Browsing Τμήμα Βιολογικών Επιστημών / Department of Biological Sciences by Title

Now showing items 477-496 of 677

    • Article  

      Particle tracking microrheology of purified gastrointestinal mucins 

      Georgiades, Pantelis; Pudney, Paul D. A.; Thornton, David J.; Waigh, Thomas A.; Blacklow, Stephen (2014)
    • Article  

      Pathogenesis of intestinal Pseudomonas aeruginosa infection in patients with cancer 

      Markou, P.; Apidianakis, Yiorgos (2014)
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      The pathogenic properties of a novel and conserved gene product, KerV, in proteobacteria 

      An, D.; Apidianakis, Yiorgos; Boechat, A. L.; Baldini, R. L.; Goumnerov, B. C.; Rahme, L. G. (2009)
      Identification of novel virulence factors is essential for understanding bacterial pathogenesis and designing antibacterial strategies. In this study, we uncover such a factor, termed KerV, in Proteobacteria. Experiments ...
    • Article  

      Pathways and genes differentially expressed in the motor cortex of patients with sporadic amyotrophic lateral sclerosis 

      Lederer, C. W.; Torrisi, A.; Pantelidou, M.; Santama, Niovi; Cavallaro, S. (2007)
    • Article  

      Patterns of species richness on very small islands: The plants of the Aegean archipelago 

      Panitsa, M.; Tzanoudakis, D.; Triantis, Kostas A.; Sfenthourakis, Spyros (2006)
      Aim: To investigate the species-area relationship (SAR) of plants on very small islands, to examine the effect of other factors on species richness, and to check for a possible Small Island Effect (SIE). Location: The study ...
    • Article  

      Patterns of taxonomic diversity among terrestrial isopods 

      Sfenthourakis, Spyros; Taiti, S. (2015)
      The publication of the world catalog of terrestrial isopods some ten years ago by Schmalfuss has facilitated research on isopod diversity patterns at a global scale. Furthermore, even though we still lack a comprehensive ...
    • Article  

      Patterns of transmitted HIV drug resistance in Europe vary by risk group 

      Frentz, D.; Van De Vijver, D.; Abecasis, A. B.; Albert, Jan; Hamouda, O.; Jørgensen, L.; Kücherer, C.; Struck, D.; Schmit, J. -C; Vercauteren, J.; Åsjö, Birgitta; Balotta, Claudia; Bergin, C.; Beshkov, Danail; Camacho, Ricardo J.; Clotet, B.; Griskevicius, A.; Grossman, Z.; Horban, A.; Kolupajeva, T.; Korn, K.; Kostrikis, Leontios G.; Linka, K. L. M.; Nielsen, C.; Otelea, D.; Paraskevis, Dimitrios N.; Paredes, R.; Poljak, M.; Puchhammer-Stöckl, E.; Sönnerborg, A.; Stanekova, D.; Stanojevic, M.; Vandamme, A. -M; Boucher, C.; Wensing, A. (2014)
      Background: In Europe, a continuous programme (SPREAD) has been in place for ten years to study transmission of drug resistant HIV. We analysed time trends of transmitted drug resistance mutations (TDRM) in relation to the ...
    • Article  

      Persistence of episomal HIV-1 infection intermediates in patients on highly active anti-retroviral therapy 

      Sharkey, M. E.; Teo, I.; Greenough, T.; Sharova, N.; Luzuriaga, K.; Sullivan, J. L.; Bucy, R. P.; Kostrikis, Leontios G.; Haase, A.; Veryard, C.; Davaro, R. E.; Cheeseman, S. H.; Daly, J. S.; Bova, C.; Ellison III, R. T.; Mady, B.; Lai, K. K.; Moyle, G.; Nelson, M.; Gazzard, B.; Shaunak, S.; Stevenson, M. (2000)
      Treatment of HIV-1-infected individuals with a combination of anti- retroviral agents results in sustained suppression of HIV-1 replication, as evidenced by a reduction in plasma viral RNA to levels below the limit of ...
    • Article  

      Persistent HIV-1 infection of natural killer cells in patients receiving highly active antiretroviral therapy 

      Valentin, A.; Rosati, M.; Patenaude, D. J.; Hatzakis, Angelos E.; Kostrikis, Leontios G.; Lazanas, Marios C.; Wyvill, K. M.; Yarchoan, R.; Pavlakis, G. N. (2002)
      We have identified a subset of CD56+CD3- human natural killer (NK) cells that express CD4 and the HIV coreceptors CCR5 and CXCR4. These cells can be productively infected in vitro by both CCR5- and CXCR4-using molecular ...
    • Article  

      PESI - A taxonomic backbone for Europe 

      Güntsch, A.; de Jong, Y.; Kouwenberg, J.; Boumans, L.; Hussey, C.; Hyam, R.; Nicolson, N.; Kirk, P.; Paton, A.; Michel, E.; Guiry, M. D.; Boegh, P. S.; Pedersen, H.; Enghoff, H.; von Raab-Straube, E.; Geoffroy, M.; Müller, A.; Kohlbecker, A.; Berendsohn, W.; Appeltans, W.; Arvanitidis, C.; Vanhoorne, B.; Declerck, J.; Vandepitte, L.; Hernandez, F.; Nash, R.; Costello, M. J.; Ouvrard, D.; Bezard-Falgas, P.; Bourgoin, T.; Wetzel, F. T.; Glöckler, F.; Korb, G.; Ring, C.; Hagedorn, G.; Häuser, C.; Aktaç, N.; Asan, A.; Ardelean, A.; Borges, P. A. V.; Dhora, D.; Khachatryan, H.; Malicky, M.; Ibrahimov, S.; Tuzikov, A.; De Wever, A.; Moncheva, S.; Spassov, N.; Chobot, K.; Popov, A.; Boršic, I.; Sfenthourakis, Spyros; Kõljalg, U.; Uotila, P.; Olivier, G.; Dauvin, J. -C; Tarkhnishvili, D.; Chaladze, G.; Tuerkay, M.; Legakis, A.; Peregovits, L.; Gudmundsson, G.; ólafsson, E.; Lysaght, L.; Galil, B. S.; Raimondo, F. M.; Domina, G.; Stoch, F.; Minelli, A.; Spungis, V.; Budrys, E.; Olenin, S.; Turpel, A.; Walisch, T.; Krpach, V.; Gambin, M. T.; Ungureanu, L.; Karaman, G.; Kleukers, R. M. J. C.; Stur, E.; Aagaard, K.; Valland, N.; Moen, T. L.; Bogdanowicz, W.; Tykarski, P.; Weslawski, J. M.; Kedra, M.; Martins, A. M. F.; Abreu, A. D.; Silva, R.; Medvedev, S.; Ryss, A.; Šimic, S.; Marhold, K.; Stloukal, E.; Tome, D.; Ramos, M. A.; Valdés, B.; Pina, F.; Kullander, S.; Telenius, A.; Gonseth, Y.; Tschudin, P.; Sergeyeva, O.; Vladymyrov, V.; Rizun, V. B.; Raper, C.; Lear, D.; Stoev, P.; Penev, L.; Rubio, A. C.; Backeljau, T.; Saarenmaa, H.; Ulenberg, S. (2015)
      Reliable taxonomy underpins communication in all of biology, not least nature conservation and sustainable use of ecosystem resources. The flexibility of taxonomic interpretations, however, presents a serious challenge for ...
    • Article  

      Pharmaceutical biology: Preface 

      Constantinou, Andreas I.; Singletary, K. W. (2002)
    • Article  

      Phenotypic heterogeneity in osteogenesis imperfecta: The mildly affected mother of a proband with a lethal variant has the same mutation substituting cysteine for α1-glycine 904 in a type I procollagen gene (COL1A1) 

      Constantinou-Deltas, Constantinos D.; Pack, M. A.; Young, S. B.; Prockop, D. J. (1990)
      A proband with a lethal variant of osteogenesis imperfecta (OI) has been shown to have, in one allele in a gene for type I procollagen (COL1A1), a single base mutation that converted the codon for α1-glycine 904 to a codon ...
    • Article  

      Phenoxodiol (2H-1-benzopyran-7-0,1,3-(4-hydroxyphenyl)), a novel isoflavone derivative, inhibits DNA topoisomerase II by stabilizing the cleavable complex 

      Constantinou, Andreas I.; Husband, A. (2002)
      Cancer therapeutic drugs that inhibit DNA topoisomerase (topo) II by stabilizing the cleavable complex are collectively known as topo II poisons. Phenoxodiol is a synthetic derivative of the plant isoflavone daidzein and ...
    • Article  

      Phenoxodiol, a novel isoflavone derivative, inhibits dimethylbenz[a]anthracene (DMBA)-induced mammary carcinogenesis in female Sprague-Dawley rats 

      Constantinou, Andreas I.; Mehta, R.; Husband, A. (2003)
      The present study was undertaken to evaluate the potential cancer chemopreventive effects of novel synthetic derivatives of isoflavones. Initially these agents were tested in a mouse mammary organ culture (MMOC) model. ...
    • Article  

      Phenoxodiol, an anticancer isoflavene, induces immunomodulatory effects in vitro and in vivo 

      Georgaki, Sylvianna; Skopeliti, Margarita; Tsiatas, Marinos L.; Nicolaou, Katerina A.; Ioannou, Kyriaki; Husband, A.; Bamias, Aristotelis T.; Dimopoulos, Meletios A.; Constantinou, Andreas I.; Tsitsilonis, Ourania E. (2009)
      Phenoxodiol (PXD) is a synthetic analogue of the plant isoflavone genistein with improved anticancer efficacy. Various properties and mechanisms of action have been attributed to the drug, the most important being its ...
    • Article  

      The phosphoform of the regulatory subunit RII of cyclic AMP-dependent protein kinase possesses intrinsic topoisomerase activity 

      Constantinou, Andreas I.; Squinto, S. P.; Jungmann, R. A. (1985)
      The phosphoform of the type II regulatory subunit (phospho-RII-cAMP) of cAMP-dependent protein kinase from rat liver was found to possess intrinsic topoisomerase activity towards several DNA substrates such as φX174, pBR322, ...
    • Article  

      Phytoplankton Phenology in the Coastal Zone of Cyprus, Based on Remote Sensing and In Situ Observations 

      Sfenthourakis, Spyros; Demetriou, Monica; Raitsos, Dionysios E.; Kournopoulou, Antonia; Mandalakis, Manolis; Psarra, Stella (MDPI, 2021-12-21)
      Alterations in phytoplankton biomass, community structure and timing of their growth (phenology), are directly implicated in the carbon cycle and energy transfer to higher trophic levels of the marine food web. Due to the ...
    • Article  

      PKD2, a gene for polycystic kidney disease that encodes an integral membrane protein 

      Mochizuki, Toshio; Wu, G.; Hayashi, Tomohito; Xenophontos, Stavroulla L.; Veldhuisen, B.; Saris, J. J.; Reynolds, D. M.; Cai, Y.; Gabow, P. A.; Pierides, Alkis M.; Kimberling, W. J.; Breuning, M. H.; Constantinou-Deltas, Constantinos D.; Peters, D. J. M.; Somlo, Stefan (1996)
      A second gene for autosomal dominant polycystic kidney disease was identified by positional cloning. Nonsense mutations in this gene (PKD2) segregated with the disease in three PKD2 families. The predicted 968-amino acid ...
    • Article  

      Point-counterpoint: Soy intake for breast cancer patients 

      Block, K. I.; Constantinou, Andreas I.; Hilakivi-Clarke, L.; Hughes, C.; Tripathy, D.; Tice, J. A. (2002)
    • Article  

      Polarized distribution of Bcr-Abl in migrating myeloid cells and co-localization of Bcr-Abl and its target proteins 

      Skourides, Paris A.; Perera, S. A.; Ren, R. (1999)
      Bcr-Abl plays a critical role in the pathogenesis of Philadelphia chromosome-positive leukemia. Although a large number of substrates and interacting proteins of Bcr-Abl have been identified, it remains unclear whether ...