Browsing Τμήμα Βιολογικών Επιστημών / Department of Biological Sciences by Title

Now showing items 494-513 of 677

    • Article  

      PKD2, a gene for polycystic kidney disease that encodes an integral membrane protein 

      Mochizuki, Toshio; Wu, G.; Hayashi, Tomohito; Xenophontos, Stavroulla L.; Veldhuisen, B.; Saris, J. J.; Reynolds, D. M.; Cai, Y.; Gabow, P. A.; Pierides, Alkis M.; Kimberling, W. J.; Breuning, M. H.; Constantinou-Deltas, Constantinos D.; Peters, D. J. M.; Somlo, Stefan (1996)
      A second gene for autosomal dominant polycystic kidney disease was identified by positional cloning. Nonsense mutations in this gene (PKD2) segregated with the disease in three PKD2 families. The predicted 968-amino acid ...
    • Article  

      Point-counterpoint: Soy intake for breast cancer patients 

      Block, K. I.; Constantinou, Andreas I.; Hilakivi-Clarke, L.; Hughes, C.; Tripathy, D.; Tice, J. A. (2002)
    • Article  

      Polarized distribution of Bcr-Abl in migrating myeloid cells and co-localization of Bcr-Abl and its target proteins 

      Skourides, Paris A.; Perera, S. A.; Ren, R. (1999)
      Bcr-Abl plays a critical role in the pathogenesis of Philadelphia chromosome-positive leukemia. Although a large number of substrates and interacting proteins of Bcr-Abl have been identified, it remains unclear whether ...
    • Article  

      The Polycomb Group Protein SUZ12 regulates histone H3 lysine 9 methylation and HP1α distribution 

      De La Cruz, C. C.; Kirmizis, Antonis; Simon, M. D.; Isono, K. -I; Koseki, H.; Panning, B. (2007)
      Regulation of histone methylation is critical for proper gene expression and chromosome function. Suppressor of Zeste 12 (SUZ12) is a requisite member of the EED/EZH2 histone methyltransferase complexes, and is required ...
    • Article  

      A polymorphism in the regulatory region of the CC-chemokine receptor 5 gene influences perinatal transmission of human immunodeficiency virus type 1 to African-American infants 

      Deutsch, L.; Kostrikis, Leontios G.; Neumann, A. U.; Thomson, B.; Korber, B. T.; McHardy, P.; Karanicolas, R.; Huang, Y.; Lew, J. F.; McIntosh, K.; Pollack, H.; Borkowsky, W.; Spiegel, H. M. L.; Palumbo, P.; Oleske, J.; Bardeguez, A.; Luzuriaga, K.; Sullivan, J.; Wolinsky, S. M.; Koup, R. A.; Ho, David D.; Moore, J. P. (1999)
      There are natural mutations in the coding and noncoding regions of the human immunodeficiency virus type (HIV-1) CC-chemokine coreceptor 5 (CCR5) and in the related CCR2 protein (the CCR2-64I mutation). Individuals homozygous ...
    • Article  

      Population density and food analysis of Bombina variegata and Rana graeca in mountainous riverine ecosystems of northern Pindos (Greece) 

      Bisa, Rica; Sfenthourakis, Spyros; Fraguedakis-Tsolis, Stella; Chondropoulos, Basil (ResearchGate, 2007-06-20)
      Abundance and diet of Bombina variegata and Rana graeca were investigated from August 2004to August 2005 in two permanent mountain water bodies (Zesto River and Prioni Nazeti Stream)situated in the National Park of Northern ...
    • Article  

      Post-translational processing of the alternative neuropeptide precursor encoded by the FMRFamide gene in the pulmonate snail Lymnaea stagnalis 

      Santama, Niovi (1996)
    • Article  

      PPredicting bird song from space 

      Smith, Thomas B.; Harrigan, Ryan J.; Kirschel, Alexander N. G.; Buermann, Wolfgang; Saatchi, Sassan; Blumstein, Daniel T.; de, Selvino R.; Slabbekoorn, Hans (2013)
    • Article  

      Predicting bird song from space 

      Smith, T. B.; Harrigan, R. J.; Kirschel, A. N. G.; Buermann, W.; Saatchi, S.; Blumstein, Daniel T.; de Kort, S. R.; Slabbekoorn, H. (2013)
      Environmentally imposed selection pressures are well known to shape animal signals. Changes in these signals can result in recognition mismatches between individuals living in different habitats, leading to reproductive ...
    • Article  

      A preliminary RAPD-PCR analysis of Cimicifuga species and other botanicals used for women's health 

      Xu, H.; Fabricant, D. S.; Piersen, C. E.; Bolton, J. L.; Pezzuto, J. M.; Fong, H.; Totura, S.; Farnsworth, N. R.; Constantinou, Andreas I. (2002)
      Traditional taxonomic methods of botanical identification that rely primarily on morphological observations cannot be used efficiently when only powdered plant materials are available. Thus, our objectives were to determine ...
    • Article  

      Presymptomatic molecular diagnosis of autosomal dominant polycystic kidney disease using PKD1- and PKD2-linked markers in Cypriot families 

      Constantinou-Deltas, Constantinos D.; Christodoulou, Kyproula; Tjakouri, C.; Pierides, Alkis M. (1996)
      Autosomal dominant polycystic kidney disease (ADPKD), is a heterogeneous disorder, primarily characterized by the formation of cysts in the kidneys, and the late development in life of progressive chronic kidney failure. ...
    • Article  

      Prevalence of genetic mutations that predispose to thrombophilia in a Greek Cypriot population 

      Angelopoulou, Katerina; Nicolaïdes, Andrew N.; Constantinou-Deltas, Constantinos D. (2000)
      Several hereditary disorders, particularly those affecting the physiological anticoagulation systems, have been well established as risk factors for venous thromboembolism. In the present study, we investigated the prevalence ...
    • Article  

      Prevention of preneoplastic mammary lesion development by a novel vitamin D analogue, 1α-hydroxyvitamin D5 

      Mehta, R. G.; Moriarty, R. M.; Mehta, R. R.; Penmasta, R.; Lazzaro, G.; Constantinou, Andreas I.; Guo, L. (1997)
      Background: The form of vitamin D (vitamin D3) in fortified milk and the provitamin D produced by the body undergo metabolic activation to a biologically active form, 1α,25-dihydroxyvitamin D3 [1α,25(OH)2D3]. This compound ...
    • Article  

      Primary resistance to integrase strand-transfer inhibitors in Europe 

      Moutschen, M.; Casadellà, M.; van Ham, P. M.; Noguera-Julian, M.; van Kessel, A.; Pou, C.; Hofstra, Laura Marije Arije; Santos, J. R.; Garcia, F.; Struck, D.; Alexiev, Ivailo; Bakken Kran, A. M.; Hoepelman, A. I.; Kostrikis, Leontios G.; Somogyi, Sybille; Liitsola, K.; Linka, M.; Nielsen, C.; Otelea, D.; Paraskevis, Dimitrios N.; Poljak, M.; Puchhammer-Stöckl, E.; Staneková, D.; Stanojevic, M.; Van Laethem, K.; Zidovec Lepej, S.; Clotet, B.; Boucher, C. A. B.; Paredes, R.; Wensing, A. M. J.; Puchhammer-Stöckl, E.; Sarcletti, M.; Schmied, B.; Geit, M.; Balluch, G.; Vandamme, A. M.; Vercauteren, J.; Derdelinckx, I.; Sasse, A.; Bogaert, M.; Ceunen, H.; De Roo, A.; De Wit, S.; Echahidi, F.; Fransen, K.; Goffard, J. C.; Goubau, P.; Goudeseune, E.; Yombi, J. C.; Lacor, P.; Liesnard, C.; Pierard, D.; Rens, R.; Schrooten, Y.; Vaira, D.; Vandekerckhove, L. P.; Van den Heuvel, A.; Van Der Gucht, B.; Van Ranst, M.; Van Wijngaerden, E.; Vandercam, B.; Vekemans, M.; Verhofstede, C.; Clumeck, N.; Van Laethem, K.; Beshkov, Danail; Alexiev, Ivailo; Zidovec Lepej, S.; Begovac, J.; Demetriades, Ioannis; Kousiappa, Ioanna; Demetriou, Victoria L.; Hezka, Johana; Linka, M.; Machala, L.; Maly, M.; Nielsen, C.; Jørgensen, L. B.; Gerstoft, J.; Mathiesen, L.; Pedersen, C.; Nielsen, H.; Laursen, A.; Kvinesdal, B.; Liitsola, K.; Ristola, M.; Suni, J.; Sutinen, J.; Hamouda, O.; Kücherer, C.; Berg, T.; Braun, P.; Poggensee, G.; Däumer, M.; Eberle, J.; Heiken, H.; Kaiser, R.; Knechten, H.; Korn, K.; Müller, H.; Neifer, S.; Schmidt, B.; Walter, H.; Gunsenheimer-Bartmeyer, B.; Harrer, T.; Paraskevis, Dimitrios N.; Hatzakis, Angelos E.; Magiorkinis, Emmanouil N.; Hatzitheodorou, Eleni; Haida, Catherine; Zavitsanou, Assimina; Magiorkinis, Gkikas; Lazanas, Marios C.; Chini, Maria C.; Magafas, N.; Tsogas, Nickolaos; Paparizos, Vassilios A.; Kourkounti, Sofia; Antoniadou, Anastasia C.; Papadopoulos, Antonios I.; Panagopoulos, Periklis; Poulakou, Garyphallia G.; Sakka, V.; Chryssos, Georgios; Drimis, Stylianos; Gargalianos, Panagiotis; Lelekis, Moyssis I.; Chilomenos, G.; Psichogiou, Mina A.; Daikos, George L.; Sabatakou, H.; Panos, George; Haratsis, G.; Kordossis, Theodore; Kontos, Athanasios N.; Koratzanis, Georgios; Theodoridou, Maria C.; Mostrou, Glykeria J.; Spoulou, Vana I.; Schmit, J. C.; Struck, D.; Hemmer, R.; Arendt, V.; Staub, T.; Schneider, F.; Roman, F.; Wensing, A. M.; Boucher, C. A.; van de Vijver, D. A.; van Kessel, A.; van, P. H.; Brinkman, K.; Op de, E. L.; van der Ende, M. E.; Hoepelman, I. M.; van Kasteren, M.; Juttmann, J.; Kuipers, M.; Langebeek, N.; Richter, C.; Santegoets, R. M.; Schrijnders-Gudde, L.; Schuurman, R.; van de Ven, B. J.; Åsjö, Birgitta; Bakken, A. M.; Ormaasen, V.; Aavitsland, P.; Otelea, D.; Paraschiv, S.; Tudor, A. M.; Jevtovic, D.; Salemovic, D.; Stanekova, D.; Habekova, M.; Mokráš, Miloš; Truska, P.; Poljak, M.; Lunar, M.; Babic, Dunja Z.; Tomazic, J.; Vidmar, L.; Vovko, T.; Karner, P.; Clotet, B.; Garcia, F.; Domingo, P.; Galindo, M. J.; Miralles, C.; Del, M. A.; Ribera, E.; Iribarren, J. A.; Ruiz, L.; de la Torre, J.; Vidal, F.; Garcia, F.; Paredes, R. (2015)
      Objectives: The objective of this study was to define the natural genotypic variation of the HIV-1 integrase gene across Europe for epidemiological surveillance of integrase strand-transfer inhibitor (InSTI) resistance. ...
    • Article  

      Processing of the FMRFamide Precursor Protein in the Snail Lymnaea stagnalis: Characterization and Neuronal Localization of a Novel Peptide, ‘SEEPLY’ 

      Santama, Niovi; Wan Li, K.; Bright, K. E.; Yeoman, M. S.; Geraerts, W. P. M.; Benjamin, P. R.; Burke, J. F. (1993)
    • Article  

      Processing of the FMRFamide Precursor Protein in the Snail Lymnaea stagnalis: Characterization and Neuronal Localization of a Novel Peptide, ‘SEEPLY’ 

      Santama, Niovi; Wan Li, K.; Bright, K. E.; Yeoman, M.; Geraerts, W. P. M.; Benjamin, P. R.; Burke, J. F. (1993)
      In the pulmonate snail Lymnaea stagnalis, FMRFamide‐like neuropeptides are encoded by a multi‐exon genomic locus which is subject to regulation at the level of mRNA splicing. We aim to understand the post‐translational ...
    • Article  

      Profiling early infection responses: Pseudomonas aeruginosa eludes host defenses by suppressing antimocrobial peptide gene expression 

      Apidianakis, Yiorgos; Mindrinos, M. N.; Xiao, W.; Lau, G. W.; Baldini, R. L.; Davis, R. W.; Rahme, L. G. (2005)
      Insights into the host factors and mechanisms mediating the primary host responses after pathogen presentation remain limited, due in part to the complexity and genetic intractability of host systems. Here, we employ the ...
    • Book  

      Progress in science and the danger of hubris genetics, transplantation, stem cell research proceedings of the first International Conference on Medical Ethics, Nicosia, 24-26 September 2004 

      Constantinou-Deltas, Constantinos D.; Kalokairinou, Helene M.; Rogge, Sabine (Waxmann, 2006)
    • Article  

      Pseudomonas aeruginosa core metabolism exerts a widespread growth-independent control on virulence 

      Panayidou, Stavria; Georgiades, Kaliopi; Christofi, Theodoulakis; Tamana, Stella; Promponas, Vasilis J.; Apidianakis, Yiorgos (2020)
      To assess the role of core metabolism genes in bacterial virulence - independently of their effect on growth - we correlated the genome, the transcriptome and the pathogenicity in flies and mice of 30 fully sequenced ...
    • Article  

      Pvull polymorphism at the COL1A2 locus 

      Constantinou-Deltas, Constantinos D.; Spotila, L. D.; Zhuang, J.; Sereda, L.; Hanning, C.; Prockop, D. J. (1990)