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Investigating the role of Methyl CpG Binding proteins in Cervical Cancer
DNA methylation (5mC) is one of the main epigenetic modifications that drive gene regulation. Methyl CpG binding proteins (MBDs) bind methylated DNA and recruit the nucleosome remodelling and deacetylase complex (Nurd) ...
The HPV16 E6 and E7 oncogenes modify Glutamine metabolism in Cervical Cancers
Metabolic reprogramming is an established hallmark of cancer. Malignant cells induce metabolic adjustments to meet their high energy demands and sustain rapid proliferation. These metabolic changes involve modifications ...