Complete coding sequence, exon/intron arrangement and chromosome location of ZNF45, a KRAB-domain-containing gene
dc.contributor.author | Constantinou-Deltas, Constantinos D. | en |
dc.contributor.author | Bashiardes, Evy | en |
dc.contributor.author | Patsalis, Philippos C. | en |
dc.contributor.author | Hadjimarcou, Michael I. | en |
dc.contributor.author | Kroisel, P. M. | en |
dc.contributor.author | Ioannou, Petros A. 1953- | en |
dc.contributor.author | Roses, A. D. | en |
dc.contributor.author | Lee, J. E. | en |
dc.creator | Constantinou-Deltas, Constantinos D. | en |
dc.creator | Bashiardes, Evy | en |
dc.creator | Patsalis, Philippos C. | en |
dc.creator | Hadjimarcou, Michael I. | en |
dc.creator | Kroisel, P. M. | en |
dc.creator | Ioannou, Petros A. 1953- | en |
dc.creator | Roses, A. D. | en |
dc.creator | Lee, J. E. | en |
dc.date.accessioned | 2019-11-04T12:50:25Z | |
dc.date.available | 2019-11-04T12:50:25Z | |
dc.date.issued | 1996 | |
dc.identifier.uri | http://gnosis.library.ucy.ac.cy/handle/7/53017 | |
dc.description.abstract | Zinc finger genes represent a large multigene family present in mammalian and other genomes. A subgroup of these genes contain a conserved motif, the KRAB domain, at the NH2-terminal region, which was recently shown to posses a potent transcriptional repression activity. For one such gene, ZNF45, we determined the complete coding sequence, along with the exon/intron arrangement and the splice junctions. Exon 2 codes exclusively for the KRAB-A element of 42 amino acids, and exon 4 contains the 19 zinc finger repeats. In addition, we generated an EST (expressed sequence tag) from the 3'-end of ZNF45 that we used for polymerase chain reaction screening of a P1-derived genomic library. We isolated a 65-kb clone that was used for localizing this gene on chromosome 19q13.2 by fluorescence in situ hybridization. | en |
dc.source | Cytogenetics and cell genetics | en |
dc.source.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-8044229065&partnerID=40&md5=5fc8e609b5e95b9e98344c0b47b60386 | |
dc.subject | article | en |
dc.subject | human | en |
dc.subject | Humans | en |
dc.subject | priority journal | en |
dc.subject | exon | en |
dc.subject | Genes | en |
dc.subject | Base Sequence | en |
dc.subject | Exons | en |
dc.subject | Molecular Sequence Data | en |
dc.subject | intron | en |
dc.subject | Introns | en |
dc.subject | polymerase chain reaction | en |
dc.subject | nucleotide sequence | en |
dc.subject | Repressor Proteins | en |
dc.subject | Amino Acid Sequence | en |
dc.subject | zinc finger protein | en |
dc.subject | Chromosome Mapping | en |
dc.subject | In Situ Hybridization, Fluorescence | en |
dc.subject | chromosomal localization | en |
dc.subject | chromosome 19q | en |
dc.subject | Chromosomes, Human, Pair 19 | en |
dc.subject | Consensus Sequence | en |
dc.subject | gene library | en |
dc.subject | gene structure | en |
dc.subject | molecular cloning | en |
dc.subject | Multigene Family | en |
dc.subject | Protein Structure, Tertiary | en |
dc.subject | rna splicing | en |
dc.subject | Sequence Alignment | en |
dc.subject | sequence tagged site | en |
dc.title | Complete coding sequence, exon/intron arrangement and chromosome location of ZNF45, a KRAB-domain-containing gene | en |
dc.type | info:eu-repo/semantics/article | |
dc.description.volume | 75 | |
dc.description.startingpage | 230 | |
dc.description.endingpage | 233 | |
dc.author.faculty | Σχολή Θετικών και Εφαρμοσμένων Επιστημών / Faculty of Pure and Applied Sciences | |
dc.author.department | Τμήμα Βιολογικών Επιστημών / Department of Biological Sciences | |
dc.type.uhtype | Article | en |
dc.description.notes | <p>Cited By :9</p> | en |
dc.source.abbreviation | Cytogenet.Cell Genet. | en |
dc.contributor.orcid | Constantinou-Deltas, Constantinos D. [0000-0001-5549-9169] | |
dc.gnosis.orcid | 0000-0001-5549-9169 |
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