Is androgen substitution necessary in hypogonadal patients when they are treated with chemotherapy for malignant diseases?
Ch, F. Tolis
SourceMedical and pediatric oncology
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A patient with hypogonadotropic hypogonadism owing to endogenous gonadotropin releasing hormone deficiency, who developed Hodgkin's disease is described. Chemotherapy administration caused prolonged and life‐threatening myelosuppression; androgen substitution seemed to reverse bone marrow function and to maintain normal peripheral blood counts. Whether or not androgens are a necessary substitution in hypogonadal patients suffering from cancer and undergoing chemotherapy is discussed. Copyright © 1989 Wiley‐Liss, Inc., A Wiley Company