Browsing Τμήμα Βιολογικών Επιστημών / Department of Biological Sciences by Title
Now showing items 386-405 of 677
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Article
Mesoscopic fluorescence tomography for in-vivo imaging of developing Drosophila.
(2009)Visualizing developing organ formation as well as progession and treatment of disease often heavily relies on the ability to optically interrogate molecular and functional changes in intact living organisms. Most existing ...
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Article
Metabolic output defines Escherichia coli as a health-promoting microbe against intestinal Pseudomonas aeruginosa
(2019)Gut microbiota acts as a barrier against intestinal pathogens, but species-specific protection of the host from infection remains relatively unexplored. Although lactobacilli and bifidobacteria produce beneficial lactic ...
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Article
A metabolite of equine estrogens, 4-hydroxyequilenin, induces DNA damage and apoptosis in breast cancer cell lines
(2000)Estrogen replacement therapy has been correlated with an increased risk of developing breast or endometrial cancer. 4-Hydroxyequilenin (4-OHEN) is a catechol metabolite of equilenin which is a minor component of the estrogen ...
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Book Chapter
Methods of Calpain Inhibition to Determine the Role of Calpains in Embryo Development in Amphibians
(Springer, 2019)Calpains are a family of calcium-dependent intracellular cysteine proteases that regulate important physiological processes by substrate cleavage. Despite the fact that the role of calpains in cell migration and other ...
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Article
MicroRNAs: A newly described class of encoded molecules that play a role in health and disease
(2010)14(4): 236-240.
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Article
A miR-1207-5p binding site polymorphism abolishes regulation of HBEGF and is associated with disease severity in CFHR5 nephropathy
(2012)Heparin binding epidermal growth factor (HBEGF) is expressed in podocytes and was shown to play a role in glomerular physiology. MicroRNA binding sites on the 3′UTR of HBEGF were predicted using miRWalk algorithm and ...
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Article
Mitochondrial sequences of the extinct Cypriot pygmy hippopotamus confirm its phylogenetic placement
(Oxford Academic, 2021-11-19)The Cypriot pygmy hippopotamus is an extinct Mediterranean species that inhabited the island of Cyprus during the Late Pleistocene. This iconic species last appears at the archaeological site of Akrotiri Aetokremnos, dated ...
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Book
Model organisms in inflammation and cancer
(Frontiers Media SA, 2014)
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Article
Model-based tumor growth dynamics and therapy response in a mouse model of de novo carcinogenesis
(2015)Tumorigenesis is a complex, multistep process that depends on numerous alterations within the cell and contribution from the surrounding stroma. The ability to model macroscopic tumor evolution with high fidelity may ...
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Article
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Article
Modelling the role of alien species and fisheries in an Eastern Mediterranean insular shelf ecosystem
(2019)We developed a trophic mass-balance model to describe the structure and functioning of the insular shelf ecosystem of the Republic of Cyprus and assess the impact of fishing and alien species during the mid-2010s. A total ...
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Article
Modification of the enzyme mismatch cleavage method using T7 endonuclease I and silver staining
(2004)
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Article
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Article
Molecular and Clinical Investigation of Cystinuria in the Greek-Cypriot Population
(2015)Background and Aims: Cystinuria represents 3% of nephrolithiasis in humans. Two genes have been identified as the main genetic causes of cystinuria, SLC3A1 and SLC7A9, with an autosomal recessive mode of inheritance. In ...
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Article
Molecular beacon-based real-time PCR detection of primary isolates of salmonella typhimurium and salmonella enteritidis in environmental and clinical samples
(2009)Background. A fast and simple two-step multiplex real-time PCR assay has been developed to replace the traditional, laborious Salmonella serotyping procedure. Molecular beacons were incorporated into the assay as probes ...
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Article
Molecular characterization of HIV type 1 strains from newly diagnosed patients in Cyprus (2007-2009) recovers multiple clades including unique recombinant strains and lack of transmitted drug resistance
(2011)HIV-1 evolution generates substantial genetic diversity among isolates, the majority of which are represented in areas where multiple strains cocirculate. A heterogeneous genetic HIV-1 pool has been found in Cyprus, directing ...
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Conference Object
Molecular clustering via knowledge mining from biomedical scientific corpora
(2013)In this paper, an architecture is presented that allows the extraction of argumentation clauses that might exist in publications, in order to perform molecular clustering on referenced molecules. Grammar rules are defined ...
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Article
Molecular epidemiology of hepatitis C infection in Cyprus within the general population and high-risk cohorts
(2011)Background: Initial data on the molecular epidemiology of HCV infection in Cyprus showed a highly polyphyletic infection and multiple points of introduction into the general population. The continuation and expansion of ...
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Article
Molecular epidemiology of hepatitis C infection in cyprus: Evidence of polyphyletic infection
(2009)The genetic diversity of the hepatitis C virus (HCV) in Cyprus is investigated for the first time in this study. Nucleotide sequence analysis of the CORE-E1 and NS5B regions of the HCV genome was performed on blood plasma ...
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Article
Molecular genetics of familial hematuric diseases
(2013)The familial hematuric diseases are a genetically heterogeneous group of monogenic conditions, caused by mutations in one of several genes. The major genes involved are the following: (i) the collagen IV genes COL4A3/A4/A5 ...