, C. A. B.; Van Kessel, A.; van Bentum, P. H. M.; Brinkman, K.; op de Coul, E. L.; van der Ende, M. E.; Hoepelman, I.; van Kasteren, M.; Juttmann, J.; Kuipers, M.; Langebeek, N.; Richter, C.; Santegoets, R.; Schrijnders-Gudde, L.; Schuurman, R.; van de Ven, B. J. M.; A˚sjo¨, B.; Ormaasen, V.; Aavitsland, P.; Horban, A.; Stanczak, J. J.; Stanczak, G. P.; Firlag-Burkacka, E.; Wiercinska-Drapalo, A.; Jablonowska, E.; Malolepsza, E.; Leszczyszyn-Pynka, M.; Szata, W.; Camacho, Ricardo J.; Palma, C.; Borges, F.; Paixa&tild; o, T.; Duque, V.; Araújo, F.; Jevtovic, D.; Salemovic, D.; Stanekova, D.; Habekova, M.; Mokráš, Miloš; Truska, P.; Poljak, M.; Lunar, M.; Babic, Dunja Z.; Tomazic, J.; Vidmar, L.; Vovko, T.; Karner, P.; Clotet, B.; Domingo, P.; Galindo, M. J.; Miralles, C.; del Pozo, M. A.; Ribera, E.; Iribarren, J. A.; Ruiz, L.; de la Torre, J.; Vidal, F.; Garcia, F.; Paredes, R.; Albert, Jan; Heidarian, A.; Aperia-Peipke, K.; Axelsson, M.; Mild, M.; Karlsson, A.; So¨nnerborg, A.; Thalme, A.; Nave´r, L.; Bratt, G.; Karlsson, A.; Blaxhult, A.; Gissle´n, M.; Svennerholm, B.; Bergbrant, I.; Björkman, Per; Sa¨ll, C.; Mellgren, A˚; Lindholm, A.; Kuylenstierna, N.; Montelius, R.; Azimi, F.; Johansson, B.; Carlsson, M.; Johansson, E.; Ljungberg, B.; Ekvall, H.; Strand, A.; Ma¨kitalo, S.; o¨berg, S.; Holmblad, P.; Ho¨fer, M.; Holmberg, H.; Josefson, P.; Ryding, U. (2014)
      Background: One out of ten newly diagnosed patients in Europe was infected with a virus carrying a drug resistant mutation. We analysed the patterns over time for transmitted drug resistance mutations (TDRM) using data ...
    • Article  

      Increased genetic diversity in Greek populations of the genus Ligidium (Crustacea: Isopoda: Oniscidea) revealed by RFLP analysis of mtDNA segments 

      Klossa-Kilia, E.; Kilias, G.; Sfenthourakis, Spyros (2006)
      We investigated mtDNA genetic differentiation and the phylogenetic relationships of 11 populations of the oniscidean genus Ligidium. We studied nine populations from Greece, assigned to three nominal species (L. euboicum, ...
    • Article  

      Increased molecular divergence of two endemic Trachelipus (Isopoda, Oniscidea) species from Greece reveals patterns not congruent with current taxonomy 

      Parmakelis, A.; Klossa-Kilia, E.; Kilias, G.; Triantis, Kostas A.; Sfenthourakis, Spyros (2008)
      In the present study, we employed three mitochondrial DNA genetic markers in a phylogenetic analysis aiming at the delineation of the relationships amongst nominal Trachelipus kytherensis populations, as well as between ...
    • Article  

      Increased number of MicroRNA target sites in genes encoded in CNV regions. Evidence for an evolutionary genomic interaction 

      Felekkis, Kyriacos N.; Voskarides, Konstantinos; Dweep, H.; Sticht, C.; Gretz, N.; Constantinou-Deltas, Constantinos D. (2011)
      MicroRNAs (miRNAs) and copy number variations (CNVs) are two newly discovered genetic elements that have revolutionized the field of molecular biology and genetics. By performing in silico whole genome analysis, we demonstrate ...
    • Article  

      Induction of caspase-independent programmed cell death by vitamin E natural homologs and synthetic derivatives. 

      Constantinou, Constantina; Hyatt, John Anthony; Vraka, Panayiota S.; Papas, Andreas M.; Papas, Konstantinos A.; Neophytou, Christiana M.; Hadjivassiliou, V.; Constantinou, Andreas I. (2009)
      Current observations in the literature suggest that vitamin E may be a suitable candidate for cancer chemotherapy. To investigate this further, we examined the ability of the vitamin E natural homologs [alpha-, beta-, ...
    • Article  

      Induction of Differentiation and DNA Strand Breakage in Human HL-60 and K-562 Leukemia Cells by Genistein 

      Constantinou, Andreas I.; Kiguchi, K.; Huberman, E. (1990)
      Genistein, an in vitro inhibitor of topoisomerase II and tyrosine kinases, suppressed growth and induced differentiation in HL-205 cells, a clonal population of the human promyelocytic HL-60 leukemia cells, and in K-562-J ...