dc.contributor.author | Koutentis, Panayiotis Andreas | en |
dc.contributor.author | Loizou, G. | en |
dc.contributor.author | Lo Re, D. | en |
dc.creator | Koutentis, Panayiotis Andreas | en |
dc.creator | Loizou, G. | en |
dc.creator | Lo Re, D. | en |
dc.date.accessioned | 2019-11-21T06:20:33Z | |
dc.date.available | 2019-11-21T06:20:33Z | |
dc.date.issued | 2011 | |
dc.identifier.uri | http://gnosis.library.ucy.ac.cy/handle/7/55727 | |
dc.description.abstract | Silver(I) fluoride (AgF)-mediated intramolecular nonoxidative and oxidative palladium-catalyzed cyclizations of 1,3-diphenyl- and 8-iodo-1,3- diphenylbenzo[e][1,2,4]triazin-7(1H)-ones 6a (R = H) and 7a (R = I) afford a new 'alkaloid like' ring system 2-phenyl-6H-[1,2,4]triazino[5,6,1-jk]carbazol-6-one 8a (triazafluoranthenone) in 86 and 100% yields, respectively. Furthermore, these cyclization protocols were used to prepare triazafluoranthenone analogues 8b - e bearing dialkylamino, methoxy, and phenylsulfanyl substituents at C-5, which were also independently synthesized from triazafluoranthenone 8a by regioselective nucleophilic addition. Similar AgF-mediated intramolecular nonoxidative and oxidative palladium-catalyzed cyclizations of 8,10-dihydro-1-iodo-10-phenylphenazin-2(7H)-ones 13 gave the new 'alkaloid like' ring system 8H-indolo[1,2,3-mn]phenazin-8-one 14 in 80 and 18% yields, respectively. © 2011 American Chemical Society. | en |
dc.source | Journal of Organic Chemistry | en |
dc.source.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-79960204366&doi=10.1021%2fjo200966k&partnerID=40&md5=406c1416ea2db06915bc300eb4d2577b | |
dc.subject | article | en |
dc.subject | unclassified drug | en |
dc.subject | synthesis | en |
dc.subject | Oxidation-Reduction | en |
dc.subject | Catalysis | en |
dc.subject | cross linking | en |
dc.subject | palladium | en |
dc.subject | Molecular Structure | en |
dc.subject | Organometallic Compounds | en |
dc.subject | oxidation reduction potential | en |
dc.subject | drug structure | en |
dc.subject | Stereoisomerism | en |
dc.subject | Nitrogen compounds | en |
dc.subject | nucleophilicity | en |
dc.subject | Addition reactions | en |
dc.subject | silver | en |
dc.subject | Fluorides | en |
dc.subject | Silver Compounds | en |
dc.subject | Cyclization | en |
dc.subject | Regioselective nucleophilic addition | en |
dc.subject | Ring systems | en |
dc.subject | 2 phenyl 5 (phenylthio) 6h[1,2,4]triazino[ 5,6,1 jk]carbazol 6 one | en |
dc.subject | 2 phenyl 5 (pyrrolidin 1 yl) 6h[1,2,4]triazino[ 5,6,1 jk]carbazol 6 one | en |
dc.subject | 5 (diethylamino) 2 phenyl 6h[1,2,4]triazino[ 5,6,1 jk]carbazol 6 one | en |
dc.subject | 5 methoxy 2 phenyl 6h[1,2,4]triazino[5,6,1 jk]carbazol 6 one | en |
dc.subject | 8,10 dihydro 1 iodo 10 phenylphenazin 2(7h)one | en |
dc.subject | Aza Compounds | en |
dc.subject | Cyclizations | en |
dc.subject | fluoranthene | en |
dc.subject | Metabolites | en |
dc.subject | Methoxy | en |
dc.subject | Non-oxidative | en |
dc.subject | Silver halides | en |
dc.title | Synthesis of triazafluoranthenones via silver(I)-mediated nonoxidative and oxidative intramolecular palladium-catalyzed cyclizations | en |
dc.type | info:eu-repo/semantics/article | |
dc.identifier.doi | 10.1021/jo200966k | |
dc.description.volume | 76 | |
dc.description.issue | 14 | |
dc.description.startingpage | 5793 | |
dc.description.endingpage | 5802 | |
dc.author.faculty | 002 Σχολή Θετικών και Εφαρμοσμένων Επιστημών / Faculty of Pure and Applied Sciences | |
dc.author.department | Τμήμα Χημείας / Department of Chemistry | |
dc.type.uhtype | Article | en |
dc.description.notes | <p>Cited By :16</p> | en |
dc.source.abbreviation | J.Org.Chem. | en |
dc.contributor.orcid | Koutentis, Panayiotis Andreas [0000-0002-4652-7567] | |
dc.gnosis.orcid | 0000-0002-4652-7567 | |