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dc.contributor.authorValotassiou, Varvaraen
dc.contributor.authorWozniak, Gretaen
dc.contributor.authorSifakis, N.en
dc.contributor.authorDemakopoulos, Nikolaosen
dc.contributor.authorGeorgoulias, Panagiotisen
dc.creatorValotassiou, Varvaraen
dc.creatorWozniak, Gretaen
dc.creatorSifakis, N.en
dc.creatorDemakopoulos, Nikolaosen
dc.creatorGeorgoulias, Panagiotisen
dc.date.accessioned2018-06-22T09:53:22Z
dc.date.available2018-06-22T09:53:22Z
dc.date.issued2008
dc.identifier.urihttps://gnosis.library.ucy.ac.cy/handle/7/41803
dc.description.abstractThe development of functional brain nuclear medicine techniques and their application in the investigation of neuropsychiatric disorders, have contributed significantly in the illumination of the underlying pathophysiological processes of these disorders. Furthermore, Single Photon Emission Computed Tomography (SPECT) and Positron Emission Tomography (PET) brain studies provide information in early diagnosis, differential diagnosis, development of new drugs, and monitoring the response to therapeutic management. SPECT and PET brain imaging require the use of radiopharmaceuticals that cross the intact Blood Brain Barrier (BBB). Such radiotracers have been used in regional Cerebral Blood Flow (rCBF) SPECT and PET imaging and brain metabolism imaging with PET; these are well established methods in the diagnosis and management of various cerebral vascular diseases (e.g. stroke, dementia, epilepsy). Advances in radiotracer chemistry have resulted in the development of molecular imaging which represents the molecular and cellular processes of neurochychiatric diseases. SPECT and PET molecular imaging has become available for the study of acetylcholinergic, dopaminergic and serotonergic systems, as well as for benzodiazepine and opioid receptors, with promising results. More studies are needed to validate the role of molecular imaging in the clinical practice of neuropsychiatric disorders. © 2008 Bentham Science Publishers Ltd.en
dc.language.isoengen
dc.sourceCurrent Clinical Pharmacologyen
dc.subjectHumanen
dc.subjectHumansen
dc.subjectPriority journalen
dc.subjectReviewen
dc.subjectDopamine transporteren
dc.subjectNeurologic diseaseen
dc.subjectTreatment responseen
dc.subjectDepressionen
dc.subjectFluorodeoxyglucose f 18en
dc.subjectPositron emission tomographyen
dc.subjectDifferential diagnosisen
dc.subjectEarly diagnosisen
dc.subjectAnimalsen
dc.subjectAnimalen
dc.subjectMolecular imagingen
dc.subjectSingle photon emission computer tomographyen
dc.subjectSpecten
dc.subjectEmission-computeden
dc.subjectSingle-photonen
dc.subjectTomographyen
dc.subjectBrain perfusionen
dc.subjectCysteine ethyl ester tc 99men
dc.subjectEpilepsyen
dc.subjectNervous system diseasesen
dc.subjectNeuroimagingen
dc.subjectMental diseaseen
dc.subjectRadiopharmaceutical agenten
dc.subjectRadiopharmaceuticalsen
dc.subject6 fluorodopa f 18en
dc.subjectAlzheimer diseaseen
dc.subjectBenzodiazepine receptoren
dc.subjectBlood brain barrieren
dc.subjectBlood-brain barrieren
dc.subjectBrainen
dc.subjectBrain blood flowen
dc.subjectBrain metabolismen
dc.subjectCerebrovascular diseaseen
dc.subjectCholinergic systemen
dc.subjectCitalopramen
dc.subjectDiagnostic agenten
dc.subjectDisordersen
dc.subjectDopamine 2 receptoren
dc.subjectDopaminergic systemen
dc.subjectFlumazenil c 11en
dc.subjectHexamethylpropylene amine oxime technetium tc 99men
dc.subjectLevodopaen
dc.subjectMental disordersen
dc.subjectNeurofibrillary tangleen
dc.subjectNeuroleptic agenten
dc.subjectNeurologicalen
dc.subjectOpiate receptoren
dc.subjectParkinson diseaseen
dc.subjectPeten
dc.subjectPositron-emission tomographyen
dc.subjectPramipexoleen
dc.subjectPsychiatricen
dc.subjectRaclopride c 11en
dc.subjectReceptor bindingen
dc.subjectSchizophreniaen
dc.subjectScintiscanningen
dc.subjectSelegilineen
dc.subjectSenile plaqueen
dc.subjectSerotonin 1a receptoren
dc.subjectSerotoninergic systemen
dc.titleRadiopharmaceuticals in neurological and psychiatric disordersen
dc.typeinfo:eu-repo/semantics/article
dc.identifier.doi10.2174/157488408784293679
dc.description.volume3
dc.description.issue2
dc.description.startingpage99
dc.description.endingpage107
dc.author.facultyΙατρική Σχολή / Medical School
dc.type.uhtypeArticleen


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