Browsing Τμήμα Βιολογικών Επιστημών / Department of Biological Sciences by Author "Achilleos, Charis"
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Conference Object
Contextual Bandits for Adapting Treatment in a Mouse Model of de Novo Carcinogenesis
Durand, Audrey; Achilleos, Charis; Iacovides, Demetris; Strati, Katerina; Mitsis, Georgios D.; Pineau, Joelle (2018)In this work, we present a specific case study where we aim to design effective treatment allocation strategies and validate these using a mouse model of skin cancer. Collecting data for modelling ...
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Article
Molecular characterization of HIV type 1 strains from newly diagnosed patients in Cyprus (2007-2009) recovers multiple clades including unique recombinant strains and lack of transmitted drug resistance
Kousiappa, Ioanna; Achilleos, Charis; Hezka, Johana; Lazarou, Yiota; Othonos, Katerina M.; Demetriades, Ioannis; Kostrikis, Leontios G. (2011)HIV-1 evolution generates substantial genetic diversity among isolates, the majority of which are represented in areas where multiple strains cocirculate. A heterogeneous genetic HIV-1 pool has been found in Cyprus, directing ...
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Article
NAA40 contributes to colorectal cancer growth by controlling PRMT5 expression
Demetriadou, Christina; Pavlou, Demetria; Mpekris, Fotios; Achilleos, Charis; Stylianopoulos, Triantafyllos; Zaravinos, Apostolos; Papageorgis, Panagiotis; Kirmizis, Antonis (2019)N-alpha-acetyltransferase 40 (NAA40) catalyzes the transfer of an acetyl moiety to the alpha-amino group of serine 1 (S1) on histones H4 and H2A. Our previous studies linked NAA40 and its corresponding N-terminal acetylation ...
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Article
Shared mechanisms in stemness and carcinogenesis: Lessons from oncogenic viruses
Iacovides, D.; Michael, S.; Achilleos, Charis; Strati, Katerina (2013)A rise in technologies for epigenetic reprogramming of cells to pluripotency, highlights the potential of understanding and manipulating cellular plasticity in unprecedented ways. Increasing evidence points to shared ...
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Article
Terc is dispensable for most of the short-term HPV16 oncogene-mediated phenotypes in mice
Achilleos, Charis; Michael, Stella; Strati, Katerina (2018)High-risk human papillomaviruses (HPVs) have been shown in vitro to impinge on telomere homeostasis in a number of ways. However, the in vivo interaction of viruses with the telomere homeostasis apparatus has not been ...