Browsing Τμήμα Βιολογικών Επιστημών / Department of Biological Sciences by Title
Now showing items 426-445 of 677
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Article
N-alpha-terminal Acetylation of Histone H4 Regulates Arginine Methylation and Ribosomal DNA Silencing
(2013)Post-translational modifications of histones play a key role in DNA-based processes, like transcription, by modulating chromatin structure. N-terminal acetylation is unique among the numerous histone modifications because ...
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NAA40 contributes to colorectal cancer growth by controlling PRMT5 expression
(2019)N-alpha-acetyltransferase 40 (NAA40) catalyzes the transfer of an acetyl moiety to the alpha-amino group of serine 1 (S1) on histones H4 and H2A. Our previous studies linked NAA40 and its corresponding N-terminal acetylation ...
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Article
Nature and consequences of biological reductionism for the immunological study of infectious diseases
(2017)Evolution has conserved "economic" systems that perform many functions, faster or better, with less. For example, three to five leukocyte types protect from thousands of pathogens. To achieve so much with so little, ...
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Article
Near full-length genetic analysis of HIV sequences derived from Cyprus: Evidence of a highly polyphyletic and evolving infection
(2009)The molecular epidemiology of HIV-1 infection was previously studied in Cyprus but the degree of HIV-1 diversity has remained indefinable. The main objective of the present study is to examine HIV-1 strains isolated from ...
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Article
Near-full genome characterisation of two natural intergenotypic 2k/1b recombinant hepatitis c virus isolates
(2011)Few natural intergenotypic hepatitis C virus (HCV) recombinants have been characterised, and only RF1-2k/1b has demonstrated widespread transmission. The near-full length genome sequences for two cases of 2k/1b recombinants ...
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Near-full genome characterization of unclassified hepatitis c virus strains relating to genotypes 1 and 4
(2011)Near-full genome sequences are presented in this report for the first time of unclassified HCV strains amplified using RT-PCR from plasma of patients living in Cyprus. One strain appears to be a unique genotype-1-like ...
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Book Chapter
Nephrogenetics and Nephrodiagnostics
(John Wiley & Sons, Ltd, 2018)Recent technological developments have revolutionized contemporary molecular diagnostics, while next-generation sequencing (NGS) for DNA analysis has become an integral part of delivery of modern medicine. Nephrogenetics ...
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Article
Nest-site preferences of Eleonora's Falcon (Falco eleonorae) on uninhabited islets of the Aegean Sea using GIS and species distribution models
(2012)Eleonora's Falcon breeds colonially on small islands of the Mediterranean Sea and Macaronesia. Despite the wealth of papers highlighting the importance of nesting characteristics on this species' breeding performance, few ...
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Article
Neural hyperplasia induced by RNA interference with m4/mα gene activity
(2000)The E(spl) complex (E(spl)-C) contains three different classes of genes that are downstream of Notch signaling. The bHLH genes mediate the Notch signal by repressing proneural gene activity, for example during the ...
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Neural modulation of gut motility by myomodulin peptides and acetylcholine in the snail Lymnaea
(1998)
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Neural network controlling feeding in Lymnaea stagnalis: Immunocytochemical localization of myomodulin, small cardioactive peptide, buccalin, and FMRFamide‐ related peptides
(1994)This paper investigates the distribution of four classes of neuropeptides, myomodulin, small cardioactive peptide (SCP), buccalin, and FMRFamide, in central neurons forming the network that underlies feeding behavior in ...
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Article
Neuralized Encodes a Peripheral Membrane Protein Involved in Delta Signaling and Endocytosis
(2001)Activation of the Notch (N) receptor involves an intracellular proteolytic step triggered by shedding of the extracellular N domain (N-EC) upon ligand interaction. The ligand Dl has been proposed to effect this N-EC shedding ...
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Article
Neuropeptide FMRFamide Gene Expression
(1992)This chapter describes a variety of techniques to isolate (starting from the amino acid sequence only) and to analyze FMRFamide (Phe-Met-Arg-Phe- NH2) gene expression.* These include the polymerase chain reaction (PCR), ...
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Article
New amino acid polymorphism, Ala/Val4058, in exon 45 of the polycystic kidney disease 1 gene: Evolution of alleles
(1997)The PKD1 gene, which is responsible for the most common form of autosomal dominant polycystic kidney disease, has recently been cloned and sequenced. Many disease-causing mutations have been characterized in this gene, ...
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A new genus of Trachelipodidae Strouhal, 1953 (Crustacea, Isopoda, Oniscidea) from the eastern Mediterranean
(2015)Levantoniscus n. gen. is erected for two new species from Cyprus: Levantoniscus bicostulatus n. sp. and Levantoniscus makrisi n. sp. Levantoniscus wahrmani (Strouhal, 1968) n. comb. from Israel and southern Turkey is ...
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New Insights for Ets2 Function in Trophoblast using Lentivirus-Mediated Gene Knockdown in Trophoblast Stem Cells
(2010)Mouse trophoblast stem (TS) cells represent a unique in vitro system that provides an unlimited supply of TS cells for the study of trophoblast differentiation and TS cell self-renewal. Although the mouse transcription ...