dc.contributor.author | Barocas, V. Η | el |
dc.contributor.author | Oyen, M. L. | en |
dc.contributor.author | Stylianopoulos, T. | en |
dc.contributor.author | Calvin, S. E. | en |
dc.contributor.author | Cook, R. F. | en |
dc.contributor.editor | C, Viney | en |
dc.contributor.editor | K, Katti | en |
dc.contributor.editor | F.J, Ulm | en |
dc.contributor.editor | C, Hellmich | en |
dc.creator | Barocas, V. Η | el |
dc.creator | Oyen, M. L. | en |
dc.creator | Stylianopoulos, T. | en |
dc.creator | Calvin, S. E. | en |
dc.creator | Cook, R. F. | en |
dc.date.accessioned | 2019-05-06T12:24:15Z | |
dc.date.available | 2019-05-06T12:24:15Z | |
dc.date.issued | 2005 | |
dc.identifier.uri | http://gnosis.library.ucy.ac.cy/handle/7/48678 | |
dc.description.abstract | Chorioamnion, the membrane surrounding a fetus during gestation (the "amniotic sac"), is a structural soft tissue for which the mechanical behavior is poorly understood-despite its critical role in maintaining a successful pregnancy and delivery. Preterm rupture of the chorioamnion accounts for one third of all premature births. The structural component of chorioamnion is the amnion sublayer, which provides the membrane's mechanical integrity via a dense collagen network. Amnion uniaxial and planar equi-biaxial tension testing was performed using monotonie loading, cyclic loading and stress-relaxation. The prefailure material behavior was highly nonlinear, exhibiting an approximately quadratic response. Cyclic testing, both uniaxial and biaxial, exhibited dramatic energy dissipation in the first cycle followed by less hysteresis on subsequent cycles and an eventual stable hysteresis response with approximately 20% energy dissipation per cycle. Stress-relaxation testing, both uniaxial and biaxial, demonstrated a load dependent response and continued relaxation after long hold times. A nonlinear viscoelastic (separable) hereditary integral approach was used to model the amnion stress-strain-time response during relaxation. The mechanical results are discussed within the context of the in vivo clinical performance of amnion, and the potential for membrane repair. © 2005 Materials Research Society. | en |
dc.language.iso | eng | en |
dc.publisher | Affiliation: Department of Biophysical Sciences and Medical Physics, University of Minnesota, Minneapolis, MN 55455, United States | en |
dc.publisher | Affiliation: Department of Chemical Engineering and Materials Science, University of Minnesota, Minneapolis, MN 55455, United States | en |
dc.publisher | Affiliation: Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN 55455, United States | en |
dc.publisher | Affiliation: Department of Obstetrics, Gynecology and Women's Health, University of Minnesota, Minneapolis, MN 55455, United States | en |
dc.publisher | Affiliation: Minnesota Perinatal Physicians/Allina Health System, Minneapolis, MN 55407, United States | en |
dc.publisher | Correspondence Address: Oyen, M.L. | en |
dc.publisher | Department of Biophysical Sciences and Medical Physics, University of Minnesota, Minneapolis, MN 55455, United States | en |
dc.source | Materials Research Society Symposium Proceedings | en |
dc.subject | Gestation | en |
dc.subject | Collagen | en |
dc.subject | Energy dissipation | en |
dc.subject | Viscoplasticity | en |
dc.subject | Tissue | en |
dc.subject | Stress relaxation | en |
dc.subject | Scanning electron microscopy | en |
dc.subject | Biological membranes | en |
dc.subject | Cyclic loads | en |
dc.subject | Clinical deformation | en |
dc.subject | Human amnion | en |
dc.subject | Hydration | en |
dc.subject | Monotonic loading | en |
dc.title | Uniaxial and biaxial mechanical behavior of human amnion | en |
dc.type | info:eu-repo/semantics/conferenceObject | |
dc.description.volume | 844 | |
dc.description.startingpage | 161 | |
dc.description.endingpage | 166 | |
dc.author.faculty | Πολυτεχνική Σχολή / Faculty of Engineering | |
dc.author.department | Τμήμα Μηχανικών Μηχανολογίας και Κατασκευαστικής / Department of Mechanical and Manufacturing Engineering | |
dc.type.uhtype | Conference Object | en |
dc.contributor.orcid | Stylianopoulos, T. [0000-0002-3093-1696] | |
dc.description.totalnumpages | 161-166 | |
dc.gnosis.orcid | 0000-0002-3093-1696 | |