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dc.contributor.authorGeorgiou, Christiana A.en
dc.contributor.authorConstantinou, Michalis S.en
dc.contributor.authorKapnissi‐Christodoulou, Constantina P.en
dc.creatorGeorgiou, Christiana A.en
dc.creatorConstantinou, Michalis S.en
dc.creatorKapnissi‐Christodoulou, Constantina P.en
dc.date.accessioned2019-11-21T06:19:08Z
dc.date.available2019-11-21T06:19:08Z
dc.date.issued2014
dc.identifier.urihttp://gnosis.library.ucy.ac.cy/handle/7/55501
dc.description.abstractIn recent years, cholesterol oxidation products (COPs) have drawn scientific interest, particularly due to their implications on human health. A big number of these compounds have been demonstrated to be cytotoxic, mutagenic, and carcinogenic. The main source of COPs is through diet, and particularly from the consumption of cholesterol-rich foods. This raises questions about the safety of consumers, and it suggests the necessity for the development of a sensitive and a reliable analytical method in order to identify and quantify these components in food samples. Sample preparation is a necessary step in the analysis of COPs in order to eliminate interferences and increase sensitivity. Numerous publications have, over the years, reported the use of different methods for the extraction and purification of COPs. However, no method has, so far, been established as a routine method for the analysis of COPs in foods. Therefore, it was considered important to overview different sample preparation procedures and evaluate the different preparative parameters, such as time of saponification, the type of organic solvents for fat extraction, the stationary phase in solid phase extraction, etc., according to recovery, precision and simplicity. © 2013 Elsevier Ltd. All rights reserved.en
dc.sourceFood Chemistryen
dc.source.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-84884504477&doi=10.1016%2fj.foodchem.2013.08.123&partnerID=40&md5=1db406af7e2f05a0b185123ab50a7d8b
dc.subjectreviewen
dc.subjectunclassified drugen
dc.subjectCholesterolen
dc.subjecttriacylglycerolen
dc.subjecthigh performance liquid chromatographyen
dc.subjectreliabilityen
dc.subjectsolvent extractionen
dc.subjectroom temperatureen
dc.subjectOxidation-Reductionen
dc.subjectOxidationen
dc.subjectPhase separationen
dc.subjectdegradationen
dc.subjectEpoxy Compoundsen
dc.subjectAnalytical methoden
dc.subjectCholesterol oxidation productsen
dc.subjectdieten
dc.subjectmethanolen
dc.subjectHydrolysisen
dc.subjectphospholipiden
dc.subjectdissolutionen
dc.subjecthigh temperatureen
dc.subjectExtractionen
dc.subjectLipid extractionen
dc.subjectSample preparationen
dc.subjectSaponificationen
dc.subjectSolid phase extractionen
dc.subjectSolid-phase extractionen
dc.subjectacylglycerolen
dc.subjectAnalytic Sample Preparation Methodsen
dc.subjectchloroformen
dc.subjectCholestanesen
dc.subjectcholesterol esteren
dc.subjectcholesterol oxidation producten
dc.subjectCholesterol, Dietaryen
dc.subjectConsumer Product Safetyen
dc.subjectemulsionen
dc.subjectExtraction and purificationsen
dc.subjectfat intakeen
dc.subjectfatty aciden
dc.subjectFood Analysisen
dc.subjectFood Contaminationen
dc.subjectFood safetyen
dc.subjectgas chromatographyen
dc.subjecthexaneen
dc.subjectHydroxycholesterolsen
dc.subjectKetocholesterolsen
dc.subjectlipid analysisen
dc.subjectliquid liquid extractionen
dc.subjectLiquid-Liquid Extractionen
dc.subjectmilken
dc.subjectpropanolen
dc.subjectpurificationen
dc.subjectSample preparation procedureen
dc.subjectStationary phaseen
dc.subjectvitaminen
dc.titleSample preparation: A critical step in the analysis of cholesterol oxidation productsen
dc.typeinfo:eu-repo/semantics/article
dc.identifier.doi10.1016/j.foodchem.2013.08.123
dc.description.volume145
dc.description.startingpage918
dc.description.endingpage926
dc.author.faculty002 Σχολή Θετικών και Εφαρμοσμένων Επιστημών / Faculty of Pure and Applied Sciences
dc.author.departmentΤμήμα Χημείας / Department of Chemistry
dc.type.uhtypeArticleen
dc.description.notes<p>Cited By :11</p>en
dc.source.abbreviationFood Chem.en
dc.contributor.orcidKapnissi‐Christodoulou, Constantina P. [0000-0003-3755-1052]
dc.gnosis.orcid0000-0003-3755-1052


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