• Article  

      Reply to Ciccolini et al.: Using mathematical modeling to predict response to antiangiogenic therapy in cancer patients 

      Duda, D. G.; Heist, R. S.; Sahani, D. V.; Stylianopoulos, T.; Engelman, J. A.; Jain, R. K. (2015)
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      Representing anisotropy of two-point second-order turbulence velocity correlations using structure tensors 

      Bhattacharya, A.; Kassinos, Stavros C.; Moser, R. D. (2008)
      A locally homogeneous representation for the two-point, second-order turbulent velocity fluctuation Rij(x,r) = 〈u′i(x)u′i(x+r)〉 is formulated in terms of three linearly independent structure tensors [Kassinos et al., J. ...
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      Residual Doping Effects on the Amplitude of Polarization-Induced Electric fields in GaN/AlGaN Quantum Wells 

      Simon, J.; Langer, R.; Barski, A.; Zervos, Matthew; Pelekanos, N. T. (2001)
      We show that residual doping and carrier distribution effects decrease the observed polarization-induced electric fields in GaN/AlGaN quantum wells and that these effects ought to be considered if we want to compare in a ...
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      Residual stresses in solid tumors: Implications to tumor growth and drug delivery 

      Stylianopoulos, T.; Martin, J. D.; Chauhan, V. P.; Munn, L. L.; Jain, R. K. (Affiliation: Edwin L. Steele Laboratory, Department of Radiation Oncology, Harvard Medical School and Massachusetts General Hospital, Boston, MA 02114, United StatesAffiliation: Department of Mechanical and Manufacturing Engineering, University of Cyprus, Nicosia, CyprusCorrespondence Address: Edwin L. Steele Laboratory, Department of Radiation Oncology, Harvard Medical School and Massachusetts General Hospital, Boston, MA 02114, United States, 2012)
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      Resistive switching phenomena in Li xCoO 2 thin films 

      Moradpour, A.; Schneegans, O.; Franger, S.; Revcolevschi, A.; Salot, R.; Auban-Senzier, P.; Pasquier, C.; Svoukis, E.; Giapintzakis, John; Dragos, O.; Ciomaga, V.-C.; Chrétien, P. (2011)
      A substantial resistive switching of Li xCoO 2 mixed-conductor thin films is observed for the first time. The occurrence of possible bipolar switching in these oxide thin films is by current-voltage curves, investigated ...
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      A review of proper modeling techniques 

      Ersal, T.; Fathy, H. K.; Louca, Loucas S.; Rideout, D. G.; Stein, J. L. (Affiliation: University of Michigan, Department of Mechanical Engineering, Ann Arbor, MI, United StatesAffiliation: University of Cyprus, Department of Mechanical and Manufacturing Engineering, Nicosia, CyprusAffiliation: Memorial University of Newfoundland, Department of Engineering and Applied Science, St. John's, NL, CanadaCorrespondence Address: Ersal, T.University of Michigan, Department of Mechanical Engineering, Ann Arbor, MI, United Statesemail: tersal@umich.edu, 2008)
      A dynamic system model is proper for a particular application if it achieves the accuracy required by the application with minimal complexity. Because model complexity often - but not always - correlates inversely with ...
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      A review of proper modeling techniques 

      Ersal, T.; Fathy, H. K.; Rideout, D. G.; Louca, Loucas S.; Stein, J. L. (2008)
      A dynamic system model is proper for a particular application if it achieves the accuracy required by the application with minimal complexity. Because model complexity often-but not always-correlates inversely with simulation ...
    • Conference Object  

      Rheological effects of strusture breakdown in semisolid slurries 

      Alexandrou, Andreas N.; Florides, G. C.; Georgiou, G. C.; Apelian, D. (Affiliation: Department of Mechanical and Industrial Engineering, University Cyprus, P.O.Box 20537, 1678 Nicosia, CyprusAffiliation: Department of Mathematics and Statistics, University of Cyprus, P.O.Box 20537, 1678 Nicosia, CyprusAffiliation: Metal Processing Institute, WPI, Worcester, MA, United StatesCorrespondence Address: Alexandrou, A.N.Department of Mechanical and Industrial Engineering, University Cyprus, P.O.Box 20537, 1678 Nicosia, Cyprus, 2004)
      An essential element for the integration of the semisolid metal (SSM) process in the production of complex commercial components is the availability of accurate mathematical and computational tools that could describe both ...
    • Conference Object  

      Rheology of semisolid suspensions 

      Alexandrou, Andreas N.; Burgos, G. R.; Entov, V. M. (Affiliation: Semisolid Processing Laboratory, Metal Processing Institute, WPI, Worcester, MA 01609, United StatesAffiliation: Polytech. University of Puerto Rico, Mechanical Engineering Department, San Juan 00918, Puerto RicoAffiliation: Institute for Problems in Mechanics, Russian Academy of Science, pr. Vemadskogo, 101, 117526 Moscow, Russian FederationCorrespondence Address: Alexandrou, A.N.Semisolid Processing Laboratory, Metal Processing Institute, WPI, Worcester, MA 01609, United States, 2000)
      The effective use of the semisolid process presumes a good theoretical framework to describe it. The understanding of semisolid behavior should be based upon a combination of basic and empirical knowledge in versatile ...
    • Article  

      Robotic rehabilitation of people with multiple sclerosis with the use of a haptic nine-hole pegboard test 

      Xydas, E. G.; Louca, Loucas S. (2012)
      Multiple Sclerosis (MS) is a complex neurological disease that destroys the myelin sheath of the nerves, consequently affecting the motor control ability in numerous ways. It has been shown that people with MS have the ...
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      Role of constitutive behavior and tumor-host mechanical interactions in the state of stress and growth of solid tumors 

      Voutouri, C.; Mpekris, F.; Papageorgis, P.; Odysseos, A. D.; Stylianopoulos, T. (2014)
      Mechanical forces play a crucial role in tumor patho-physiology. Compression of cancer cells inhibits their proliferation rate, induces apoptosis and enhances their invasive and metastatic potential. Additionally, compression ...
    • Article  

      Role of K/Bi disorder in the electronic structure of β -K2 Bi8 Se13 

      Hoang, K.; Tomic, A.; Mahanti, S. D.; Kyratsi, Theodora; Chung, D. Y.; Tessmer, S. H.; Kanatzidis, M. G. (2009)
      We have carried out tunneling spectroscopy and first-principles studies for β -K2 Bi8 Se13, a promising thermoelectric material with partially disordered mixed K/Bi sites. The tunneling data, obtained with a scanning ...
    • Article  

      The role of mechanical forces in tumor growth and therapy 

      Jain, R. K.; Martin, J. D.; Stylianopoulos, T. (2014)
      Tumors generate physical forces during growth and progression. These physical forces are able to compress blood and lymphatic vessels, reducing perfusion rates and creating hypoxia. When exerted directly on cancer cells, ...
    • Article  

      Role of TGFβ in regulation of the tumor microenvironment and drug delivery (review) 

      Papageorgis, P.; Stylianopoulos, T. (2015)
      Deregulation of cell signaling homeostasis is a predominant feature of cancer initiation and progression. Transforming growth factor β (TGFβ) is a pleiotropic cytokine, which regulates numerous biological processes of ...
    • Article  

      Role of thermal and mechanical effects on drug release from thermosensitive nanocarriers 

      Novell, Anthony; Escoffre, Jean-Michel; Al-Sabbagh, Chantal; Mannaris, Christophoros; Fattal, E.; Tsapis, Nicolas; AVERKIOU, MICHALAKIS A.; Bouakaz, Ayache (2012)
    • Article  

      Role of vascular normalization in benefit from metronomic chemotherapy 

      Mpekris, F.; Baish, J. W.; Stylianopoulos, T.; Jain, R. K. (2017)
      Metronomic dosing of chemotherapy - defined as frequent administration at lower doses - has been shown to be more efficacious than maximum tolerated dose treatment in preclinical studies, and is currently being tested in ...
    • Article  

      Room temperature synthesis and high temperature frictional study of silver vanadate nanorods 

      Singh, D. P.; Polychronopoulou, K.; Rebholz, Claus; Aouadi, S. M. (2010)
      We report the room temperature (RT) synthesis of silver vanadate nanorods (consisting of mainly β-AgVO3) by a simple wet chemical route and their frictional study at high temperatures (HT). The sudden mixing of ammonium ...
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      Scaling rules for diffusive drug delivery in tumor and normal tissues 

      Baish, J. W.; Stylianopoulos, T.; Lanning, R. M.; Kamoun, W. S.; Fukumura, D.; Munn, L. L.; Jain, R. K. (2011)
      Delivery of blood-borne molecules and nanoparticles from the vasculature to cells in the tissue differs dramatically between tumor and normal tissues due to differences in their vascular architectures. Here we show that ...
    • Article  

      Scanning tunneling microscopy of defect states in the semiconductor (formula presented) 

      Urazhdin, S.; Bilc, D. I.; Tessmer, S. H.; Mahanti, S. D.; Kyratsi, Theodora; Kanatzidis, M. G. (2002)
      Scanning tunneling spectroscopy images of (formula presented) doped with excess Bi reveal electronic defect states with a striking shape resembling clover leaves. With a simple tight-binding model, we show that the geometry ...