• Article  

      The 1.76 Å resolution crystal structure of glycogen phosphorylase b complexed with glucose, and CP320626, a potential antidiabetic drug 

      Oikonomakos, Nikos G.; Zographos, Spyros E.; Skamnaki, Vicky T.; Archontis, Georgios Z. (2002)
      CP320626, a potential antidiabetic drug, inhibits glycogen phosphorylase in synergism with glucose. To elucidate the structural basis of synergistic inhibition, we determined the structure of muscle glycogen phosphorylase ...
    • Article  

      Algorithmic mechanisms for reliable crowdsourcing computation under collusion 

      Fernández Anta, Antonio; Georgiou, Chryssis; Mosteiro, Miguel A.; Pareja, D. (2015)
      We consider a computing system where a master processor assigns a task for execution to worker processors that may collude. We model the workers' decision of whether to comply (compute the task) or not (return a bogus ...
    • Article  

      Autosomal-dominant medullary cystic kidney disease type 1: Clinical and molecular findings in six large Cypriot families 

      Stavrou, Christoforos V.; Koptides, Michael; Tombazos, C.; Psara, E.; Patsias, Charalambos; Zouvani, Ioanna; Kyriacou, Kyriacos C.; Hildebrandt, F.; Christofides, Tasos C.; Pierides, Alkis M.; Constantinou-Deltas, Constantinos D. (2002)
      Background. Autosomal-dominant medullary cystic kidney disease (ADMCKD), a hereditary chronic interstitial nephropathy, recently attracted attention because of the cloning or mapping of certain gene loci, namely NPHP1, ...
    • Article  

      Autosomal-dominant medullary cystic kidney disease type 1: Clinical and molecular findings in six large Cypriot familiesAAA 

      Stavrou, Christoforos V.; Koptides, Michael; Tombazos, C.; Psara, E.; Patsias, Charalambos; Zouvani, Ioanna; Kyriacou, Kyriacos C.; Hildebrandt, F.; Christofides, Tasos C.; Pierides, Alkis M.; Constantinou-Deltas, Constantinos D. (2002)
      Background. Autosomal-dominant medullary cystic kidney disease (ADMCKD), a hereditary chronic interstitial nephropathy, recently attracted attention because of the cloning or mapping of certain gene loci, namely NPHP1, ...
    • Article  

      Binding free energies and free energy components from molecular dynamics and Poisson-Boltzmann calculations. Application to amino acid recognition by aspartyl-tRNA synthetase 

      Archontis, Georgios Z.; Simonson, T.; Karplus, M. (2001)
      Specific amino acid binding by aminoacyl-tRNA synthetases (aaRS) is necessary for correct translation of the genetic code. Engineering a modified specificity into aminoacyl-tRNA synthetases has been proposed as a means to ...
    • Article  

      Can we use area per surfactant as a quantitative test model of specific ion effects? 

      Zemb, Th; Belloni, L.; Dubois, M.; Aroti, Andria; Leontidis, Epameinondas (2004)
      The three main currently proposed approaches for understanding specific ion effects are briefly described. In some experimentally well defined and simplified situations, one can decouple ion specificity effects from all ...
    • Article  

      Cationic amphiphilic model networks based on symmetrical ABCBA pentablock terpolymers: Synthesis, characterization, and modelling 

      Triftaridou, Aggeliki I.; Vamvakaki, Maria; Patrickios, Costas S. (2007)
      Eight isomeric networks based on equimolar terpolymers were synthesized using group transfer polymerization (GTP) and were characterized in terms of their swelling properties. Two hydrophilic monomers, the nonionic methoxy ...
    • Article  

      Cationic double-hydrophilic model networks: Synthesis, characterization, modeling and protein adsorption studies 

      Loizou, Elena; Triftaridou, Aggeliki I.; Georgiou, Theoni K.; Vamvakaki, Maria; Patrickios, Costas S. (2003)
      Group transfer polymerization (GTP) was used for the preparation of eight networks based on two hydrophilic monomers, 2-(dimethylamino)ethyl methacrylate (DMAEMA) and poly(ethylene glycol) methacrylate (PEGMA). Ethylene ...
    • Article  

      Comparison of three-jet events in pp̄ collisions at √s = 1.8 TeV to predictions from a next-to-leading order QCD calculation 

      Acosta, D.; Affolder, T.; Albrow, M. G.; Ambrose, D.; Amidei, D.; Anikeev, K.; Antos, J.; Apollinari, G.; Arisawa, T.; Artikov, A.; Ashmanskas, W.; Azfar, F.; Azzi-Bacchetta, P.; Bacchetta, N.; Bachacou, H.; Badgett, W.; Barbaro-Galtieri, A.; Barnes, V. E.; Barnett, B. A.; Baroiant, S.; Barone, M.; Bauer, G.; Bedeschi, F.; Behari, S.; Belforte, S.; Bell, W. H.; Bellettini, G.; Bellinger, J.; Benjamin, D.; Beretvas, Andrew; Bhatti, A.; Binkley, M.; Bisello, D.; Bishai, M.; Blair, R. E.; Blocker, C.; Bloom, K.; Blumenfeld, B.; Bocci, A.; Bodek, A.; Bolla, G.; Bolshov, A.; Bortoletto, D.; Boudreau, J.; Bromberg, C.; Brubaker, E.; Budagov, J.; Budd, H. S.; Burkett, K.; Busetto, G.; Byrum, K. L.; Cabrera, S.; Campbell, M.; Carithers, W.; Carlsmith, D.; Castro, A.; Cauz, D.; Cerri, A.; Cerrito, L.; Chapman, J.; Chen, C.; Chen, Y. C.; Chertok, M.; Chiarelli, G.; Chlachidze, G.; Chlebana, F.; Chu, M. L.; Chung, J. Y.; Chung, W. H.; Chung, Y. S.; Ciobanu, C. I.; Clark, A. G.; Coca, M.; Connolly, A.; Convery, M.; Conway, J.; Cordelli, M.; Cranshaw, J.; Culbertson, R.; Dagenhart, D.; D'Auria, S.; De Barbaro, P.; De Cecco, S.; Dell'Agnello, Simone; Dell'Orso, M.; Demers, S.; Demortier, L.; Deninno, M.; De Pedis, D.; Derwent, P. F.; Dionisi, Carlo; Dittmann, J. R.; Dominguez, A.; Donati, S.; D'Onofrio, M.; Dorigo, T.; Eddy, N.; Erbacher, R.; Errede, D.; Errede, S.; Eusebi, R.; Farrington, S.; Feild, R. G.; Fernandez, J. P.; Ferretti, C.; Field, R. D.; Fiori, I.; Flaugher, B.; Flores-Castillo, L. R.; Foster, G. W.; Franklin, M.; Friedman, J.; Furic, I.; Gallinaro, M.; Garfinkel, A. F.; Gay, C.; Gerdes, D. W.; Gerstein, E.; Giagu, S.; Giannetti, P.; Giolo, K.; Giordani, M.; Giromini, P.; Glagolev, V.; Glenzinski, D.; Gold, M.; Goldschmidt, N.; Goldstein, J.; Gomez, G.; Goncharov, M.; Gorelov, I.; Goshaw, A. T.; Gotra, Y.; Goulianos, Konstantin; Gresele, A.; Grosso-Pilcher, C.; Guenther, M.; Guimaraes Da Costa, J.; Haber, C.; Hahn, S. R.; Halkiadakis, Eva; Handler, R.; Happacher, F.; Hara, K.; Harris, R. M.; Hartmann, F.; Hatakeyama, K.; Hauser, J.; Heinrich, J.; Hennecke, M.; Herndon, M.; Hill, C.; Hocker, A.; Hoffman, K. D.; Hou, S.; Huffman, B. T.; Hughes, R.; Huston, J.; Incandela, J.; Introzzi, G.; Iori, M.; Issever, C.; Ivanov, A.; Iwata, Y.; Iyutin, B.; James, E.; Jones, M.; Kamon, T.; Kang, J.; Unel, M.; Kartal, S.; Kasha, H.; Kato, Y.; Kennedy, R. D.; Kephart, R.; Kilminster, B.; Kim, D. H.; Kim, H. S.; Kim, M. J.; Kim, S. B.; Kim, S. H.; Kim, T. H.; Kim, Y. K.; Kirby, M.; Kirsch, L.; Klimenko, S.; Koehn, P.; Kondo, K.; Konigsberg, J.; Korn, A.; Korytov, A.; Kroll, J.; Kruse, M.; Krutelyov, V.; Kuhlmann, S. E.; Kuznetsova, N.; Laasanen, A. T.; Lami, S.; Lammel, S.; Lancaster, J.; Lancaster, M.; Lander, R.; Lannon, K.; Lath, A.; Latino, G.; LeCompte, T.; Le, Y.; Lee, J.; Lee, S. W.; Leonardo, N.; Leone, S.; Lewis, J. D.; Li, K.; Lin, C. S.; Lindgren, M.; Liss, T. M.; Litvintsev, D. O.; Liu, T.; Lockyer, N. S.; Loginov, A.; Loreti, M.; Lucchesi, D.; Lukens, P.; Lyons, L.; Lys, J.; Madrak, R.; Maeshima, K.; Maksimovic, P.; Malferrari, L.; Manca, G.; Mangano, M.; Mariotti, M.; Martin, A.; Martin, M.; Martin, V.; Martínez, M.; Mazzanti, P.; McFarland, K. S.; McIntyre, P.; Menguzzato, M.; Menzione, A.; Merkel, P.; Mesropian, C.; Meyer, A.; Miao, T.; Miller, J. S.; Miller, R.; Miscetti, S.; Mitselmakher, G.; Moggi, N.; Moore, R.; Moulik, T.; Mukherjee, A.; Mulhearn, M.; Muller, T.; Munar, A.; Murat, P.; Nachtman, J.; Nahn, S.; Nakano, I.; Napora, R.; Nelson, C.; Nelson, T.; Neu, C.; Neubauer, M. S.; Newman-Holmes, C.; Niell, F.; Nigmanov, T.; Nodulman, L.; Oh, S. H.; Oh, Y. D.; Ohsugi, T.; Okusawa, T.; Orejudos, W.; Pagliarone, C.; Palmonari, F.; Paoletti, R.; Papadimitriou, Vaia; Patrick, J.; Pauletta, G.; Paulini, M.; Pauly, T.; Paus, C.; Pellett, D.; Penzo, A.; Phillips, T. J.; Piacentino, G.; Piedra, J.; Pitts, K. T.; Pompoš, A.; Pondrom, L.; Pope, G.; Poukhov, O.; Pratt, T.; Prokoshin, F.; Proudfoot, J.; Ptohos, Fotios; Punzi, G.; Rademacker, J.; Rakitine, A.; Ratnikov, F.; Ray, H.; Reichold, A.; Renton, P.; Rescigno, M.; Rimondi, F.; Ristori, L.; Robertson, W. J.; Rodrigo, T.; Rolli, S.; Rosenson, L.; Roser, R.; Rossin, R.; Rott, C.; Roy, A.; Ruiz, A.; Ryan, D.; Safonov, A.; St. Denis, R.; Sakumoto, W. K.; Saltzberg, D.; Sanchez, C.; Sansoni, A.; Santi, L.; Sarkar, S.; Savard, P.; Savoy-Navarro, A.; Schlabach, P.; Schmidt, E. E.; Schmidt, M. P.; Schmitt, M.; Scodellaro, L.; Scribano, A.; Sedov, A.; Seidel, S.; Seiya, Y.; Semenov, A.; Semeria, F.; Shapiro, M. D.; Shepard, P. F.; Shibayama, T.; Shimojima, M.; Shochet, M.; Sidoti, A.; Sill, A.; Sinervo, P.; Slaughter, A. J.; Sliwa, K.; Snider, F. D.; Snihur, R.; Spezziga, M.; Spiegel, L.; Spinella, F.; Spiropulu, Maria; Stefanini, A.; Strologas, John; Stuart, D.; Sukhanov, A.; Sumorok, K.; Suzuki, T.; Takashima, R.; Takikawa, K.; Tanaka, M.; Tecchio, M.; Teng, P. K.; Terashi, K.; Tesarek, R. J.; Tether, S.; Thorn, J.; Thomas, T. L.; Thompson, A. S.; Thomson, E.; Tipton, P.; Tkaczyk, S.; Toback, D.; Tollefson, K.; Tonelli, D.; Tönnesmann, M.; Toyoda, H.; Trischuk, W.; Tseng, J.; Tsybychev, D.; Turini, N.; Ukegawa, F.; Unverhau, T.; Vaiciulis, T.; Varganov, A.; Vataga, E.; Vejcik III, S.; Velev, G.; Veramendi, G.; Vidal, R.; Vila, I.; Vilar, R.; Volobouev, I.; Von Der Mey, M.; Wagner, R. G.; Wagner, R. L.; Wagner, W.; Wan, Z.; Wang, C.; Wang, M. J.; Wang, S. M.; Ward, B.; Waschke, S.; Waters, D.; Watts, T.; Weber, M.; Wester III, W. C.; Whitehouse, B.; Wicklund, A. B.; Wicklund, E.; Williams, H. H.; Wilson, P.; Winer, B. L.; Wolbers, S.; Wolter, M.; Worm, S.; Wu, X.; Würthwein, F.; Yang, U. K.; Yao, W.; Yeh, G. P.; Yi, K.; Yoh, J.; Yoshida, T.; Yu, I.; Yu, S.; Yun, J. C.; Zanello, L.; Zanetti, A.; Zetti, F.; Zucchelli, S. (2005)
      The properties of three-jet events with total transverse energy greater than 320 GeV and individual jet energy greater than 20 GeV have been analyzed and compared to absolute predictions from a next-to-leading order (NLO) ...
    • Article  

      A correction to the calculation of the Gibbs free energy of adsorption for biomolecules in ion-exchange systems 

      Patrickios, Costas S.; Yamasaki, E. N. (1997)
      We wish to propose a correction to the methodology introduced by Gerstner et al. [J.A. Gerstner, J.A. Bell, S.M. Cramer, Biophys. Chem. 52 (1994) 97-106] for the calculation of Gibbs free energies of adsorption of biomolecules ...
    • Article  

      Critical mass of Wilson fermions: A comparison of perturbative and Monte Carlo results 

      Follana, E.; Panagopoulos, Haralambos G. (2001)
      We calculate the critical value of the hopping parameter, κc , in lattice QCD with Wilson fermions, to two loops in perturbation theory. This quantity is an additive renormalization
    • Article  

      Crystal/glass phase change in KSb5S8 studied through thermal analysis techniques 

      Chrissafis, K.; Kyratsi, Theodora; Paraskevopoulos, K. M.; Kanatzidis, M. G. (2004)
      The reversible crystal-glass and glass-crystal transitions discovered in KSb5S8 were studied in detail with nonisothermal scanning calorimetry techniques. When cooled, molten KSb5S8 becomes a metastable glass, which can ...
    • Article  

      Crystallographic and computational studies on 4-phenyl-N-(β-D- glucopyranosyl)-1H-1,2, 3-triazole-1-acetamide, an inhibitor of glycogen phosphorylase: Comparison with α-D-glucose, N-acetyl-β-D- glucopyranosylamine and N-benzoyl-N′-β-D-glucopyranosyl urea binding 

      Alexacou, Kyra Melinda; Hayes, Joseph M.; Tiraidis, Costas; Zographos, Spyros E.; Leonidas, Demetres D.; Chrysina, Evangelia D.; Archontis, Georgios Z.; Oikonomakos, Nikos G.; Paul, J. V.; Varghese, B.; Loganathan, D. (2008)
      4-Phenyl-N-(β-D-glucopyranosyl)-1H-1,2,3-triazole-1-acetamide (glucosyltriazolylacetamide) has been studied in kinetic and crystallographic experiments with glycogen phosphorylase b (GPb), in an effort to utilize its ...
    • Article  

      Determination of thorium, uranium and potassium elemental concentrations in surface soils in Cyprus 

      Tzortzis, M.; Tsertos, Haralambos (2004)
      A comprehensive study was conducted to determine thorium, uranium and potassium elemental concentrations in surface soils throughout the accessible area of Cyprus using high-resolution γ-ray spectrometry. A total of 115 ...
    • Article  

      Determining neutralization serotypes of HIV type 1 by neural networks 

      Kostrikis, Leontios G.; Michalopoulou, Z. -H; Cao, Yun Zhen; Moore, J. P.; Ho, David D. (1996)
    • Article  

      A DFT study of the ground state multiplicities of linear vs angular polyheteroacenes 

      Constantinides, Christos P.; Koutentis, Panayiotis Andreas; Schatz, J. (2004)
      Unrestricted density functional calculations in combination with the broken-symmetry approach and spin-projection methods have been employed to study a series of formally 4n π antiaromatic linear and angular polyheteroacenes. ...
    • Article  

      Discrete and encapsulated molecular grids: Homometallic Mn15 and heterometallic Mn24Ni2 aggregates 

      Charalambous, Maria; Zartilas, Sotiris M.; Moushi, Eleni E.; Papatriantafyllopoulou, Constantina; Manos, Manolis J.; Stamatatos, Theocharis C.; Mukherjee, S.; Nastopoulos, Vassilios; Christou, George; Tasiopoulos, Anastasios J. (2014)
      Two molecular grid-like clusters are reported, one is a discrete [3 × 5] grid and the other a [3 × 4] grid within a Mn12Ni 2 loop. Both Mn24Ni2 and Mn15 aggregates display novel and aesthetically pleasing structures with ...
    • Article  

      Electron affinities of a homologous series of tertiary alkyl radicals and their C-H bond dissociation energies (BDEs) 

      Petrou, Panayiotis S.; Nicolaides, Athanassios V. (2009)
      Heats of formation have been derived from G3(MP2)//B3LYP and G3MP2B3(+) atomization energies for tert-butyl radical (6R), cubyl radical, bicyclooctyl radical (1R), and tricyclo[3.3.n.03,7]alk-3(7)-yl (n=0-3, 2R-5R) radicals, ...
    • Article  

      The elusive benzocyclobutenylidene: A combined computational and experimental attempt 

      Nicolaïdes, Andrew N.; Matsushita, Takashi; Yonezawa, K.; Sawai, S.; Tomioka, H.; Stracener, L. L.; Hodges, J. A.; McMahon, R. J. (2001)
      Ab initio and density functional theory calculations predict that benzocyclobutenylidene (1) has a singlet ground state in contrast to the parent phenylcarbene and many other simply substituted arylcarbenes. Calculations ...
    • Article  

      Fronts in a piecewise linear Schrödinger equation 

      Theodorakis, Stavros (2002)
      We examine the conditions that are necessary for the appearance of fronts as solutions of nonlinear Schrödinger-like equations. We show that fronts can appear even when the potential in these equations has only one minimum. ...