Impact of head rotation on the individualized common carotid flow and carotid bifurcation hemodynamics
Georgiou, Georgios C.
Brott, B. C.
Nicolaïdes, Andrew N.
Anayiotos, Andreas S.
SourceIEEE Journal of Biomedical and Health Informatics
Google Scholar check
MetadataShow full item record
This paper aims at evaluating the changes that head rotation poses on morphological and flow characteristics of the carotid bifurcation (CB) and on the distribution of parameters that are regarded as important in atherosclerosis development, such as relative particle residence time (RRT), normalized oscillatory shear index (nOSI), and helicity (HL). Using a subject-specific approach, six healthy volunteers were MR-scanned in two head postures: supine neutral and prone with rightward head rotation. Cross-sectional flow velocity distribution was obtained using phase-contrast MRI at the common carotid artery (CCA). Our results indicate that peak systolic flow rate is reduced at the prone position in most cases for both CCAs. Morphological MR images are used to segment and construct the CB models. Numerical simulations are performed and areas exposed to high helicity or unfavorable hemodynamics are calculated. Head rotation affects the instantaneous spatial extent of high helicity regions. Posture-related observed differences in the distribution of nOSI and RRT suggest that inlet flow waveform tends to moderate geometry-induced changes in the qualitative and quantitative distribution of atherosclerosis-susceptible wall regions. Overall, presented results indicate that an individualized approach is required to fully assess the postural role in atherosclerosis development and in complications arising in stenotic and stented vessels. © 2013 IEEE.
Showing items related by title, author, creator and subject.
Manual and automated intima-media thickness and diameter measurements of the common carotid artery in patients with renal failure disease Loizou, Christos P.; Kasparis, Takis; Lazarou, Theodoros; Pattichis, Constantinos S.; Pantzaris, Marios C. (2014)The objective of this study was to investigate differences in intima-media thickness (IMT) and diameter (D) measurements of the common carotid artery (CCA) in ultrasound imaging in normal subjects and renal failure disease ...
Snakes based segmentation of the common carotid artery intima media Loizou, Christos P.; Pattichis, Constantinos S.; Pantzaris, Marios C.; Tyllis, Theodosis K.; Nicolaïdes, Andrew N. (2007)Ultrasound measurements of the human carotid artery walls are conventionally obtained by manually tracing interfaces between tissue layers. In this study we present a snakes segmentation technique for detecting the ...
Ultrasound image texture analysis of the intima and media layers of the common carotid artery and its correlation with age and gender Loizou, Christos P.; Pantzaris, Marios C.; Pattichis, Marios S.; Kyriacou, Efthyvoulos C.; Pattichis, Constantinos S. (2009)The intima-media thickness (IMT) of the common carotid artery (CCA) is widely used as an early indicator of cardiovascular disease (CVD). It was proposed but not thoroughly investigated that the composition and texture of ...