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Development of a de novo Molecular Beacon-Based Real-Time RT-PCR Assay for the Detection and Discrimination of SARS-CoV-2 Variants of Concern
(Πανεπιστήμιο Κύπρου, Σχολή Θετικών και Εφαρμοσμένων Επιστημών / University of Cyprus, Faculty of Pure and Applied Sciences, 2022-12-16)
The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) emerged in late 2019 and is the causative agent of the Coronavirus Disease 2019 (COVID-19). Since its emergence it has led to a global pandemic with devastating ...
Molecular pathways affected by HBx protein and their targeting for therapy of Hepatocellular carcinoma
(Πανεπιστήμιο Κύπρου, Σχολή Θετικών και Εφαρμοσμένων Επιστημών / University of Cyprus, Faculty of Pure and Applied Sciences, 2022-12-09)
Hepatitis B virus (HBV) infection can cause several types of liver disease including acute hepatitis, chronic hepatitis, and liver cirrhosis. It is also considered a significant risk factor for Hepatocellular carcinoma ...
Human immune responses upon SARS-CoV-2 infection- inflammation and cytokine storm
(Πανεπιστήμιο Κύπρου, Σχολή Θετικών και Εφαρμοσμένων Επιστημών / University of Cyprus, Faculty of Pure and Applied Sciences, 2022-12)
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a highly transmissible and pathogenic coronavirus that emerged in December 2019 in the city of Wuhan, China, causing the COVID-19 pandemic of acute respiratory ...
Mechanical Cell Membrane stimulation using Magnetic Tweezers increases cell membrane stiffness through integrin dependent and independent mechanisms
(Πανεπιστήμιο Κύπρου, Σχολή Θετικών και Εφαρμοσμένων Επιστημών / University of Cyprus, Faculty of Pure and Applied Sciences, 2022-12)
Several cellular processes, such as proliferation, migration tissue morphogenesis and tissue regeneration, are closely regulated by the cells ability to sense their microenvironment and translate mechanical stimuli to ...
The nexus between circRNA and prostate cancer from the complex interventions to treatment expectation
(Πανεπιστήμιο Κύπρου, Σχολή Θετικών και Εφαρμοσμένων Επιστημών / University of Cyprus, Faculty of Pure and Applied Sciences, 2022-05-20)
Circular RNAs (circRNAs) are a kind of RNA that results through a non-regular process known as alternative splicing. Because of their possible regulatory activities during gene expression, circRNAs have lately sparked ...
Spatiotemporal vocal interactions in a ground-dwelling Neotropical passerine
(Πανεπιστήμιο Κύπρου, Σχολή Θετικών και Εφαρμοσμένων Επιστημών / University of Cyprus, Faculty of Pure and Applied Sciences, 2022-05-11)
In many species, communication involves an exchange of information between the sender and the receiver, by using different types of signals. Among the different types of communication, acoustic communication has been studied ...
Recombinant Poliovirus a therapeutic agent for Cancer
(Πανεπιστήμιο Κύπρου, Σχολή Θετικών και Εφαρμοσμένων Επιστημών / University of Cyprus, Faculty of Pure and Applied Sciences, 2022-05)
Cancer is a leading cause of global mortality, and its burden is growing despite the availability of standard treatment methods. Genetically and Morphologically tumor cells differ from normal cells. However, cancers arise ...
Application of conservation genetics in conservation planning, with a special focus on the impacts of hybridization on birds and their conservation
(Πανεπιστήμιο Κύπρου, Σχολή Θετικών και Εφαρμοσμένων Επιστημών / University of Cyprus, Faculty of Pure and Applied Sciences, 2022-06-01)
Biodiversity consists of all different live forms found in Earth. It is important to sustain it as it has several important aspects, such as maintaining ecosystems, helping with their proper functioning and it also plays ...
Genetic Characterization of a Novel HIV-1 Circulating Recombinant Form (CRF91_cpx) and Identification of Three Additional Putative CRFs: Increased Prevalence of URFs and CRFs in the Polyphyletic HIV-1 Infection in Cyprus.
(Πανεπιστήμιο Κύπρου, Σχολή Θετικών και Εφαρμοσμένων Επιστημών / University of Cyprus, Faculty of Pure and Applied Sciences, 2022-05-27)
HIV is characterized by a high degree of genetic variation, as it is evident from numerous genetically distinct subtypes (within the major group M) and circulating recombinant forms (CRFs). The genetic diversity of HIV is ...
Adherens Junctions spatially guide ECM deposition by stimulating integrin activation and clustering
(Πανεπιστήμιο Κύπρου, Σχολή Θετικών και Εφαρμοσμένων Επιστημών / University of Cyprus, Faculty of Pure and Applied Sciences, 2022-05-20)
The extracellular matrix (ECM) plays an essential role in all multicellular organisms as a substrate for cell anchorage and tissue scaffolding. It is involved in diverse processes such as cell proliferation and survival, ...