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A serum-free and defined medium for the culture of mammalian postimplantation embryos
(2015)
Whole embryo culture (WEC) of postimplantation rodent embryos is widely used for the study of mammalian embryogenesis and developmental toxicity testing. Its major advantage is that it allows direct access to embryos for ...
New Insights for Ets2 Function in Trophoblast using Lentivirus-Mediated Gene Knockdown in Trophoblast Stem Cells
(2010)
Mouse trophoblast stem (TS) cells represent a unique in vitro system that provides an unlimited supply of TS cells for the study of trophoblast differentiation and TS cell self-renewal. Although the mouse transcription ...
Decidual spiral artery remodeling during early post-implantation period in mice: Investigation of associations with decidual uNK cells and invasive trophoblast
(2012)
Circumferential remodeling of spiral arteries (SAs) during pregnancy is crucial for regulating maternal blood flow into the placenta and clinically important. However its mechanism is still ill defined in humans and mice. ...
Novel spatiotemporal glycome changes in the murine placenta during placentation based on BS-I lectin binding patterns
(2013)
Although spatiotemporal changes of the glycome (full set of glycans, otherwise known as saccharides or carbohydrates) during placenta formation (placentation) are functionally and clinically important, they are poorly ...
Coexpression of H2-Mb and H2-Ab genes during fetal and postnatal development
(1996)
The major histocompatibility complex (MHC) class II-like molecules, H2-M, have an essential role in processing and presentation of antigens by the MHC class II molecules, because functional inactivation of these genes lead ...
New phenotypic aspects of the decidual spiral artery wall during early post-implantation mouse pregnancy
(2011)
During pregnancy the walls of decidual spiral arteries (SAs) undergo clinically important structural modifications crucial for embryo survival/growth and maternal health. However, the mechanisms of SA remodeling (SAR) are ...
Parental origin effects in human trisomy for chromosome 14q: Implications for genomic imprinting
(1998)
Parental origin specific congenital anomalies have been noted in patients with uniparental disomy of the long arm of human chromosome 14 (UPD14). This suggests the presence of imprinted genes, consistent with observations ...
vavCre transgenic mice: A tool for mutagenesis in hematopoietic and endothelial lineages
(2002)
Cre transgenic mice can be used to delete gene sequences flanked by loxP sites in specific somatic tissues. We have generated vavCre transgenic mice, which can be used to inactivate genes specifically in adult hematopoietic ...
Differential expression of the rat retinoid X receptor γ gene during skeletal muscle differentiation suggests a role in myogenesis
(1997)
Even though previous studies have shown that transcripts encoding the murine retinoid X receptor γ (RXRγ) are present in skeletal muscle of mouse embryos and that cultured myoblasts are induced to differentiate upon retinoid ...
Comparative developmental anatomy of the murine and human definitive placentae
(2002)
The placenta of eutherian mammals is a remarkable biological structure. It is composed of both zygote-derived and maternal cells, and mediates the complex interactions between the mother and the fetus that are necessary ...