Τμήμα Βιολογικών Επιστημών / Department of Biological Sciences: Recent submissions

Now showing items 141-160 of 677

    • Article  

      A preliminary RAPD-PCR analysis of Cimicifuga species and other botanicals used for women's health 

      Xu, H.; Fabricant, D. S.; Piersen, C. E.; Bolton, J. L.; Pezzuto, J. M.; Fong, H.; Totura, S.; Farnsworth, N. R.; Constantinou, Andreas I. (2002)
      Traditional taxonomic methods of botanical identification that rely primarily on morphological observations cannot be used efficiently when only powdered plant materials are available. Thus, our objectives were to determine ...
    • Article  

      Medullary cystic kidney disease type 1: Mutational analysis in 37 genes based on haplotype sharing 

      Wolf, M. T. F.; Mucha, B. E.; Hennies, H. C.; Attanasio, M.; Panther, F.; Zalewski, I.; Karle, S. M.; Otto, E. A.; Constantinou-Deltas, Constantinos D.; Fuchshuber, A.; Hildebrandt, F. (2006)
      Medullary cystic kidney disease type 1 (MCKD1) is an autosomal dominant, tubulo-interstitial nephropathy that causes renal salt wasting and end-stage renal failure in the fourth to seventh decade of life. MCKD1 was localized ...
    • Article  

      A translation frameshift mutation induced by a cytosine insertion in the Polycystic Kidney Disease 2 gene (PKD2) 

      Xenophontos, Stavroulla L.; Constantinides, Rolandos; Hayashi, Tomohito; Mochizuki, Toshio; Somlo, Stefan; Pierides, Alkis M.; Constantinou-Deltas, Constantinos D. (1997)
      Mutations in the PKD2 gene on the long arm of chromosome 4 are responsible for ~ 15% of cases of polycystic kidney disease. Perhaps the only difference from the more common ADPKD1 cases is the rate of progression of cystic ...
    • Article  

      A functional variant in NEPH3 gene confers high risk of renal failure in primary hematuric glomerulopathies. Evidence for predisposition to microalbuminuria in the general population 

      Voskarides, Konstantinos; Stefanou, Charalambos; Pieri, Myrtani; Demosthenous, Panayiota; Felekkis, Kyriacos N.; Arsali, Maria; Athanasiou, Yiannis; Xydakis, D.; Stylianou, Konstantinos G.; Daphnis, Eugenios K.; Goulielmos, George N.; Loizou, P.; Savige, J.; Höhne, M.; Völker, L. A.; Benzing, T.; Maxwell, P. H.; Gale, D. P.; Gorski, M.; Böger, C.; Kollerits, B.; Kronenberg, F.; Paulweber, B.; Zavros, Michalis; Pierides, Alkis M.; Constantinou-Deltas, Constantinos D. (2017)
      Background Recent data emphasize that thin basement membrane nephropathy (TBMN) should not be viewed as a form of benign familial hematuria since chronic renal failure (CRF) and even end-stage renal disease (ESRD), is a ...
    • Article  

      A sequence polymorphism in the 3′-nontranslated region of the proα1 chain of type I procollagen 

      Westerhausen, A. I.; Constantinou-Deltas, Constantinos D.; Prockop, D. J. (1990)
    • Article  

      Variation in breeding parameters of Eleonora's falcon (Falco eleonorae) and factors affecting its reproductive performance 

      Xirouchakis, Stavros M.; Fric, Jakob; Kassara, Christina; Portolou, Danae; Dimalexis, Anastasios; Karris, Georgios; Barboutis, Christos; Latsoudis, Panagiotis; Bourdakis, Stratis; Kakalis, Eleftherios; Sfenthourakis, Spyros (2012)
      We gathered data for a four-year period (2004-2007) on the nesting ecology and reproductive performance of Eleonora's falcon in the Aegean Sea. We investigated in an indirect way the relation between clutch size and ...
    • Article  

      Hepatitis C virus infection epidemiology among people who inject drugs in europe: A systematic review of data for scaling up treatment and prevention 

      Wiessing, L.; Ferri, M.; Grady, B.; Kantzanou, M.; Sperle, I.; Cullen, K. J.; Hatzakis, Angelos E.; Prins, M.; Vickerman, P.; Lazarus, J. V.; Hope, V. D.; Matheï, C.; Busch, M.; Bollaerts, K.; Bogdanova, V.; Nesheva, E.; Fotsiou, N.; Kostrikis, Leontios G.; Mravčík, V.; Řehák, V.; Částková, J.; Hobstová, J.; Nechanská, B.; Fouchard, J.; Abel-Ollo, K.; Tefanova, V.; Tallo, T.; Brummer-Korvenkontio, H.; Brisacier, A. -C; Michot, I.; Jauffret-Roustide, M.; Zimmermann, R.; Fotiou, A.; Gazdag, G.; Tarján, A.; Galvin, B.; Thornton, L.; Cruciani, M.; Basso, M.; Karnite, A.; Caplinskiene, I.; Lopes, S.; Origer, A.; Melillo, J.; Camilleri, M.; Demanuele, C. O.; Croes, E.; Op De Coul, E.; Rosińska, M.; Struzik, M.; Martins, M.; Duran, D.; Vilar, G.; Resende, M. E.; Martins, H. C.; Abagiu, A. O.; Ruta, S.; Arama, V.; Kopilovic, B.; Kustec, T.; Klavs, I.; Aleixandre, N. L.; Folch, C.; Bravo, M. J.; Gómez, R. S.; Berglund, T.; Strandberg, J.; Hotho, D.; Van Houdt, S.; Low, A.; Mcdonald, B.; Platt, L.; Kalamara, E.; Giraudon, I.; Groshkova, T.; Palladino, C.; Hutchinson, S.; Ncube, F.; Eramova, I.; Goldberg, D.; Vicente, J.; Griffiths, P. (2014)
      Background: People who inject drugs (PWID) are a key population affected by hepatitis C virus (HCV). Treatment options are improving and may enhance prevention
    • Article  

      Epistatic Role of the MYH9/APOL1 Region on Familial Hematuria Genes 

      Voskarides, Konstantinos; Demosthenous, Panayiota; Papazachariou, Louiza; Arsali, Maria; Athanasiou, Yiannis; Zavros, Michalis; Stylianou, Konstantinos G.; Xydakis, D.; Daphnis, Eugenios K.; Gale, D. P.; Maxwell, P. H.; Elia, Avraam; Pattaro, C.; Pierides, Alkis M.; Constantinou-Deltas, Constantinos D. (2013)
      Familial hematuria (FH) is explained by at least four different genes (see below). About 50% of patients develop late proteinuria and chronic kidney disease (CKD). We hypothesized that MYH9/APOL1, two closely linked genes ...
    • Article  

      COL4A3/COL4A4 mutations link familial hematuria and focal segmental glomerulosclerosis. Glomerular epithelium destruction via basement membrane thinning? 

      Voskarides, Konstantinos; Pierides, Alkis M.; Constantinou-Deltas, Constantinos D. (2008)
      The recent description of multiple gene defects in hereditary podocytopathies and in hereditary glomerular basement membrane diseases has dramatically improved the current state of our knowledge on the renal glomerular ...
    • Article  

      NPHS2 screening with SURVEYOR in Hellenic children with steroid-resistant nephrotic syndrome 

      Voskarides, Konstantinos; Makariou, Christiana; Papagregoriou, Gregory N.; Stergiou, Nikolaos; Printza, Nikoleta G.; Alexopoulos, Efstathios; Elia, Avraam; Papachristou, Fotios Th; Pierides, Alkis M.; Georgaki, Eleni; Constantinou-Deltas, Constantinos D. (2008)
    • Article  

      COL4A3 founder mutations in Greek-Cypriot families with thin basement membrane nephropathy and focal segmental glomerulosclerosis dating from around 18th century 

      Voskarides, Konstantinos; Patsias, Charalambos; Pierides, Alkis M.; Constantinou-Deltas, Constantinos D. (2008)
      Mutations in the COL4A3/COL4A4 genes of type IV collagen account for about 40% of cases of thin basement membrane nephropathy, a condition that is estimated to affect 1% or more of the general population. We recently ...
    • Article  

      Y-chromosome phylogeographic analysis of the Greek-Cypriot population reveals elements consistent with Neolithic and Bronze Age settlements 

      Voskarides, Konstantinos; Mazières, S.; Hadjipanagi, Despina; Di Cristofaro, J.; Ignatiou, Anastasia; Stefanou, Charalambos; King, R. J.; Underhill, P. A.; Chiaroni, J.; Constantinou-Deltas, Constantinos D. (2016)
      Background: The archeological record indicates that the permanent settlement of Cyprus began with pioneering agriculturalists circa 11,000years before present, (ca. 11,000 y BP). Subsequent colonization events followed, ...
    • Article  

      On 'Incidence of renal failure and nephroprotection by RAAS inhibition in heterozygous carriers of X-chromosomal and autosomal recessive Alport mutations' 

      Voskarides, Konstantinos; Pierides, Alkis M.; Constantinou-Deltas, Constantinos D. (2013)
    • Article  

      Mesoscopic fluorescence tomography for in-vivo imaging of developing Drosophila 

      Vinegoni, C.; Razansky, D.; Pitsouli, Chrysoula; Perrimon, N.; Ntziachristos, V.; Weissleder, R. (2009)
      Visualizing developing organ formation as well as progession and treatment of disease often heavily relies on the ability to optically interrogate molecular and functional changes in intact living organisms. Most existing ...
    • Article  

      COL4A3/COL4A4 mutations producing focal segmental glomerulosclerosis and renal failure in thin basement membrane nephropathy 

      Voskarides, Konstantinos; Damianou, Loukas; Neocleous, Vassos; Zouvani, Ioanna; Christodoulidou, Stalo; Hadjiconstantinou, Valsamakis E.; Ioannou, Kyriakos; Athanasiou, Yiannis; Patsias, Charalambos; Alexopoulos, Efstathios; Pierides, Alkis M.; Kyriacou, Kyriacos C.; Constantinou-Deltas, Constantinos D. (2007)
      Mutations in the COL4A3/COL4A4 genes of type IV collagen have been found in ∼40% of cases of thin basement membrane nephropathy, which is characterized by microscopic hematuria and is classically thought to cause proteinuria ...
    • Article  

      2nd combined working group and management committee meeting of urine and kidney proteomics COST action 29-30 March 2009, Nafplio, Greece 

      Vlahou, Antonia; Allmaier, G.; Attwood, T.; Bongcam-Rudloff, E.; Charonis, Aristidis S.; Frokiaer, J.; Mischak, H.; Schanstra, J.; Spasovski, G.; Aasberg, A.; Allory, Y.; Arthur, J.; Attwood, T.; Banks, R.; Baumann, M.; Benigni, A.; Bezerianos, Anastasios; Campistol, J. M.; Candiano, G.; Capasso, G.; Carpentier, S.; Dadlez, M.; Constantinou-Deltas, Constantinos D.; Dijilianov, D.; De Zeeuw, D.; Decramer, S.; Dihazi, H.; Domon, B.; Endlich, N.; d'Alche-Buc, F.; D'Haese, P.; Edelman, A.; Egido, J.; El Nahas, M.; Farinazzo, A.; Fernandez-Llama, P.; Feldt-Rasmussen, B.; Frokiaer, J.; Gansevoort, R.; Garbis, S.; Garin, J.; Ghiggeri, G. M.; Gimenez, I.; Granier, C.; Goumenos, Dimitrios S.; Haylor, J. L.; Hilario, M.; Holthofer, H.; Kalousis, Alexandros; Kaski, S.; Knepper, M.; Korneti, P.; Kossida, Sophia A.; Langham, R.; Loftheim, H.; Lopez-Novoa, J.; Luider, T.; Magni, F.; Malats, N.; Martin, J. L.; Mayrhofer, C.; Monsarrat, B.; Mueller, G.; Nielsen, S.; Norling, M.; O'Connell, S.; Ortiz, A.; Perunicic-Pekovic, G.; Planelles, G.; Polenakovic, M.; Promponas, Vasilis J.; Rasic-Milutinovic, Z.; Rehulka, P.; Peter, K.; Righetti, P. G.; Ronco, P.; Ryan, M.; Sánchez-Carbayo, M.; Schanstra, J.; Semmes, J.; Sheehan, D.; Stenman, U. -H; Stodkilde-Jorgensen, L.; Tasic, V.; Theodorescu, D.; Thongboonkerd, V.; Toncheva, D.; Tsillibari, E.; Tsiotis, Georgios; Unwin, R.; Vanholder, R.; Vassilev, D.; Vickers, M. E.; Verhulst, A.; Vilasi, Annalisa; Vlahakos, D.; Vonk, R.; Wright, P. C.; Yamamoto, Tadashi; Yutaka, Y.; Zielenkiewicz, P. (2009)
      EuroKUP (Urine and Kidney Proteomics
    • Article  

      Evidence that NPHS2-R229Q predisposes to proteinuria and renal failure in familial hematuria 

      Voskarides, Konstantinos; Arsali, Maria; Athanasiou, Yiannis; Elia, Avraam; Pierides, Alkis M.; Constantinou-Deltas, Constantinos D. (2012)
      Background Familial hematuria (FH) is associated with at least two pathological entities: Thin basement membrane nephropathy (TBMN), caused by heterozygous COL4A3/ COL4A4 mutations, and C3 nephropathy caused by CFHR5 ...
    • Article  

      Screening for mutations in kidney-related genes using SURVEYOR nuclease for cleavage at heteroduplex mismatches 

      Voskarides, Konstantinos; Constantinou-Deltas, Constantinos D. (2009)
      SURVEYOR is a new mismatch-specific plant DNA endonuclease that is very efficient for mutation scanning in heteroduplex DNA. It is much faster, cheaper, more sensitive, and easier to perform than other "traditional" mutation ...
    • Article  

      Mesoscopic fluorescence tomography for in-vivo imaging of developing Drosophila. 

      Vinegoni, C.; Razansky, D.; Pitsouli, Chrysoula; Perrimon, N.; Ntziachristos, V.; Weissleder, R. (2009)
      Visualizing developing organ formation as well as progession and treatment of disease often heavily relies on the ability to optically interrogate molecular and functional changes in intact living organisms. Most existing ...
    • Article  

      In vivo imaging of Drosophila melanogaster pupae with mesoscopic fluorescence tomography 

      Vinegoni, C.; Pitsouli, Chrysoula; Razansky, D.; Perrimon, N.; Ntziachristos, V. (2008)
      We report a technique for fluorescence tomography that operates beyond the penetration limits of tissue-sectioning fluorescence microscopy. The method uses multi-projection illumination and photon transport description in ...