Τμήμα Μηχανικών Μηχανολογίας και Κατασκευαστικής / Department of Mechanical and Manufacturing Engineering: Recent submissions
Now showing items 281-300 of 1036
-
Conference Object
Fully turbulent flow in a physiologically realistic human airway bifurcation
(TSFP-9, 2015)Recent computational studies have shown that the airflow in the upper human airways is turbulent during much of the respiratory cycle. A feature of respiratory airflow that poses a challenge to computations based on ...
-
Article
The contribution of active and inactive structures to the statistics of a turbulent pipe flow
(2017)The current study is a short follow-up to our most recent work (Stylianou et al., 2016), where among other things we have presented an effective criterion suitable for distinguishing large-scale coherent structures with ...
-
Article
Synthesis, structure, magnetic properties and aqueous solution characterization of p-hydroquinone and phenol iminodiacetate copper(ii) complexes
(2008)The reaction of Cu2+ acetate monohydrate with 2-[N,N′-bis(carboxymethyl)aminomethyl]-4-carboxyphenol (H 4cacp), 2-[N,N-bis(carboxymethyl)aminomethyl]hydroquinone (H 4cah) and the dinucleating 2,5-bis[N,N-bis(carboxymethy ...
-
Article
Direct numerical simulation of particle laden flow in a human airway bifurcation model
(2016)During the delivery of inhaled medicines, and depending on the size distribution of the particles in the formulation, airway bifurcations are areas of preferential deposition. Previous studies of laminar flow through airway ...
-
Article
Aerial Oxidation of a VIV-Iminopyridine Hydroquinonate Complex: A Trap for the VIV-Semiquinonate Radical Intermediate
(2015)The reaction of 2,5-bis[N,N′-bis(2-pyridyl-aminomethyl)aminomethyl]-p-hydroquinone (H2bpymah) with VO2+ salts in acetonitrile or water at a low pH (2.2-3.5) results in the isolation of [VIV(O)(Cl)2(μ-bpymah)], the ...
-
Article
Structural and thermal characterization of La5Ca 9Cu24O41 thin films grown by pulsed laser deposition on (1 1 0) SrTiO3 substrates
(2012)In the present study stoichiometric, b-axis oriented La5Ca 9Cu24O41 thin films were grown by pulsed laser deposition on (1 1 0) SrTiO3 substrates in the temperature range 600-750 °C. High resolution transmission electron ...
-
Article
A general framework for computing the turbulence structure tensors
(2015)Good measures of the turbulence structure are important for turbulence modeling, flow diagnostics and analysis. Structure information is complementary to the componentality anisotropy that the Reynolds stress tensor carries, ...
-
Conference Object
Permeability calculations in three-dimensional fiber networks with varying degrees of orientation
(Affiliation: Radiation Oncology, Harvard Medical School, Massachusetts General Hospital, Boston, MA 02129, United StatesAffiliation: Chemical Engineering and Materials Science, University of Minnesota, 151 Amundson Hall, Minneapolis, MN 55455-0132, United StatesAffiliation: Scientific Computation Research Center, Rensselaer Polytechnic Institute, Troy, NY 12180, United StatesCorrespondence Address: Stylianopoulos, T.Radiation Oncology, Harvard Medical School, Massachusetts General Hospital, Boston, MA 02129, United States, 2008)
-
Conference Object
Permeability calculations in three-dimensional fiber networks
(Affiliation: Department of Chemical Engineering, University of Minnesota, United StatesAffiliation: Scientific Computation Research Center (SCOREC), RPIAffiliation: Department of Biomedical Engineering, University of Minnesota, United StatesCorrespondence Address: Stylianopoulos, T.Department of Chemical Engineering, University of MinnesotaUnited States, 2009)
-
Article
Atomic Force Microscopy Probing of Cancer Cells and Tumor Microenvironment Components
(2016)Cancer cells have different characteristics from normal cells in terms of morphology, cell–cell interactions, cytoskeleton organization, cell growth rates, and cell-extracellular matrix interactions. Although the clarification ...
-
Article
Permeability calculations in three-dimensional isotropic and oriented fiber networks
(2008)Hydraulic permeabilities of fiber networks are of interest for many applications and have been studied extensively. There is little work, however, on permeability calculations in three-dimensional random networks. Computational ...
-
Conference Object
The effect of flow rate, head position, and inhaler orientation on the airflow and particle deposition in an mri-based mouth-throat geometry
(International Symposium on Turbulence and Shear Flow Phenomena, TSFP10, 2017)The mouth-throat plays a key role in the administration of inhaled medicines. It is an area of intense filtration, where an unacceptably high fraction of the released drug dose is deposited and thus wasted. Due to the ...
-
Article
Transforming growth factor-β modulates pancreatic cancer associated fibroblasts cell shape, stiffness and invasion
(2018)Background: Tumor microenvironment consists of the extracellular matrix (ECM), stromal cells, such as fibroblasts (FBs) and cancer associated fibroblasts (CAFs), and a myriad of soluble factors. In many tumor types, including ...
-
Article
Exploring the nano-surface of collagenous and other fibrotic tissues with AFM
(2017)Atomic force microscope (AFM) is a powerful and invaluable tool for imaging and probing the mechanical properties of biological samples at the nanometric scale. The importance of nano-scale characterization and nanomechanics ...
-
Article
Particle-laden flow in a physiologically realistic human airway bifurcation
(2018)Predicting regional deposition patterns of inhaled aerosols is important for the design and optimization of pharmaceutical formulations. © 2018, Springer International Publishing AG.
-
Article
Diffusion of particles in the extracellular matrix: The effect of repulsive electrostatic interactions
(2010)Diffusive transport of macromolecules and nanoparticles in charged fibrous media is of interest in many biological applications, including drug delivery and separation processes. Experimental findings have shown that ...
-
Article
Coevolution of solid stress and interstitial fluid pressure in tumors during progression: Implications for vascular collapse
(2013)The stress harbored by the solid phase of tumors is known as solid stress. Solid stress can be either applied externally by the surrounding normal tissue or induced by the tumor itself due to its growth. Fluid pressure is ...
-
Article
Causes, consequences, and remedies for growth-induced solid stress in murine and human tumors
(2012)The presence of growth-induced solid stresses in tumors has been suspected for some time, but these stresses were largely estimated using mathematical models. Solid stresses can deform the surrounding tissues and compress ...
-
Article
Cationic nanoparticles have superior transvascular flux into solid tumors: Insights from a mathematical model
(2013)Despite their great promise, only a few nanoparticle formulations have been approved for clinical use in oncology. The failure of nano-scale drugs to enhance cancer therapy is in large part due to inefficient delivery. To ...
-
Article
Multistage nanoparticles for improved delivery into tumor tissue
(2012)The enhanced permeability and retention (EPR) effect has been a key rationale for the development of nanoscale carriers to solid tumors. As a consequence of EPR, nanotherapeutics are expected to improve drug and detection ...