dc.contributor.author | Paraskevis, Dimitrios N. | en |
dc.contributor.author | Magiorkinis, M. | en |
dc.contributor.author | Vandamme, A. M. | en |
dc.contributor.author | Kostrikis, Leontios G. | en |
dc.contributor.author | Hatzakis, Angelos E. | en |
dc.creator | Paraskevis, Dimitrios N. | en |
dc.creator | Magiorkinis, M. | en |
dc.creator | Vandamme, A. M. | en |
dc.creator | Kostrikis, Leontios G. | en |
dc.creator | Hatzakis, Angelos E. | en |
dc.date.accessioned | 2019-11-04T12:52:27Z | |
dc.date.available | 2019-11-04T12:52:27Z | |
dc.date.issued | 2001 | |
dc.identifier.uri | http://gnosis.library.ucy.ac.cy/handle/7/53291 | |
dc.description.abstract | Human immunodeficiency virus type 1 (HIV-1) has been classified into three main groups and 11 distinct subtypes. Moreover, several circulating recombinant forms (CRFs) of HIV-1 have been recently documented to have spread widely causing extensive HIV-1 epidemics. A subtype, initially designated I (CRFO4∐x), was documented in Cyprus and Greece and was found to comprise regions of sequence derived from subtypes A and G as well as regions of unclassified sequence. Reanalysis of the three full-length CRFO4∐x sequences that were available revealed a mosaic genomic organization of unique complexity comprising regions of sequence from at least five distinct subtypes, A, G, H, K and unclassified regions. These strains account for approximately 2% of the total HIV-1-infected population in Greece, thus providing evidence of the great capability of HIV-1 to recombine and produce highly divergent strains which can be spread successfully through different infection routes. | en |
dc.source | Journal of General Virology | en |
dc.source.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0035109544&partnerID=40&md5=b64b97df7d8cf05f4140a0e6e2066042 | |
dc.subject | Cyprus | en |
dc.subject | Greece | en |
dc.subject | article | en |
dc.subject | human | en |
dc.subject | Humans | en |
dc.subject | controlled study | en |
dc.subject | priority journal | en |
dc.subject | Human immunodeficiency virus infection | en |
dc.subject | epidemic | en |
dc.subject | Human immunodeficiency virus | en |
dc.subject | virus strain | en |
dc.subject | population research | en |
dc.subject | nonhuman | en |
dc.subject | gene sequence | en |
dc.subject | Viral Proteins | en |
dc.subject | genetic analysis | en |
dc.subject | Human immunodeficiency virus 1 | en |
dc.subject | HIV-1 | en |
dc.subject | Phylogeny | en |
dc.subject | sequence analysis | en |
dc.subject | genetic epidemiology | en |
dc.subject | virus classification | en |
dc.subject | virus recombination | en |
dc.subject | virus virulence | en |
dc.subject | gene order | en |
dc.subject | Recombination, Genetic | en |
dc.subject | mosaicism | en |
dc.subject | virus isolation | en |
dc.subject | strain difference | en |
dc.subject | HIV Antigens | en |
dc.subject | HIV Envelope Protein gp120 | en |
dc.subject | Capsid | en |
dc.subject | viral genetics | en |
dc.subject | Capsid Proteins | en |
dc.subject | Gene Products, gag | en |
dc.subject | Gene Products, pol | en |
dc.subject | Gene Products, vif | en |
dc.subject | HIV Core Protein p24 | en |
dc.subject | HIV Envelope Protein gp41 | en |
dc.subject | RNA viruses | en |
dc.subject | virus recombinant | en |
dc.title | Re-analysis of human immunodeficiency virus type 1 isolates from Cyprus and Greece, initially designated 'subtype I', reveals a unique complex A/G/H/K/? mosaic pattern | en |
dc.type | info:eu-repo/semantics/article | |
dc.description.volume | 82 | |
dc.description.startingpage | 575 | |
dc.description.endingpage | 580 | |
dc.author.faculty | Σχολή Θετικών και Εφαρμοσμένων Επιστημών / Faculty of Pure and Applied Sciences | |
dc.author.department | Τμήμα Βιολογικών Επιστημών / Department of Biological Sciences | |
dc.type.uhtype | Article | en |
dc.description.notes | <p>Cited By :18</p> | en |
dc.source.abbreviation | J.Gen.Virol. | en |
dc.contributor.orcid | Kostrikis, Leontios G. [0000-0002-5340-7109] | |
dc.contributor.orcid | Paraskevis, Dimitrios [0000-0001-6167-7152] | |
dc.gnosis.orcid | 0000-0002-5340-7109 | |
dc.gnosis.orcid | 0000-0001-6167-7152 | |