dc.contributor.author | Griffin, Maura B. | en |
dc.contributor.author | Kyriacou, Efthyvoulos C. | en |
dc.contributor.author | Pattichis, Constantinos S. | en |
dc.contributor.author | Bond, Dawn | en |
dc.contributor.author | Kakkos, Stavros K. | en |
dc.contributor.author | Sabetai, Michael | en |
dc.contributor.author | Geroulakos, George | en |
dc.contributor.author | Georgiou, Niki | en |
dc.contributor.author | Doré, C. J. | en |
dc.contributor.author | Nicolaïdes, Andrew N. | en |
dc.creator | Griffin, Maura B. | en |
dc.creator | Kyriacou, Efthyvoulos C. | en |
dc.creator | Pattichis, Constantinos S. | en |
dc.creator | Bond, Dawn | en |
dc.creator | Kakkos, Stavros K. | en |
dc.creator | Sabetai, Michael | en |
dc.creator | Geroulakos, George | en |
dc.creator | Georgiou, Niki | en |
dc.creator | Doré, C. J. | en |
dc.creator | Nicolaïdes, Andrew N. | en |
dc.date.accessioned | 2019-11-13T10:40:18Z | |
dc.date.available | 2019-11-13T10:40:18Z | |
dc.date.issued | 2010 | |
dc.identifier.uri | http://gnosis.library.ucy.ac.cy/handle/7/54051 | |
dc.description.abstract | Objectives: The aim was to determine the diagnostic value of a juxtaluminal black (hypoechoic) area without a visible echogenic cap (JBA) in ultrasonic images of internal carotid artery plaques. Methods: Ultrasonic images of plaques from 324 patients with asymptomatic (n = 139) and symptomatic (n = 185) internal carotid 50% to 99% stenosis in relation to the bulb (European Carotid Surgery Trial) referred for duplex scanning were studied. The JBA in mm2 and the gray-scale median (GSM) were obtained after image normalization. Cut-off points for GSM and JBA (combined highest sensitivity with highest specificity) were determined from receiver operator characteristic (ROC) curves. Results: JBA ≥ 8 mm2 was associated with a high prevalence of symptomatic plaques in all grades of stenosis. In a multiple logistic regression model, increasing stenosis (mild, moderate, severe), GSM ≤ 15 and JBA ≥ 8 mm2 were independent predictors of the presence of hemispheric symptoms. This model could identify a high-risk group of 188 plaques that contained 142 (77%) of the 185 symptomatic plaques (odds ratio [OR], 6.7 | en |
dc.description.abstract | 95% confidence interval [CI], 4.08-10.91), (P < .001), (sensitivity: 77% | en |
dc.description.abstract | specificity 66% | en |
dc.description.abstract | positive predictive value 75% | en |
dc.description.abstract | negative predictive value 68%). Conclusions: The results of this study indicate the diagnostic value and for the first time suggest a cut-off point of 8 mm2 for JBA. This cut-off point needs to be validated in other groups and then applied to prospective studies of asymptomatic patients. © 2010 Society for Vascular Surgery. | en |
dc.source | Journal of Vascular Surgery | en |
dc.source.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-77953688134&doi=10.1016%2fj.jvs.2010.02.265&partnerID=40&md5=5fca673b799773e2a4530de18b407a24 | |
dc.subject | article | en |
dc.subject | human | en |
dc.subject | Humans | en |
dc.subject | Cross-Sectional Studies | en |
dc.subject | major clinical study | en |
dc.subject | Predictive Value of Tests | en |
dc.subject | priority journal | en |
dc.subject | prospective study | en |
dc.subject | Odds Ratio | en |
dc.subject | multivariate logistic regression analysis | en |
dc.subject | Logistic Models | en |
dc.subject | Risk Assessment | en |
dc.subject | high risk population | en |
dc.subject | ultrasound | en |
dc.subject | diagnostic value | en |
dc.subject | Pilot Projects | en |
dc.subject | sensitivity and specificity | en |
dc.subject | Severity of Illness Index | en |
dc.subject | predictive validity | en |
dc.subject | receiver operating characteristic | en |
dc.subject | carotid artery obstruction | en |
dc.subject | Carotid Artery, Internal | en |
dc.subject | carotid atherosclerosis | en |
dc.subject | Carotid Stenosis | en |
dc.subject | Cerebrovascular Disorders | en |
dc.subject | Doppler echography | en |
dc.subject | Gray scale echography | en |
dc.subject | internal carotid artery | en |
dc.subject | juxtaluminal hypoechoic area | en |
dc.subject | ROC Curve | en |
dc.subject | Ultrasonography, Doppler, Duplex | en |
dc.title | Juxtaluminal hypoechoic area in ultrasonic images of carotid plaques and hemispheric symptoms | en |
dc.type | info:eu-repo/semantics/article | |
dc.identifier.doi | 10.1016/j.jvs.2010.02.265 | |
dc.description.volume | 52 | |
dc.description.issue | 1 | |
dc.description.startingpage | 69 | |
dc.description.endingpage | 76 | |
dc.author.faculty | 002 Σχολή Θετικών και Εφαρμοσμένων Επιστημών / Faculty of Pure and Applied Sciences | |
dc.author.department | Τμήμα Πληροφορικής / Department of Computer Science | |
dc.type.uhtype | Article | en |
dc.description.notes | <p>Cited By :32</p> | en |
dc.source.abbreviation | J.Vasc.Surg. | en |
dc.contributor.orcid | Pattichis, Constantinos S. [0000-0003-1271-8151] | |
dc.contributor.orcid | Kyriacou, Efthyvoulos C. [0000-0002-4589-519X] | |
dc.gnosis.orcid | 0000-0003-1271-8151 | |
dc.gnosis.orcid | 0000-0002-4589-519X | |