Browsing Τμήμα Βιολογικών Επιστημών / Department of Biological Sciences by Author "Bartley, S. M."
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Article
Identification of the polycomb group protein SU(Z)12 as a potential molecular target for human cancer therapy
Kirmizis, Antonis; Bartley, S. M.; Farnham, P. J. (2003)We have previously identified SU(Z)12 as an E2F target gene. Because many E2F target genes encode proteins that are critical for the control of cell proliferation, we have further characterized the regulation and expression ...
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Article
Silencing of human polycomb target genes is associated with methylation of histone H3 Lys 27
Kirmizis, Antonis; Bartley, S. M.; Kuzmichev, A.; Margueron, R.; Reinberg, D.; Green, R.; Farnham, P. J. (2004)Polycomb group (PcG) complexes 2 and 3 are involved in transcriptional silencing. These complexes contain a histone lysine methyltransferase (HKMT) activity that targets different lysine residues on histones H1 or H3 in ...
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Article
Use of chromatin immunoprecipitation to study transcriptional deregulation in cancer cells
Farnham, P.; Graveel, C.; Kirmizis, Antonis; Bartley, S. M.; Kel, A.; Kel-Margoulis, O.; Wingender, E.; Zhang, M.; Jatkoe, T.; Madore, S. (2001)