Τμήμα Βιολογικών Επιστημών / Department of Biological Sciences: Recent submissions

Now showing items 161-180 of 677

    • Article  

      A novel family of katanin-like 2 protein isoforms (KATNAL2), interacting with nucleotide-binding proteins Nubp1 and Nubp2, are key regulators of different MT-based processes in mammalian cells 

      Ververis, A.; Christodoulou, A.; Christoforou, Maria; Kamilari, C.; Lederer, C. W.; Santama, Niovi (2016)
    • Article  

      Targeting pattern recognition receptors (PRR) for vaccine adjuvantation: From synthetic PRR agonists to the potential of defective interfering particles of viruses 

      Vasou, A.; Sultanoglu, N.; Goodbourn, S.; Randall, R. E.; Kostrikis, Leontios G. (2017)
      Modern vaccinology has increasingly focused on non-living vaccines, which are more stable than live-attenuated vaccines but often show limited immunogenicity. Immunostimulatory substances, known as adjuvants, are traditionally ...
    • Article  

      Transmission of drug-resistant HIV-1 is stabilizing in Europe 

      Vercauteren, J.; Wensing, A. M. J.; Van De Vijver, D. A. M. C.; Albert, Jan; Balotta, Claudia; Hamouda, O.; Kücherer, C.; Struck, D.; Schmit, J. -C; Åsjö, Birgitta; Bruckova, M.; Camacho, Ricardo J.; Clotet, B.; Coughlan, S.; Grossman, Z.; Horban, A.; Korn, K.; Kostrikis, Leontios G.; Nielsen, C.; Paraskevis, Dimitrios N.; Poljak, M.; Puchhammer-Stöckl, E.; Riva, C.; Ruiz, L.; Salminen, M.; Schuurman, R.; Sonnerborg, A.; Stanekova, D.; Stanojevic, M.; Vandamme, A. M.; Boucher, C. A. B. (2009)
      The SPREAD Programme investigated prospectively the time trend from September 2002 through December 2005 of transmitted drug resistance (TDR) among 2793 patients in 20 European countries and in Israel with newly diagnosed ...
    • Article  

      Vernonia kotschyana roots: Therapeutic potential via antioxidant activity 

      Vasincu, A.; Paulsen, B. S.; Diallo, D.; Vasincu, I.; Aprotosoaie, A. C.; Bild, V.; Charalambous, Christina; Constantinou, Andreas I.; Miron, A.; Gavrilescu, C. M. (2014)
      The roots of Vernonia kotschyana Sch. Bip. ex Walp. (Asteraceae) are used in Malian traditional medicine in the treatment of gastroduodenal ulcers and gastritis. Since oxidative stress is involved in gastric ulceration, ...
    • Article  

      Lack of association between endothelial nitric oxide synthase gene polymorphisms and risk of premature coronary artery disease in the Greek population 

      Vasilakou, M.; Votteas, V.; Kasparian, C.; Pantazopoulos, N.; Dedoussis, George V. Z.; Constantinou-Deltas, Constantinos D.; Nastos, P.; Nikolakis, D.; Lamnissou, Klea (2008)
      Objective - Genetic polymorphisms in the gene for endothelial nitric oxide synthase have been considered as potential risk factors for the development of coronary artery disease in some populations. Methods - We studied ...
    • Article  

      Genotype-phenotype correlation in X-linked Alport syndrome patients carrying missense mutations in the collagenous domain of COL4A5 

      Tsiakkis, D.; Pieri, Myrtani; Koupepidou, P.; Demosthenous, Panayiota; Panayidou, K.; Constantinou-Deltas, Constantinos D. (2012)
    • Article  

      Biodiversity patterns of terrestrial isopods from two island groups in the Aegean Sea (Greece): Species-area relationship, small island effect, and nestedness 

      Triantis, Kostas A.; Sfenthourakis, Spyros; Mylonas, Moisis (2008)
      Although almost one third of Aegean islands have an area smaller than 1 km2, very few studies have concentrated on this spatial Scale. We investigate biodiversity patterns of terrestrial isopods in 2 island groups (Kalymnos ...
    • Article  

      Persistent HIV-1 infection of natural killer cells in patients receiving highly active antiretroviral therapy 

      Valentin, A.; Rosati, M.; Patenaude, D. J.; Hatzakis, Angelos E.; Kostrikis, Leontios G.; Lazanas, Marios C.; Wyvill, K. M.; Yarchoan, R.; Pavlakis, G. N. (2002)
      We have identified a subset of CD56+CD3- human natural killer (NK) cells that express CD4 and the HIV coreceptors CCR5 and CXCR4. These cells can be productively infected in vitro by both CCR5- and CXCR4-using molecular ...
    • Article  

      CXCR4 mediates entry and productive infection of syncytia-inducing (x4) hiv-1 strains in primary macrophages 

      Valentin, A.; Trivedi, H.; Lu, W.; Kostrikis, Leontios G.; Pavlakis, G. N. (2000)
      CCR5 and CXCR4 are the main coreceptors for non-syncytia-inducing (NSI) and syncytia-inducing (SI) HIV-1 strains, respectively. NSI HIV-1 isolates do not infect either human lymphoid or monocytoid cell lines, and this ...
    • Article  

      Drosophila melanogaster: A first step and a stepping-stone to anti-infectives 

      Tzelepis, Ilias; Kapsetaki, Stefania Elisavet; Panayidou, S.; Apidianakis, Yiorgos (2013)
      Following an expansion in the antibiotic drug discovery in the previous century, we now face a bottleneck in the production of new anti-infective drugs. Traditionally, chemical libraries are screened either using in vitro ...
    • Article  

      Substitutions for glycine α1-637 and glycine α2-694 of type I procollagen in lethal osteogenesis imperfecta: The conformational strain on the triple helix introduced by a glycine substitution can be transmitted along the helix 

      Tsuneyoshi, T.; Westerhausen, A.; Constantinou-Deltas, Constantinos D.; Prockop, D. J. (1991)
      Two substitutions for glycine in the triple-helical domain were found in type I procollagen synthesized by skin fibroblasts from two probands with lethal osteogenesis imperfecta. One was a substitution of valine for glycine ...
    • Article  

      Automated species recognition of antbirds in a Mexican rainforest using hidden Markov models 

      Trifa, V. M.; Kirschel, A. N. G.; Taylor, C. E.; Vallejo, E. E. (2008)
      Behavioral and ecological studies would benefit from the ability to automatically identify species from acoustic recordings. The work presented in this article explores the ability of hidden Markov models to distinguish ...
    • Article  

      The effect of the phytoestrogens genistein, daidzein, and equol on the growth of tamoxifen-resistant T47D/PKCα 

      Tonetti, D. A.; Zhang, Y.; Zhao, H.; Lim, S. -B; Constantinou, Andreas I. (2007)
      Soy supplements are often consumed by women for alleviating menopausal symptoms or for the perceived protective effects against breast cancer. More concerning is the concurrent consumption of soy isoflavones with tamoxifen ...
    • Article  

      Synchronous parallel composition in a process calculus for ecological models 

      Toro, Mauricio; Philippou, Anna; Kassara, Christina; Sfenthourakis, Spyros (2014)
      In this paper we extend PALPS, a process calculus proposed for the spatially-explicit, individual-based modeling of ecological systems, with a synchronous parallel operator. The semantics of the resulting calculus, S-PALPS, ...
    • Article  

      Stable transfection of an estrogen receptor beta cDNA isoform into MDA-MB-231 breast cancer cells 

      Tonetti, D. A.; Rubenstein, R.; DeLeon, M.; Zhao, H.; Pappas, S. G.; Bentrem, D. J.; Chen, B.; Constantinou, Andreas I.; Jordan, V. C. (2003)
      We previously reported stable transfection of estrogen receptor alpha (ERα) into the ER-negative MDA-MB-231 cells (S30) as a tool to examine the mechanism of action of estrogen and antiestrogens [J. Natl. Cancer Inst. 84 ...
    • Article  

      Changes in T Cell Receptor Excision DNA Circle (TREC) Levels in HIV Type 1-Infected Subjects Pre- and Post-Highly Active Antiretroviral Therapy 

      Touloumi, G.; Pantazis, N.; Karafoulidou, A.; Mandalaki, T.; Goedert, J. J.; Kostrikis, Leontios G.; Hatzakis, Angelos E. (2004)
      The T cell receptor excision DNA circle (TREC) level is an independent predictor of HIV-1 disease prognosis. We studied the temporal changes in TREC levels prior to and after highly active antiretroviral therapy (HAART) ...
    • Article  

      Island biogeography is not a single-variable discipline: The small island effect debate 

      Triantis, Kostas A.; Sfenthourakis, Spyros (2012)
      In some island systems, an 'anomalous' feature of species richness on smaller islands, in comparison with larger ones, has been observed. This has been described as the small island effect (SIE). The precise meaning of the ...
    • Article  

      Treatment-associated polymorphisms in protease are significantly associated with higher viral load and lower CD4 count in newly diagnosed drug-naive HIV-1 infected patients 

      Moutschen, M.; Theys, K.; Deforche, K.; Vercauteren, J.; Libin, P.; van de Vijver, D. A. M. C.; Albert, Jan; Åsjö, Birgitta; Balotta, Claudia; Bruckova, M.; Camacho, Ricardo J.; Clotet, B.; Coughlan, S.; Grossman, Z.; Hamouda, O.; Horban, A.; Korn, K.; Kostrikis, Leontios G.; Kücherer, C.; Nielsen, C.; Paraskevis, Dimitrios N.; Poljak, M.; Puchhammer-Stockl, E.; Riva, C.; Ruiz, L.; Liitsola, K.; Schmit, J. -C; Schuurman, R.; Sönnerborg, A.; Stanekova, D.; Stanojevic, M.; Struck, D.; Van Laethem, K.; Wensing, A. M. J.; Boucher, C. A. B.; Vandamme, A. M.; Puchhammer-Stockl, E.; Sarcletti, M.; Schmied, B.; Geit, M.; Balluch, G.; Vandamme, A. M.; Vercauteren, J.; Derdelinckx, I.; Sasse, A.; Bogaert, M.; Ceunen, H.; De Roo, A.; De Wit, S.; Deforche, K.; Echahidi, F.; Fransen, K.; Goffard, J. -C; Goubau, P.; Goudeseune, E.; Yombi, J. -C; Lacor, P.; Liesnard, C.; Pierard, D.; Rens, R.; Schrooten, Y.; Vaira, D.; Van den Heuvel, A.; Van Der Gucht, B.; Van Ranst, M.; Van Wijngaerden, E.; Vandercam, B.; Vekemans, M.; Verhofstede, C.; Clumeck, N.; Van Laethem, K.; Demetriades, Ioannis; Kousiappa, Ioanna; Demetriou, Victoria L.; Hezka, Johana; Linka, M.; Bruckova, M.; Machala, L.; Nielsen, C.; Jrgensen, L. B.; Gerstoft, J.; Mathiesen, L.; Pedersen, C.; Nielsen, H.; Laursen, A.; Kvinesdal, B.; Liitsola, K.; Ristola, M.; Suni, J.; Sutinen, J.; Korn, K.; K̈ucherer, C.; Berg, T.; Braun, P.; Poggensee, G.; Däumer, M.; Eberle, J.; Heiken, H.; Kaiser, R.; Knechten, H.; Müller, H.; Neifer, S.; Schmidt, B.; Walter, H.; Gunsenheimer-Bartmeyer, B.; Harrer, T.; Hatzakis, Angelos E.; Paraskevis, Dimitrios N.; Magiorkinis, Emmanouil N.; Hatzitheodorou, Eleni; Issaris, C.; Haida, Catherine; Zavitsanou, Assimina; Magiorkinis, Gkikas; Lazanas, Marios C.; Chini, Maria C.; Magafas, N.; Tsogas, Nickolaos; Paparizos, Vassilios A.; Kourkounti, Sofia; Antoniadou, Anastasia C.; Papadopoulos, Antonios I.; Panagopoulos, Periklis; Poulakou, Garyphallia G.; Sakka, V.; Chryssos, Georgios; Drimis, Stylianos; Gargalianos, Panagiotis; Lelekis, Moyssis I.; Xilomenos, G.; Psichogiou, Mina A.; Daikos, George L.; Panos, George; Haratsis, G.; Kordossis, Theodore; Kontos, Athanasios N.; Koratzanis, Georgios; Theodoridou, Maria C.; Mostrou, Glykeria J.; Spoulou, Vana I.; Hall, W.; De Gascun, C.; Byrne, C.; Duffy, M.; Bergin, C.; Reidy, D.; Farrell, G.; Lambert, J.; O'Connor, E.; Rochford, A.; Low, J.; Coakely, P.; Coughlan, S.; Grossman, Z.; Levi, I.; Chemtob, D.; Balotta, Claudia; Riva, C.; Mussini, C.; Caramma, I.; Capetti, A.; Colombo, M. C.; Rossi, C.; Prati, F.; Tramuto, F.; Vitale, F.; Ciccozzi, M.; Angarano, G.; Rezza, G.; Schmit, J. C.; Struck, D.; Hemmer, R.; Arendt, V.; Staub, T.; Schneider, F.; Roman, F.; Wensing, A. M. J.; Boucher, C. A. B.; van Bentum, P. H. M.; Brinkman, K.; op de Coul, E. L.; van der Ende, M. E.; Hoepelman, I. M.; van Kasteren, M.; Juttmann, J.; Kuipers, M.; Langebeek, N.; Richter, C.; Santegoets, R. M. W. J.; Schrijnders-Gudde, L.; Schuurman, R.; van de Ven, B. J. M.; Åsjö, Birgitta; Ormaasen, V.; Aavitsland, P.; Horban, A.; Stanczak, J. J.; Stanczak, G. P.; Firlag-Burkacka, E.; Wiercinska-Drapalo, A.; Jablonowska, E.; Malolepsza, E.; Leszczyszyn-Pynka, M.; Szata, W.; Camacho, Ricardo J.; Palma, C.; Borges, F.; Paix̃ao, T.; Duque, V.; Araújo, F.; Jevtovic, D. J.; Salemovic, D.; Stanekova, D.; Habekova, M.; Mokráš, Miloš; Truska, P.; Poljak, M.; Babic, Dunja Z.; Tomazic, J.; Vidmar, L.; Karner, P.; Clotet, B.; Gutíerrez, C.; deMendoza, C.; Erkicia, I.; Domingo, P.; Camino, X.; Galindo, M. J.; Blanco, J. L.; Leal, M.; Masabeu, A.; Guelar, A.; Llibre, J. M.; Margall, N.; Iribarren, J. A.; Gutierrez, S.; Baldov́i, J. F.; Pedreira, J. D.; Gatell, J. M.; Moreno, S.; de Mendoza, C.; Soriano, V.; Ruiz, L.; Albert, Jan; Blaxhult, A.; Heidarian, A.; Karlsson, A.; Aperia-Peipke, K.; Bergbrant, I. -M; Gissĺen, M.; Svennerholm, M.; Björkman, Per; Bratt, G.; Carlsson, M.; Ekvall, H.; Ericsson, M.; Ḧofer, M.; Johansson, B.; Sonnerb̈org, A.; Kuylenstierna, N.; Ljungberg, B.; Mäkitalo, S.; Strand, A.; Öberg, S. (2012)
      Background: The effect of drug resistance transmission on disease progression in the newly infected patient is not well understood. Major drug resistance mutations severely impair viral fitness in a drug free environment, ...
    • Article  

      Evidence for high-risk haplotypes and (CGG)n expansion in fragile X syndrome in the hellenic population of Greece and Cyprus 

      Syrrou, Maria; Patsalis, Philippos C.; Georgiou, Ioannis A.; Hadjimarcou, Michael I.; Constantinou-Deltas, Constantinos D.; Pagoulatos, G. (1996)
      The expansion of the trinucleotide repeat (CGG)n in successive generations through maternal meiosis is the cause of fragile X syndrome. Analysis of CA repeat polymorphisms flanking the FMR-1 gene provides evidence of a ...
    • Article  

      Imaging morphogenesis, in Xenopus with Quantum Dot nanocrystals 

      Stylianou, Panayiota; Skourides, Paris A. (2009)
      Mesoderm migration is a well studied morphogenetic movement that takes place during Xenopus gastrulation. The study of mesoderm migration and other morphogenetic movements has been primarily based on in vitro assays due ...