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dc.contributor.authorChristoforou, Irene C.en
dc.contributor.authorKoutentis, Panayiotis Andreasen
dc.contributor.authorMichaelidou, Sophia S.en
dc.creatorChristoforou, Irene C.en
dc.creatorKoutentis, Panayiotis Andreasen
dc.creatorMichaelidou, Sophia S.en
dc.date.accessioned2019-11-21T06:17:20Z
dc.date.available2019-11-21T06:17:20Z
dc.date.issued2006
dc.identifier.issn1424-6376
dc.identifier.urihttp://gnosis.library.ucy.ac.cy/handle/7/55327
dc.description.abstractThe chemistry of various 5H-1,2,3-dithiazoles is investigated with emphasis on assisted ring opening and ring closure reactions leading to new heterocycles. Thus on treatment with catalytic tetraalkylammonium iodide N-(2-chloropyrid-3-yl)- and N-(4-chloropyrid-3-yl)-4-chloro-1,2,3-dithiazol-5H- imines 19 and 20 give thiazolo[5,4-b]pyridine-2-carbonitrile 16 and thiazolo-[4,5-c]pyridine-2-carbonitrile 17 respectively. Similar treatment of bisdithiazoles 29 and 30 afford high yielding routes to 1,3,4-thiadiazole-2,5- dicarbonitrile 31 and thiazole-2,4,5-tricarbonitrile 32 respectively. N-(Pyrid-3-yl)-4-chloro-1,2,3-dithiazol-5H-imine 36 reacts with secondary alkylamines to give as main product pyrido[2,3-d]pyrimidines 37 and several minor byproducts including a deep green quinoidal 2,2′-bithiazole 40. Dithiazolylidenacetonitriles 43 react with either anhydrous HBr or tetraalkylammonium chloride to afford a series of 3-halo-4-substituted- isothiazole-5-carbonitriles 45 and 52 respectively. The reactions of dithiazoles 43 with tetraalkylammonium chloride are complicated owing to the formation of isothiazolo-pentathiepin-8-carbonitrile 53, isothiazolodithiin-4,5,7- tricarbonitrile 54, tetracyanothiophene 56 and an unidentified compound 55 whose possible structures are proposed. The mechanistic rationales for the formation of the identified products are proposed.en
dc.sourceArkivocen
dc.source.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-31544442173&partnerID=40&md5=34c6e2c56442329bd73f90b9f87dec3c
dc.subjectAcetyleneen
dc.subjectDithiazoleen
dc.subjectHeterocycleen
dc.subjectIsothiazoleen
dc.subjectThiazoleen
dc.title1,2,3-Dithiazole chemistry in heterocyclic synthesisen
dc.typeinfo:eu-repo/semantics/article
dc.description.volume2006
dc.description.issue7
dc.description.startingpage207
dc.description.endingpage223
dc.author.faculty002 Σχολή Θετικών και Εφαρμοσμένων Επιστημών / Faculty of Pure and Applied Sciences
dc.author.departmentΤμήμα Χημείας / Department of Chemistry
dc.type.uhtypeArticleen
dc.description.notes<p>Cited By :19</p>en
dc.source.abbreviationArkivocen
dc.contributor.orcidKoutentis, Panayiotis Andreas [0000-0002-4652-7567]
dc.contributor.orcidChristoforou, Irene C. [0000-0001-6624-3548]


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